Cruises from Santos

1 cruise line and 4 ships sailing from Santos, Brazil

Cruises visiting Santos

Often the gateway to São Paulo, Santos rewards a closer look before you head inland. Brazil’s busiest port has shaped national trade for generations, especially through coffee. Its story unfolds at the grand former Bolsa do Café. Along the waterfront, a long garden-lined promenade frames broad beaches and everyday city life. The historic center offers churches and old commercial streets, while nearby São Vicente recalls Brazil’s earliest colonial years.

Cruises from Santos, Brazil

Sailings departing from Santos, earliest departure first.

35 Sailings Found
Santos, Brazil

19 Days One-Way from Santos to Naples

MSC Divina

Departs
March 14th 2027
Duration
18 nights
From
$2,158
per person, double occupancy
Ports of call: +4 more ports
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Santos, Brazil

15 Days One-Way from Santos to Tarragona

MSC Musica

Departs
April 1st 2027
Duration
14 nights
From
$1,036
per person, double occupancy
Ports of call:
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Santos, Brazil

17 Days One-Way from Santos to Genoa

MSC Musica

Departs
April 1st 2027
Duration
16 nights
From
$945
per person, double occupancy
Ports of call: +1 more port
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Santos, Brazil

16 Days One-Way from Santos to Marseille

MSC Musica

Departs
April 1st 2027
Duration
15 nights
From
$912
per person, double occupancy
Ports of call:
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Santos, Brazil

22 Days One-Way from Santos to Valencia

MSC Musica

Departs
April 1st 2027
Duration
21 nights
From
$1,447
per person, double occupancy
Ports of call: +5 more ports
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Santos, Brazil

5 Days One-Way from Santos to Maceio

MSC Musica

Departs
April 1st 2027
Duration
4 nights
From
$2,789
per person, double occupancy
Ports of call:
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Santos, Brazil

24 Days One-Way from Santos to Marseille

MSC Virtuosa

Departs
April 3rd 2027
Duration
23 nights
From
$1,889
per person, double occupancy
Ports of call: +7 more ports
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Santos, Brazil

18 Days One-Way from Santos to Barcelona

MSC Virtuosa

Departs
April 3rd 2027
Duration
17 nights
From
$1,368
per person, double occupancy
Ports of call: +2 more ports
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Santos, Brazil

21 Days One-Way from Santos to Palermo

MSC Virtuosa

Departs
April 3rd 2027
Duration
20 nights
From
$1,679
per person, double occupancy
Ports of call: +4 more ports
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Santos, Brazil

22 Days One-Way from Santos to Naples

MSC Virtuosa

Departs
April 3rd 2027
Duration
21 nights
From
$1,727
per person, double occupancy
Ports of call: +5 more ports
View Voyage & Fares Request a Quote
Santos, Brazil

5 Days One-Way from Santos to Salvador De Bahia

MSC Virtuosa

Departs
April 3rd 2027
Duration
4 nights
From
$1,879
per person, double occupancy
Ports of call:
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Cruise lines embarking (starting) at Santos (1)

Cruise lineCategoryTypeShips departing from Santos
MSC Cruises Contemporary Ocean MSC Divina, MSC Musica, MSC Seaview, MSC Virtuosa

The complete Waterways Cruise destination guide to Santos, Brazil →

1
Cruise lines
4
Ships departing

Published September 30, 2026