Cruises from Balboa

13 cruise lines and 19 ships sailing from Balboa, Panama

Cruises visiting Balboa

Balboa sits at the Pacific entrance to the Panama Canal, where ocean-going ships begin their passage between continents. From the port, Panama City’s skyline rises beyond the canal’s working waters. Visit Casco Viejo for restored colonial streets, independent cafés and views across the bay. Or follow the Amador Causeway toward the Biomuseo and sweeping views of ships awaiting transit. Balboa rewards travelers who look beyond the canal to a capital shaped by trade, history and the sea.

Cruises from Balboa, Panama

Sailings departing from Balboa, earliest departure first.

38 Sailings Found
Panama City, Panama

8 Days Panama City, Panama Round Trip

National Geographic Quest

Departs
January 29th 2027
Duration
7 nights
From
$8,000
per person, double occupancy
Ports of call:
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Panama City, Panama

15 Days One-Way from Panama City to Bridgetown

Star Legend

Departs
February 16th 2027
Duration
14 nights
Request Exclusive Rates
Ports of call: +7 more ports
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Panama City, Panama

7 Days One-Way from Panama City to Oranjestad Aruba

Star Legend

Departs
February 16th 2027
Duration
6 nights
From
$5,736
per person, double occupancy
Ports of call:
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Panama City, Panama

12 Days One-Way from Panama City to Miami

Seven Seas Prestige

Departs
February 22nd 2027
Duration
11 nights
From
$28,298
per person, double occupancy
Ports of call: +4 more ports
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Panama City, Panama

23 Days Panama City, Panama Round Trip

Seven Seas Grandeur

Departs
March 9th 2027
Duration
22 nights
From
$49,298
per person, double occupancy
Ports of call: +3 more ports
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Panama City, Panama

8 Days One-Way from Panama City to San Juan

Ritz-Carlton Evrima

Departs
March 28th 2027
Duration
7 nights
From
$7,300
per person, double occupancy
Ports of call:
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Panama City, Panama

14 Days One-Way from Panama City to Miami

Seven Seas Grandeur

Departs
April 1st 2027
Duration
13 nights
From
$24,898
per person, double occupancy
Ports of call: +6 more ports
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Panama City, Panama

12 Days One-Way from Panama City to Los Angeles

MSC Explora 3

Departs
April 22nd 2027
Duration
11 nights
From
$7,280
per person, double occupancy
Ports of call: +1 more port
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Panama City, Panama

19 Days One-Way from Panama City to Vancouver

MSC Explora 3

Departs
April 22nd 2027
Duration
18 nights
From
$11,840
per person, double occupancy
Ports of call: +5 more ports
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Panama City, Panama

14 Days One-Way from Panama City to New York

Crystal Serenity

Departs
August 21st 2027
Duration
13 nights
From
$6,360
per person, double occupancy
Ports of call: +4 more ports
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Panama City, Panama

26 Days One-Way from Panama City to Buenos Aires

Scenic Eclipse

Departs
October 31st 2027
Duration
25 nights
From
$37,810
per person, double occupancy
Ports of call: +9 more ports
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Panama City, Panama

11 Days One-Way from Panama City to Fort Lauderdale

Crystal Serenity

Departs
December 12th 2027
Duration
10 nights
From
$5,070
per person, double occupancy
Ports of call: +3 more ports
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Cruise lines embarking (starting) at Balboa (13)

Cruise lineCategoryTypeShips departing from Balboa
Regent Seven Seas Cruises Ultra Luxury Ocean Seven Seas Grandeur, Seven Seas Prestige, Seven Seas Splendor
Ritz-Carlton Yacht Collection Ultra Luxury Ocean Ritz-Carlton Evrima
MSC Explora Journeys Luxury Ocean MSC Explora 3
Oceania Cruises Luxury Ocean Oceania Marina, Oceania Sonata, Oceania Vista
Scenic Cruises Luxury Ocean Scenic Eclipse
Azamara Cruises Premium Ocean Azamara Quest
Crystal Cruises Premium Ocean Crystal Serenity
Emerald Cruises Premium Ocean Emerald Azzurra
Hapag-Lloyd Cruises Premium Ocean ms Europa 2
Lindblad Expeditions Premium Expedition National Geographic Quest
Viking Cruises Premium Ocean Viking Mars
Windstar Cruises Premium Ocean Star Legend, Star Pride
Star Clippers Ocean Royal Clipper, Star Clipper

The complete Waterways Cruise destination guide to Balboa, Panama →

13
Cruise lines
19
Ships departing

Published September 2, 2026