Italy Cruise from Milano to Amsterdam — 12 Days

11 nights · Italy · River cruise · Departs Milano (Italy) · Visiting Como, Basel, Kehl-Strasbourg, Heidelberg, Rudesheim am Rhein, Cologne, Amsterdam · Aboard AmaWaterways on the AmaSofia

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Waterways

This river cruise sails the Lake Como and Rhine, departing Milano.

  1. Lake Como →
  2. Rhine
Cruise lineAmaWaterways
ShipAmaSofia
Duration11 nights
Port calls8
Departures1 sailings
Year built2026
Guests156
Cabins76
Crew51
Length135 m
Beam12 m
Cruising speed11.0 kn
  1. Days 1–3

    Milano, Italy

    Milan sits inland in northern Italy, offering a compelling change of pace from the coast. The Duomo’s rooftop terraces reveal a forest of Gothic spires. Nearby, the Galleria Vittorio Emanuele II shelters cafés and boutiques beneath its glass dome. Brera’s galleries and quiet lanes suit an unhurried afternoon. Reserve well ahead to see Leonardo da Vinci’s The Last Supper, one of the city’s defining treasures.

  2. Days 3–4

    Como, Italy

    Como is the southern gateway to Lake Como, where grand villas and Alpine slopes frame the water. From Piazza Cavour, ferries reach villages such as Bellagio and Tremezzo, while the lakeside promenade invites an unhurried start. The old town’s cathedral blends Gothic and Renaissance detail. Nearby, the funicular climbs to Brunate for expansive lake views. Come for the water, then step ashore to discover a compact city with a distinct identity of its own.

    • Land Tour (Land Tour)
    • Land Tour (Land Tour)
  3. Day 5

    Basel, Switzerland

    Basel sits where Switzerland meets France and Germany, with the Rhine running through its centre. A short walk from the river leads to the red-sandstone Rathaus and Münster, whose terraces open across the rooftops. The city rewards unhurried exploring, from medieval lanes in the Old Town to galleries and renowned art collections. Cross the river by ferry, or use Basel’s efficient trams to reach museums, cafés and the lively Marktplatz.

    • Land Tour (Land Tour)
  4. Day 7

    Kehl-Strasbourg, Germany

    Strasbourg rewards visitors with a rare blend of French elegance and German character. Its historic center, the Grande Île, is a UNESCO World Heritage site, threaded with canals and half-timbered houses. At its heart, Strasbourg Cathedral rises above the old streets, its pink sandstone façade a masterpiece of Gothic architecture. Take time for a table of Alsatian cooking, where French technique meets hearty regional tradition. Then follow the riverfront lanes and discover a city shaped by centuries on Europe’s border.

  5. Day 8

    Heidelberg, Germany

    Few German cities make history feel as immediate as Heidelberg. Set beside the Neckar, its old town gathers around the market square and the Church of the Holy Spirit. Cross the Old Bridge for views of the red sandstone castle, rising above the rooftops. Founded in 1386, Heidelberg University gives the city an enduring scholarly spirit. Walk the Philosopher’s Way for a wider view, then linger over the cafés and lanes below.

  6. Day 8

    Rudesheim am Rhein, Germany

    Rüdesheim is a rewarding first stop on the Rhine, with vineyards climbing steep slopes above the water. It stands at the southern gateway to the UNESCO-listed Upper Middle Rhine Valley, famed for castles and dramatic river scenery. Explore the old lanes and Drosselgasse, then take the cable car through the vines to the Niederwald Monument. From its hilltop setting, the Rhine spreads below in a view worth lingering over.

    • Land Tour (Land Tour)
    • Land Tour (Land Tour)
    • Land Tour (Land Tour)
    • Land Tour (Land Tour)
  7. Day 9

    River Cruising (River Cruising)

  8. Day 10

    Cologne, Germany

    Cologne announces itself from the Rhine with the soaring twin spires of its Gothic cathedral. Step ashore to explore a compact old town, Roman remains, and museums holding major works of art. The cathedral, a UNESCO World Heritage site, anchors the city centre. Enjoy Kölsch in a traditional brewery, then cross the river for a view of the skyline.

  9. Days 11–12

    Amsterdam, Netherlands

    Amsterdam pairs world-class museums with the everyday pleasure of canal-side life. Its Golden Age houses, narrow waterways and lively markets make the city rewarding well beyond its famous sights. Visit the Rijksmuseum for Dutch masters, then explore the canal belt on foot or by boat. Leave time for a neighbourhood café: in Amsterdam, the best discoveries often come between the landmarks.

AmaSofia Cruises

Published September 12, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

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