American Cruise Lines Cruises

176 sailings with American Cruise Lines day-by-day itineraries

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Waterways Cruise is a cruise specialist travel agency that helps clients plan and book American Cruise Lines cruises to Canada, train/bus travel and United States. Our advisors know American Cruise Lines' ships, itineraries and onboard experience first-hand, so you get expert guidance, access to exclusive rates, and one dedicated point of contact from booking through the day you sail.

176 Sailings Found
Baltimore, United States

16 Days One-Way from Baltimore to Amelia Island Florida

ACL American Legend

Departs
October 31st 2026
Duration
15 nights
From
$11,570
per person, double occupancy
Ports of call: +6 more ports
Philadelphia, United States

12 Days One-Way from Philadelphia to Washington Dc

ACL American Ranger

Departs
November 1st 2026
Duration
11 nights
From
$9,020
per person, double occupancy
Ports of call: +1 more port
New Orleans, United States

8 Days New Orleans, USA Round Trip

American Heritage

Departs
November 1st 2026
Duration
7 nights
From
$3,630
per person, double occupancy
Ports of call:

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Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

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Clarkston WA, United States

9 Days One-Way from Clarkston Wa to Portland or

American Pride

Departs
November 1st 2026
Duration
8 nights
From
$5,555
per person, double occupancy
Ports of call:
Portland OR, United States

9 Days One-Way from Portland or to Clarkston Wa

ACL American Encore

Departs
November 3rd 2026
Duration
8 nights
From
$7,390
per person, double occupancy
Ports of call: +2 more ports
Baltimore, United States

16 Days One-Way from Baltimore to Amelia Island Florida

ACL American Glory

Departs
November 3rd 2026
Duration
15 nights
From
$9,910
per person, double occupancy
Ports of call: +6 more ports
Clarkston WA, United States

9 Days One-Way from Clarkston Wa to Portland or

ACL American Song

Departs
November 3rd 2026
Duration
8 nights
From
$6,400
per person, double occupancy
Ports of call:
Portland OR, United States

9 Days One-Way from Portland or to Clarkston Wa

ACL American Harmony

Departs
November 6th 2026
Duration
8 nights
From
$6,715
per person, double occupancy
Ports of call: +2 more ports
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

ACL American Melody

Departs
November 6th 2026
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
Amelia Island Florida, United States

9 Days One-Way from Amelia Island Florida to Charleston Sc

ACL American Liberty

Departs
November 9th 2026
Duration
8 nights
From
$6,995
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Clarkston WA, United States

9 Days One-Way from Clarkston Wa to Portland or

ACL American Encore

Departs
November 10th 2026
Duration
8 nights
From
$7,390
per person, double occupancy
Ports of call:
New Orleans, United States

8 Days One-Way from New Orleans to Pensacola Fl

ACL American Symphony

Departs
November 10th 2026
Duration
7 nights
From
$4,565
per person, double occupancy
Ports of call:
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

American Splendor

Departs
November 10th 2026
Duration
8 nights
From
$4,295
per person, double occupancy
Ports of call: +1 more port
Washington DC, United States

9 Days One-Way from Washington Dc to Baltimore

ACL American Ranger

Departs
November 11th 2026
Duration
8 nights
From
$6,575
per person, double occupancy
Ports of call:
New Orleans, United States

9 Days One-Way from New Orleans to Memphis Tn

ACL American Melody

Departs
November 13th 2026
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
Charleston SC, United States

9 Days One-Way from Charleston Sc to Amelia Island Florida

ACL American Eagle

Departs
November 14th 2026
Duration
8 nights
From
$5,990
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Charleston SC, United States

9 Days One-Way from Charleston Sc to Amelia Island Florida

ACL American Liberty

Departs
November 16th 2026
Duration
8 nights
From
$6,995
per person, double occupancy
Ports of call: Hilton Head Island SC +1 more port
Pensacola FL, United States

8 Days One-Way from Pensacola Fl to New Orleans

ACL American Symphony

Departs
November 16th 2026
Duration
7 nights
From
$4,565
per person, double occupancy
Ports of call:

Created by the Waterways Cruise content team and reviewed and fact-checked by , Sr. Cruise Travel Agent and Founder of Waterways Cruise.

Published May 16, 2026 · Last updated October 31, 2026

Fares, availability and itineraries change often. Confirm current details with your cruise line or a Waterways Cruise agent before you book.


Cruise Disclosure

Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!