American Cruise Lines Cruises

176 sailings with American Cruise Lines day-by-day itineraries

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Waterways Cruise is a cruise specialist travel agency that helps clients plan and book American Cruise Lines cruises to Canada, train/bus travel and United States. Our advisors know American Cruise Lines' ships, itineraries and onboard experience first-hand, so you get expert guidance, access to exclusive rates, and one dedicated point of contact from booking through the day you sail.

176 Sailings Found
Amelia Island Florida, United States

9 Days One-Way from Amelia Island Florida to Charleston Sc

ACL American Glory

Departs
November 17th 2026
Duration
8 nights
From
$5,990
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Tampa, United States

9 Days One-Way from Tampa to St Petersburg Fl

ACL American Maverick

Departs
November 17th 2026
Duration
8 nights
From
$6,575
per person, double occupancy
Ports of call:
Tampa, United States

9 Days One-Way from Tampa to St Petersburg Fl

ACL American Pioneer

Departs
November 20th 2026
Duration
8 nights
From
$6,575
per person, double occupancy
Ports of call:

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Jacksonville, United States

9 Days Jacksonville, USA Round Trip

ACL American Eagle

Departs
November 21st 2026
Duration
8 nights
Ports of call:
Charleston SC, United States

9 Days One-Way from Charleston Sc to Amelia Island Florida

ACL American Legend

Departs
November 21st 2026
Duration
8 nights
From
$6,995
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Amelia Island Florida, United States

16 Days One-Way from Amelia Island Florida to St Petersburg Fl

ACL American Patriot

Departs
November 22nd 2026
Duration
15 nights
Ports of call: +3 more ports
Amelia Island Florida, United States

16 Days One-Way from Amelia Island Florida to St Petersburg Fl

ACL American Ranger

Departs
November 22nd 2026
Duration
15 nights
From
$12,360
per person, double occupancy
Ports of call: +4 more ports
Charleston SC, United States

9 Days One-Way from Charleston Sc to Amelia Island Florida

ACL American Glory

Departs
November 24th 2026
Duration
8 nights
From
$5,990
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Amelia Island Florida, United States

9 Days One-Way from Amelia Island Florida to Charleston Sc

ACL American Legend

Departs
November 28th 2026
Duration
8 nights
From
$6,995
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Tampa, United States

9 Days One-Way from Tampa to St Petersburg Fl

ACL American Ranger

Departs
December 6th 2026
Duration
8 nights
From
$6,575
per person, double occupancy
Ports of call:
New Orleans, United States

8 Days New Orleans, USA Round Trip

ACL American Melody

Departs
December 11th 2026
Duration
7 nights
From
$4,255
per person, double occupancy
Ports of call:
New Orleans, United States

8 Days New Orleans, USA Round Trip

ACL American Serenade

Departs
February 13th 2027
Duration
7 nights
From
$4,255
per person, double occupancy
Ports of call:
New Orleans, United States

9 Days One-Way from New Orleans to Memphis Tn

ACL American Serenade

Departs
February 19th 2027
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
New Orleans, United States

9 Days One-Way from New Orleans to Memphis Tn

American Splendor

Departs
February 23rd 2027
Duration
8 nights
From
$4,295
per person, double occupancy
Ports of call: +1 more port
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

ACL American Serenade

Departs
February 26th 2027
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
Amelia Island Florida, United States

9 Days One-Way from Amelia Island Florida to Charleston Sc

ACL American Eagle

Departs
March 19th 2027
Duration
8 nights
From
$5,990
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Portland OR, United States

7 Days Portland Or, USA Round Trip

American Pride

Departs
March 22nd 2027
Duration
6 nights
From
$4,125
per person, double occupancy
Ports of call:
Amelia Island Florida, United States

16 Days One-Way from Amelia Island Florida to Washington Dc

ACL American Legend

Departs
March 24th 2027
Duration
15 nights
From
$11,570
per person, double occupancy
Ports of call: Hilton Head Island SC +6 more ports

Created by the Waterways Cruise content team and reviewed and fact-checked by , Sr. Cruise Travel Agent and Founder of Waterways Cruise.

Published May 16, 2026 · Last updated October 31, 2026

Fares, availability and itineraries change often. Confirm current details with your cruise line or a Waterways Cruise agent before you book.


Cruise Disclosure

Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!