Cruises to Panama Canal

Discover Panama Canal, starting from Colón, Panama

Panama Canal Cruises

Sailings that call at Panama Canal, earliest departure first.

346 Sailings Found
Puntarenas, Costa Rica

8 Days One-Way from Puntarenas to Panama City

Emerald Azzurra

Departs
February 22nd 2029
Duration
7 nights
Ports of call:
Panama City, Panama

19 Days One-Way from Panama City to Bridgetown

Emerald Azzurra

Departs
March 1st 2029
Duration
18 nights
From
$19,590
per person, double occupancy
Ports of call: +6 more ports
Los Angeles, United States

17 Days One-Way from Los Angeles to Miami

Seven Seas Prestige

Departs
March 5th 2029
Duration
16 nights
From
$30,598
per person, double occupancy
Ports of call: +3 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Milwaukee WI, United States

62 Days One-Way from Milwaukee Wi to Ushuaia

Viking Polaris

Departs
September 19th 2029
Duration
61 nights
From
$54,999
per person, double occupancy
Ports of call: +25 more ports