Cruises from San Antonio

6 cruise lines and 7 ships sailing from San Antonio, Chile

Cruises visiting San Antonio

San Antonio is Chile’s largest commercial port, a working coastal city with a distinctly local rhythm. Its appeal extends beyond the docks: Santiago lies about 110 kilometres inland. Valparaíso is north, while the Casablanca Valley’s wineries offer a rewarding excursion nearby. Begin at the fish market and waterfront, or venture to Santiago, Valparaíso and Casablanca’s vineyards.

Cruises from San Antonio, Chile

Sailings departing from San Antonio, earliest departure first.

17 Sailings Found
San Antonio, Chile

31 Days One-Way from San Antonio to Ushuaia

Seabourn Pursuit

Departs
November 12th 2026
Duration
30 nights
From
$27,871
per person, double occupancy
Ports of call: +1 more port
San Antonio, Chile

11 Days One-Way from San Antonio to Ushuaia

Seabourn Pursuit

Departs
November 12th 2026
Duration
10 nights
From
$6,369
per person, double occupancy
Ports of call: +1 more port
San Antonio, Chile

15 Days One-Way from San Antonio to Buenos Aires

ms Oosterdam

Departs
December 4th 2026
Duration
14 nights
From
$2,924
per person, double occupancy
Ports of call: +4 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

San Antonio, Chile

15 Days One-Way from San Antonio to Buenos Aires

Majestic Princess

Departs
December 22nd 2026
Duration
14 nights
From
$2,464
per person, double occupancy
Ports of call: +3 more ports
San Antonio, Chile

22 Days One-Way from San Antonio to Buenos Aires

ms Oosterdam

Departs
January 10th 2027
Duration
21 nights
Ports of call: +3 more ports
San Antonio, Chile

33 Days One-Way from San Antonio to Southampton

Queen Anne

Departs
March 1st 2027
Duration
32 nights
From
$4,769
per person, double occupancy
Ports of call: +5 more ports
Departs
March 1st 2027
Duration
18 nights
From
$3,099
per person, double occupancy
Ports of call: +2 more ports
San Antonio, Chile

36 Days One-Way from San Antonio to Hamburg

Queen Anne

Departs
March 1st 2027
Duration
35 nights
From
$5,429
per person, double occupancy
Ports of call: +7 more ports
San Antonio, Chile

8 Days One-Way from San Antonio to Callao-Lima

Azamara Journey

Departs
March 10th 2027
Duration
7 nights
From
$1,919
per person, double occupancy
Ports of call:
San Antonio, Chile

20 Days One-Way from San Antonio to Miami

Azamara Journey

Departs
March 10th 2027
Duration
19 nights
From
$4,369
per person, double occupancy
Ports of call: +6 more ports
San Antonio, Chile

17 Days One-Way from San Antonio to Fort Lauderdale

ms Oosterdam

Departs
March 24th 2027
Duration
16 nights
From
$2,459
per person, double occupancy
Ports of call: +4 more ports
San Antonio, Chile

20 Days One-Way from San Antonio to Papeete

Seabourn Pursuit

Departs
April 7th 2027
Duration
19 nights
From
$18,553
per person, double occupancy
Ports of call:

Cruise lines embarking (starting) at San Antonio (6)

Cruise lineCategoryTypeShips departing from San Antonio
Seabourn Cruises Ultra Luxury Ocean Seabourn Pursuit
Azamara Cruises Premium Ocean Azamara Journey
Cunard Contemporary Ocean Queen Anne
Holland America Contemporary Ocean ms Nieuw Amsterdam, ms Oosterdam
Norwegian Cruise Line Contemporary Ocean Norwegian Star
Princess Cruises Contemporary Ocean Majestic Princess

The complete Waterways Cruise destination guide to San Antonio, Chile →

6
Cruise lines
7
Ships departing

Published August 25, 2026