Main River Cruises

428 itineraries · 87 ships · 14 ports

Main River Cruises: 428 itineraries on 87 ships from 12 cruise lines, ranging from 4 to 34 nights. Ports along the Main River include Aschaffenburg, Eltmann, Frankfurt am Main, Gerlachshausen, Karlstadt am Main and Kitzingen.

Ports on the Main River

Main River Cruises: itineraries

Budapest, Hungary

15 Days One-Way from Budapest to Amsterdam

Scenic Jade

Departs
November 25th 2026
Duration
14 nights
From
$4,584
per person, double occupancy
Ports of call: +10 more ports
Budapest, Hungary

18 Days One-Way from Budapest to Paris City

Scenic Jade

Departs
November 25th 2026
Duration
17 nights
From
$6,389
per person, double occupancy
Ports of call: +9 more ports
Amsterdam, Netherlands

15 Days One-Way from Amsterdam to Budapest

Scenic Pearl

Departs
November 25th 2026
Duration
14 nights
From
$4,679
per person, double occupancy
Ports of call: +8 more ports
Frankfurt am Main, Germany

8 Days One-Way from Frankfurt Am Main to Nuremberg

SS Elisabeth

Departs
November 25th 2026
Duration
7 nights
Ports of call: +2 more ports
Frankfurt am Main, Germany

8 Days One-Way from Frankfurt Am Main to Forchheim

Arosa Clea

Departs
November 26th 2026
Duration
7 nights
From
$1,534
per person, double occupancy
Ports of call:
Prague, Czechia - Czech Republic

12 Days One-Way from Prague to Basel

Avalon Imagery II

Departs
November 29th 2026
Duration
11 nights
Ports of call: +6 more ports
Prague, Czechia - Czech Republic

8 Days One-Way from Prague to Frankfurt Am Main

Avalon Imagery II

Departs
November 29th 2026
Duration
7 nights
From
$5,317
per person, double occupancy
Ports of call:
Basel, Switzerland

5 Days One-Way from Basel to Frankfurt Am Main

Avalon Panorama

Departs
November 29th 2026
Duration
4 nights
From
$2,993
per person, double occupancy
Ports of call:
Nuremberg, Germany

6 Days One-Way from Nuremberg to Frankfurt Am Main

Avalon Imagery II

Departs
December 1st 2026
Duration
5 nights
Ports of call:
Nuremberg, Germany

10 Days One-Way from Nuremberg to Basel

Avalon Imagery II

Departs
December 1st 2026
Duration
9 nights
Ports of call: +5 more ports
Basel, Switzerland

10 Days One-Way from Basel to Nuremberg

Avalon Tranquility II

Departs
December 2nd 2026
Duration
9 nights
Ports of call: +4 more ports
Basel, Switzerland

12 Days One-Way from Basel to Prague

Avalon Tranquility II

Departs
December 2nd 2026
Duration
11 nights
Ports of call: +5 more ports

Cruise lines sailing the Main River

Often combined with