Main River Cruises

428 itineraries · 87 ships · 14 ports

Main River Cruises: 428 itineraries on 87 ships from 12 cruise lines, ranging from 4 to 34 nights. Ports along the Main River include Aschaffenburg, Eltmann, Frankfurt am Main, Gerlachshausen, Karlstadt am Main and Kitzingen.

Ports on the Main River

Main River Cruises: itineraries

Frankfurt am Main, Germany

8 Days One-Way from Frankfurt Am Main to Nuremberg

SS Emilie

Departs
December 15th 2026
Duration
7 nights
Ports of call: +2 more ports
Frankfurt am Main, Germany

5 Days One-Way from Frankfurt Am Main to Basel

Avalon Tranquility II

Departs
December 16th 2026
Duration
4 nights
From
$3,452
per person, double occupancy
Ports of call:
Amsterdam, Netherlands

16 Days One-Way from Amsterdam to Budapest

APT Ostara

Departs
December 18th 2026
Duration
15 nights
From
$3,698
per person, double occupancy
Ports of call: +7 more ports
Budapest, Hungary

16 Days One-Way from Budapest to Amsterdam

APT Solara

Departs
December 18th 2026
Duration
15 nights
From
$3,698
per person, double occupancy
Ports of call: +7 more ports
Frankfurt am Main, Germany

5 Days One-Way from Frankfurt Am Main to Basel

Avalon Illumination

Departs
December 18th 2026
Duration
4 nights
From
$3,492
per person, double occupancy
Ports of call:
Paris City, France

21 Days One-Way from Paris City to Prague

Scenic Jasper

Departs
December 19th 2026
Duration
20 nights
From
$8,111
per person, double occupancy
Ports of call: +10 more ports
Paris City, France

18 Days One-Way from Paris City to Budapest

Scenic Jasper

Departs
December 19th 2026
Duration
17 nights
From
$7,571
per person, double occupancy
Ports of call: +9 more ports
Prague, Czechia - Czech Republic

18 Days One-Way from Prague to Amsterdam

Scenic Opal

Departs
December 19th 2026
Duration
17 nights
From
$6,363
per person, double occupancy
Ports of call: +7 more ports
Prague, Czechia - Czech Republic

21 Days One-Way from Prague to Paris City

Scenic Opal

Departs
December 19th 2026
Duration
20 nights
From
$8,111
per person, double occupancy
Ports of call: +8 more ports
Frankfurt am Main, Germany

8 Days Frankfurt Am Main, Germany Round Trip

Arosa Clea

Departs
December 20th 2026
Duration
7 nights
From
$1,725
per person, double occupancy
Ports of call:
Paris City, France

21 Days One-Way from Paris City to Prague

Scenic Jade

Departs
December 20th 2026
Duration
20 nights
From
$8,111
per person, double occupancy
Ports of call: +9 more ports
Paris City, France

18 Days One-Way from Paris City to Budapest

Scenic Jade

Departs
December 20th 2026
Duration
17 nights
From
$7,571
per person, double occupancy
Ports of call: +8 more ports

Cruise lines sailing the Main River

Often combined with