Cruises to Panama Canal

Discover Panama Canal, starting from Colón, Panama

Explore Colón, Panama

Ports, excursions and things to do in Panama Canal.

Panama Canal Cruises

Sailings that call at Panama Canal, earliest departure first.

346 Sailings Found
Colon, Panama

8 Days One-Way from Colon to Puntarenas

National Geographic Quest

Departs
December 20th 2026
Duration
7 nights
From
$6,228
per person, double occupancy
Ports of call:
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Fort Lauderdale, United States

20 Days Fort Lauderdale, USA Round Trip

ms Nieuw Amsterdam

Departs
December 20th 2026
Duration
19 nights
From
$2,259
per person, double occupancy
Ports of call: +5 more ports
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Miami, United States

40 Days One-Way from Miami to Papeete

Silver Dawn

Departs
December 21st 2026
Duration
39 nights
From
$20,600
per person, double occupancy
Ports of call: +11 more ports
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Miami, United States

19 Days One-Way from Miami to Los Angeles

Silver Dawn

Departs
December 21st 2026
Duration
18 nights
From
$7,700
per person, double occupancy
Ports of call: +2 more ports
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Fort Lauderdale, United States

18 Days One-Way from Fort Lauderdale to Los Angeles

Viking Sky

Departs
December 22nd 2026
Duration
17 nights
From
$6,499
per person, double occupancy
Ports of call: +2 more ports
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Miami, United States

23 Days Miami, USA Round Trip

MSC Poesia

Departs
December 23rd 2026
Duration
22 nights
From
$2,782
per person, double occupancy
Ports of call: +2 more ports
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Puntarenas, Costa Rica

8 Days Puntarenas, Costa Rica Round Trip

Star Clipper

Departs
December 26th 2026
Duration
7 nights
From
$2,010
per person, double occupancy
Ports of call:
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land tour, train/bus travel

8 Days One-Way from Land Tour to Panama City

National Geographic Quest

Departs
December 27th 2026
Duration
7 nights
From
$6,228
per person, double occupancy
Ports of call: +4 more ports
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West Palm Beach, United States

15 Days One-Way from West Palm Beach to Fort Lauderdale

Viking Mars

Departs
December 27th 2026
Duration
14 nights
From
$6,299
per person, double occupancy
Ports of call: +3 more ports
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Los Angeles, United States

17 Days One-Way from Los Angeles to Fort Lauderdale

Island Princess

Departs
December 28th 2026
Duration
16 nights
From
$1,399
per person, double occupancy
Ports of call: +3 more ports
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Puntarenas, Costa Rica

9 Days One-Way from Puntarenas to Colon

Star Legend

Departs
December 28th 2026
Duration
8 nights
From
$4,758
per person, double occupancy
Ports of call: +2 more ports
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Miami, United States

17 Days One-Way from Miami to Los Angeles

Seven Seas Grandeur

Departs
December 29th 2026
Duration
16 nights
From
$33,898
per person, double occupancy
Ports of call: +4 more ports
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Miami, United States

15 Days One-Way from Miami to San Diego

ms Zuiderdam

Departs
January 2nd 2027
Duration
14 nights
From
$1,689
per person, double occupancy
Ports of call: +3 more ports
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Panama City, Panama

8 Days One-Way from Panama City to Land Tour

National Geographic Quest

Departs
January 3rd 2027
Duration
7 nights
From
$6,790
per person, double occupancy
Ports of call: +1 more port
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Fort Lauderdale, United States

71 Days Fort Lauderdale, USA Round Trip

ms Zaandam

Departs
January 3rd 2027
Duration
70 nights
Request Exclusive Rates
Ports of call: +28 more ports
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Miami, United States

10 Days One-Way from Miami to Panama City

Oceania Marina

Departs
January 5th 2027
Duration
9 nights
From
$3,637
per person, double occupancy
Ports of call: +3 more ports
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Miami, United States

21 Days Miami, USA Round Trip

Oceania Marina

Departs
January 5th 2027
Duration
20 nights
From
$7,599
per person, double occupancy
Ports of call: +9 more ports
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Hamburg, Germany

91 Days Hamburg, Germany Round Trip

Queen Anne

Departs
January 5th 2027
Duration
90 nights
From
$12,709
per person, double occupancy
Ports of call: +24 more ports
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Cruise Lines Visiting Panama Canal