Cruises from Guayaquil

1 cruise line and 4 ships sailing from Guayaquil, Ecuador

Cruises visiting Guayaquil

Guayaquil is Ecuador’s largest city, a river port where the Guayas meets the Pacific-facing estuary. Start along the Malecón 2000, the broad waterfront promenade lined with gardens, museums and cafés. Then climb the steps of Las Peñas to Santa Ana Hill for rooftop views across the city and river. At Parque Seminario, iguanas roam beneath the palms in the heart of downtown. Guayaquil rewards a curious day ashore with lively streets, colonial-era façades and a distinctly coastal rhythm.

Cruises from Guayaquil, Ecuador

Sailings departing from Guayaquil, earliest departure first.

11 Sailings Found
Guayaquil, Ecuador

8 Days Guayaquil, Ecuador Round Trip

National Geographic Islander 2

Departs
October 31st 2026
Duration
7 nights
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Ports of call: +3 more ports
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Guayaquil, Ecuador

10 Days Guayaquil, Ecuador Round Trip

National Geographic Endeavour 2

Departs
November 6th 2026
Duration
9 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

16 Days One-Way from Guayaquil to Callao-Lima

National Geographic Endeavour 2

Departs
November 6th 2026
Duration
15 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

7 Days Guayaquil, Ecuador Round Trip

National Geographic Islander 2

Departs
November 10th 2026
Duration
6 nights
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Ports of call: +1 more port
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Guayaquil, Ecuador

10 Days Guayaquil, Ecuador Round Trip

National Geographic Delfina

Departs
November 20th 2026
Duration
9 nights
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Ports of call: +5 more ports
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Guayaquil, Ecuador

16 Days One-Way from Guayaquil to Callao-Lima

National Geographic Gemini

Departs
November 27th 2026
Duration
15 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

10 Days Guayaquil, Ecuador Round Trip

National Geographic Gemini

Departs
November 27th 2026
Duration
9 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

16 Days One-Way from Guayaquil to Callao-Lima

National Geographic Islander 2

Departs
April 2nd 2027
Duration
15 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

10 Days Guayaquil, Ecuador Round Trip

National Geographic Islander 2

Departs
April 2nd 2027
Duration
9 nights
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Ports of call: +7 more ports
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Guayaquil, Ecuador

8 Days Guayaquil, Ecuador Round Trip

National Geographic Gemini

Departs
April 3rd 2027
Duration
7 nights
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Ports of call: +3 more ports
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Guayaquil, Ecuador

7 Days Guayaquil, Ecuador Round Trip

National Geographic Gemini

Departs
April 13th 2027
Duration
6 nights
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Ports of call: +1 more port
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Cruise lines embarking (starting) at Guayaquil (1)

Cruise lineCategoryTypeShips departing from Guayaquil
Lindblad Expeditions Premium Expedition National Geographic Delfina, National Geographic Endeavour 2, National Geographic Gemini, National Geographic Islander 2

The complete Waterways Cruise destination guide to Guayaquil, Ecuador →

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Cruise lines
4
Ships departing

Published September 19, 2026