Cruises from Prague

9 cruise lines and 30 ships sailing from Prague, Czechia - Czech Republic

Cruises visiting Prague

Prague is best explored on foot, where Gothic spires, Baroque façades and quiet lanes reveal the city’s layered past. Cross Charles Bridge early, before the crowds, then climb towards Prague Castle for sweeping views over the Vltava. In Old Town Square, the Astronomical Clock draws visitors at the hour. Leave time for a riverside café and a measured look at a city that wears its history in daily life.

Cruises from Prague, Czechia - Czech Republic

Sailings departing from Prague, earliest departure first.

91 Sailings Found
Prague, Czechia - Czech Republic

8 Days One-Way from Prague to Frankfurt Am Main

Avalon Tranquility II

Departs
December 9th 2026
Duration
7 nights
From
$4,942
per person, double occupancy
Ports of call:
Prague, Czechia - Czech Republic

12 Days One-Way from Prague to Basel

Avalon Tranquility II

Departs
December 9th 2026
Duration
11 nights
From
$9,269
per person, double occupancy
Ports of call: +6 more ports
Prague, Czechia - Czech Republic

11 Days One-Way from Prague to Budapest

AmaVerde

Departs
December 11th 2026
Duration
10 nights
From
$5,324
per person, double occupancy
Ports of call: +5 more ports

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Prague, Czechia - Czech Republic

8 Days One-Way from Prague to Frankfurt Am Main

Avalon Illumination

Departs
December 11th 2026
Duration
7 nights
From
$4,835
per person, double occupancy
Ports of call:
Prague, Czechia - Czech Republic

12 Days One-Way from Prague to Basel

Avalon Illumination

Departs
December 11th 2026
Duration
11 nights
From
$5,884
per person, double occupancy
Ports of call: +6 more ports
Prague, Czechia - Czech Republic

11 Days One-Way from Prague to Regensburg

Scenic Amber

Departs
December 11th 2026
Duration
10 nights
From
$3,942
per person, double occupancy
Ports of call: +2 more ports
Prague, Czechia - Czech Republic

11 Days One-Way from Prague to Budapest

Scenic Opal

Departs
December 12th 2026
Duration
10 nights
From
$3,942
per person, double occupancy
Ports of call: +2 more ports
Prague, Czechia - Czech Republic

21 Days One-Way from Prague to Paris City

Scenic Opal

Departs
December 19th 2026
Duration
20 nights
From
$8,111
per person, double occupancy
Ports of call: +8 more ports
Prague, Czechia - Czech Republic

18 Days One-Way from Prague to Amsterdam

Scenic Opal

Departs
December 19th 2026
Duration
17 nights
From
$6,363
per person, double occupancy
Ports of call: +7 more ports
Prague, Czechia - Czech Republic

10 Days One-Way from Prague to Budapest

SS Beatrice

Departs
March 26th 2027
Duration
9 nights
Ports of call: +1 more port
Prague, Czechia - Czech Republic

10 Days One-Way from Prague to Berlin

VIVA Ruby

Departs
March 27th 2027
Duration
9 nights
From
$2,655
per person, double occupancy
Ports of call: +7 more ports
Prague, Czechia - Czech Republic

7 Days Prague, Czech Rep Round Trip

ms Elbe Princesse

Departs
April 1st 2027
Duration
6 nights
From
$1,257
per person, double occupancy
Ports of call: