Crystal Cruises

Crystal Serenity

Ocean Cruise Ship

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Crystal Serenity Itineraries & Sailings

Upcoming sailings on Crystal Serenity, earliest departure first.

91 Sailings Found
Lisbon, Portugal

16 Days One-Way from Lisbon to Fort Lauderdale

Crystal Serenity

Departs
November 8th 2026
Duration
15 nights
From
$7,700
per person, double occupancy
Ports of call: +2 more ports
Fort Lauderdale, United States

29 Days One-Way from Fort Lauderdale to San Diego

Crystal Serenity

Departs
November 23rd 2026
Duration
28 nights
Ports of call: +13 more ports
Fort Lauderdale, United States

20 Days One-Way from Fort Lauderdale to Puntarenas

Crystal Serenity

Departs
November 23rd 2026
Duration
19 nights
Ports of call: +7 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Fort Lauderdale, United States

9 Days One-Way from Fort Lauderdale to Cartagena Colombia

Crystal Serenity

Departs
November 23rd 2026
Duration
8 nights
Ports of call: +1 more port
Fort Lauderdale, United States

5 Days One-Way from Fort Lauderdale to San Juan

Crystal Serenity

Departs
November 23rd 2026
Duration
4 nights
From
$1,980
per person, double occupancy
Ports of call:
San Juan, Puerto Rico

5 Days One-Way from San Juan to Cartagena Colombia

Crystal Serenity

Departs
November 27th 2026
Duration
4 nights
From
$3,000
per person, double occupancy
Ports of call:
Cartagena Colombia, Colombia

11 Days One-Way from Cartagena Colombia to Puntarenas

Crystal Serenity

Departs
December 2nd 2026
Duration
10 nights
From
$5,050
per person, double occupancy
Ports of call: +2 more ports
Puntarenas, Costa Rica

10 Days One-Way from Puntarenas to San Diego

Crystal Serenity

Departs
December 12th 2026
Duration
9 nights
From
$4,560
per person, double occupancy
Ports of call: +1 more port
San Diego, United States

19 Days San Diego, USA Round Trip

Crystal Serenity

Departs
December 21st 2026
Duration
18 nights
Ports of call: +2 more ports
San Diego, United States

10 Days San Diego, USA Round Trip

Crystal Serenity

Departs
December 21st 2026
Duration
9 nights
From
$6,200
per person, double occupancy
Ports of call:
San Diego, United States

31 Days One-Way from San Diego to Papeete

Crystal Serenity

Departs
January 8th 2027
Duration
30 nights
From
$17,000
per person, double occupancy
Ports of call: +11 more ports
San Diego, United States

16 Days One-Way from San Diego to Callao-Lima

Crystal Serenity

Departs
January 8th 2027
Duration
15 nights
From
$8,300
per person, double occupancy
Ports of call: +5 more ports