Crystal Cruises

Crystal Serenity

Ocean Cruise Ship

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Crystal Serenity Itineraries & Sailings

Upcoming sailings on Crystal Serenity, earliest departure first.

91 Sailings Found
Buenos Aires, Argentina

18 Days One-Way from Buenos Aires to Valparaiso-Santiago

Crystal Serenity

Departs
November 11th 2027
Duration
17 nights
From
$10,300
per person, double occupancy
Ports of call: +5 more ports
Valparaiso-Santiago, Chile

24 Days One-Way from Valparaiso-Santiago to Fort Lauderdale

Crystal Serenity

Departs
November 29th 2027
Duration
23 nights
From
$10,180
per person, double occupancy
Ports of call: +10 more ports
Valparaiso-Santiago, Chile

12 Days One-Way from Valparaiso-Santiago to Panama City

Crystal Serenity

Departs
November 29th 2027
Duration
11 nights
From
$5,920
per person, double occupancy
Ports of call: +2 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Panama City, Panama

11 Days One-Way from Panama City to Fort Lauderdale

Crystal Serenity

Departs
December 12th 2027
Duration
10 nights
From
$5,070
per person, double occupancy
Ports of call: +3 more ports
Fort Lauderdale, United States

8 Days One-Way from Fort Lauderdale to San Juan

Crystal Serenity

Departs
December 22nd 2027
Duration
7 nights
From
$3,700
per person, double occupancy
Ports of call:
Fort Lauderdale, United States

18 Days Fort Lauderdale, USA Round Trip

Crystal Serenity

Departs
December 22nd 2027
Duration
17 nights
From
$9,200
per person, double occupancy
Ports of call: +7 more ports
San Juan, Puerto Rico

11 Days One-Way from San Juan to Fort Lauderdale

Crystal Serenity

Departs
December 29th 2027
Duration
10 nights
From
$5,700
per person, double occupancy
Ports of call: +3 more ports
Fort Lauderdale, United States

11 Days Fort Lauderdale, USA Round Trip

Crystal Serenity

Departs
January 8th 2028
Duration
10 nights
From
$5,300
per person, double occupancy
Ports of call:
Fort Lauderdale, United States

26 Days Fort Lauderdale, USA Round Trip

Crystal Serenity

Departs
January 18th 2028
Duration
25 nights
From
$12,900
per person, double occupancy
Ports of call: +7 more ports
Fort Lauderdale, United States

27 Days Fort Lauderdale, USA Round Trip

Crystal Serenity

Departs
February 12th 2028
Duration
27 nights
From
$13,000
per person, double occupancy
Ports of call: +14 more ports
Fort Lauderdale, United States

18 Days One-Way from Fort Lauderdale to Cartagena Colombia

Crystal Serenity

Departs
February 12th 2028
Duration
17 nights
From
$8,000
per person, double occupancy
Ports of call: +8 more ports
San Juan, Puerto Rico

11 Days One-Way from San Juan to Cartagena Colombia

Crystal Serenity

Departs
February 19th 2028
Duration
10 nights
From
$5,300
per person, double occupancy
Ports of call: +3 more ports