Cruises from Southampton

11 cruise lines and 33 ships sailing from Southampton, United Kingdom

Cruises visiting Southampton

Southampton is a working port with a rich maritime past. Walk its medieval city walls, then visit SeaCity Museum, where exhibits explore the city’s connection to the Titanic. The Mayflower began its 1620 voyage from Southampton, and the Titanic sailed from here in 1912. Beyond the waterfront, the New Forest’s heathland and Winchester’s cathedral make rewarding excursions.

Cruises from Southampton, United Kingdom

Sailings departing from Southampton, earliest departure first.

255 Sailings Found
Southampton, United Kingdom

17 Days One-Way from Southampton to Copenhagen

MSC Explora 4

Departs
May 2nd 2027
Duration
16 nights
From
$12,750
per person, double occupancy
Ports of call: +6 more ports
Southampton, United Kingdom

19 Days One-Way from Southampton to Istanbul

Queen Elizabeth

Departs
May 2nd 2027
Duration
18 nights
From
$2,449
per person, double occupancy
Ports of call: +6 more ports
Southampton, United Kingdom

27 Days One-Way from Southampton to Civitavecchia-Rome

Queen Elizabeth

Departs
May 2nd 2027
Duration
26 nights
From
$2,879
per person, double occupancy
Ports of call: +11 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Southampton, United Kingdom

34 Days One-Way from Southampton to Trieste

Queen Elizabeth

Departs
May 2nd 2027
Duration
33 nights
From
$4,299
per person, double occupancy
Ports of call: +16 more ports
Southampton, United Kingdom

41 Days One-Way from Southampton to Barcelona

Queen Elizabeth

Departs
May 2nd 2027
Duration
40 nights
From
$16,029
per person, double occupancy
Ports of call: +19 more ports
Southampton, United Kingdom

13 Days One-Way from Southampton to Barcelona

Queen Elizabeth

Departs
May 2nd 2027
Duration
12 nights
From
$1,009
per person, double occupancy
Ports of call: +3 more ports
Southampton, United Kingdom

13 Days Southampton, United Kingdom Round Trip

Oceania Insignia

Departs
May 4th 2027
Duration
12 nights
From
$4,950
per person, double occupancy
Ports of call: +4 more ports
Southampton, United Kingdom

9 Days Southampton, United Kingdom Round Trip

Celebrity Apex

Departs
May 7th 2027
Duration
8 nights
From
$2,032
per person, double occupancy
Ports of call:
Southampton, United Kingdom

8 Days Southampton, United Kingdom Round Trip

Freedom Of The Seas

Departs
May 9th 2027
Duration
7 nights
From
$961
per person, double occupancy
Ports of call:
Southampton, United Kingdom

7 Days One-Way from Southampton to Copenhagen

Norwegian Star

Departs
May 9th 2027
Duration
6 nights
From
$1,239
per person, double occupancy
Ports of call:
Southampton, United Kingdom

19 Days Southampton, United Kingdom Round Trip

Queen Anne

Departs
May 9th 2027
Duration
18 nights
From
$2,059
per person, double occupancy
Ports of call: +4 more ports
Southampton, United Kingdom

4 Days Southampton, United Kingdom Round Trip

Queen Mary 2

Departs
May 9th 2027
Duration
3 nights
From
$489
per person, double occupancy
Ports of call:

Cruise lines embarking (starting) at Southampton (11)

Cruise lineCategoryTypeShips departing from Southampton
Regent Seven Seas Cruises Ultra Luxury Ocean Seven Seas Grandeur, Seven Seas Mariner, Seven Seas Prestige, Seven Seas Splendor, Seven Seas Voyager
Seabourn Cruises Ultra Luxury Ocean Seabourn Quest
Silversea Cruises Ultra Luxury Ocean Silver Dawn, Silver Spirit
MSC Explora Journeys Luxury Ocean MSC Explora 3 (no upcoming dates — contact a Waterways Cruise consultant for additional dates on MSC Explora 3 cruises departing Southampton), MSC Explora 4
Oceania Cruises Luxury Ocean Oceania Insignia, Oceania Marina, Oceania Sirena, Oceania Sonata, Oceania Vista
Celebrity Cruises Contemporary Ocean Celebrity Apex
Cunard Contemporary Ocean Queen Anne, Queen Elizabeth, Queen Mary 2, Queen Victoria
MSC Cruises Contemporary Ocean MSC Meraviglia, MSC Preziosa, MSC Virtuosa
Norwegian Cruise Line Contemporary Ocean Norwegian Jewel, Norwegian Prima, Norwegian Star, Norwegian Sun (no upcoming dates — contact a Waterways Cruise consultant for additional dates on Norwegian Sun cruises departing Southampton)
Princess Cruises Contemporary Ocean Caribbean Princess, Majestic Princess, Regal Princess, Sky Princess
Royal Caribbean Contemporary Ocean Freedom Of The Seas, Liberty Of The Seas (no upcoming dates — contact a Waterways Cruise consultant for additional dates on Liberty Of The Seas cruises departing Southampton)

The complete Waterways Cruise destination guide to Southampton, United Kingdom →

11
Cruise lines
33
Ships departing

Published September 18, 2026