Zurich, Switzerland Cruise from Basel to Frankfurt am Main — 5 Days

4 nights · Zurich, Switzerland · River cruise · Departs Basel (Switzerland) · Visiting Breisach am Rhein, Kehl-Strasbourg, Speyer, Heidelberg, Frankfurt am Main · Aboard Avalon Waterways on the Avalon Vista

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Waterways

This river cruise sails the Rhine and Main, departing Basel.

  1. Rhine →
  2. Main
Cruise lineAvalon Waterways
ShipAvalon Vista
Duration4 nights
Port calls6
Departures1 sailings
From fare$4,500 per person
Year built2012
Guests166
Cabins84
Crew47
Length135 m
Beam12 m
Cruising speed12.0 kn
  1. Day 1

    Basel, Switzerland

    Basel sits where Switzerland meets France and Germany, with the Rhine running through its centre. A short walk from the river leads to the red-sandstone Rathaus and Münster, whose terraces open across the rooftops. The city rewards unhurried exploring, from medieval lanes in the Old Town to galleries and renowned art collections. Cross the river by ferry, or use Basel’s efficient trams to reach museums, cafés and the lively Marktplatz.

  2. Day 2

    Breisach am Rhein, Germany

    Breisach rewards a short walk uphill: its old town gathers around St. Stephen’s Minster, above the Rhine. Inside, the minster’s carved altar and medieval murals offer a close encounter with Upper Rhine art. Across the river lies Alsace; inland, the Kaiserstuhl’s volcanic slopes are known for vineyards and distinctive wines. Allow time for the compact center and its river views; Breisach makes a rewarding pause between Freiburg and Colmar.

    • Land Tour (Land Tour)
    • Schwarzwald (Ask Travel Agent)
    • Land Tour (Land Tour)
  3. Day 3

    Kehl-Strasbourg, Germany

    Strasbourg rewards visitors with a rare blend of French elegance and German character. Its historic center, the Grande Île, is a UNESCO World Heritage site, threaded with canals and half-timbered houses. At its heart, Strasbourg Cathedral rises above the old streets, its pink sandstone façade a masterpiece of Gothic architecture. Take time for a table of Alsatian cooking, where French technique meets hearty regional tradition. Then follow the riverfront lanes and discover a city shaped by centuries on Europe’s border.

  4. Day 4

    Speyer, Germany

    Speyer’s red-sandstone cathedral dominates a historic city on the Rhine. Begun in 1030 under Emperor Conrad II, it is among Europe’s finest Romanesque churches and a UNESCO World Heritage Site. Its vast crypt holds the tombs of German emperors and kings. Beyond the cathedral, explore the old town’s lively squares and medieval Jewish heritage. The Technik Museum offers an unexpected finale, with historic aircraft and spacecraft on display.

  5. Day 4

    Heidelberg, Germany

    Few German cities make history feel as immediate as Heidelberg. Set beside the Neckar, its old town gathers around the market square and the Church of the Holy Spirit. Cross the Old Bridge for views of the red sandstone castle, rising above the rooftops. Founded in 1386, Heidelberg University gives the city an enduring scholarly spirit. Walk the Philosopher’s Way for a wider view, then linger over the cafés and lanes below.

  6. Day 4

    Speyer, Germany

    Speyer’s red-sandstone cathedral dominates a historic city on the Rhine. Begun in 1030 under Emperor Conrad II, it is among Europe’s finest Romanesque churches and a UNESCO World Heritage Site. Its vast crypt holds the tombs of German emperors and kings. Beyond the cathedral, explore the old town’s lively squares and medieval Jewish heritage. The Technik Museum offers an unexpected finale, with historic aircraft and spacecraft on display.

    • Land Tour (Land Tour)
    • Land Tour (Land Tour)
  7. Day 5

    Frankfurt am Main, Germany

    Frankfurt am Main pairs a striking skyline with the River Main and a compact historic centre. Begin at Römerberg, where half-timbered façades frame the city’s medieval square. Then cross the river to the Städel Museum, one of Germany’s leading art museums. The city rewards a longer stay. Explore the Museumsufer and sample Apfelwein in Sachsenhausen. Here, Europe’s financial capital balances modern ambition with old-world character.

Avalon Vista Cruises

Published September 22, 2026
Last updated October 3, 2026
Author: J. Richard


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