Sicily Italy Cruise from Palermo — 8 Days

7 nights · Sicily Italy · Departs Palermo (Italy) · Visiting Valletta, Barcelona, Marseille, Genoa, Naples · Aboard MSC Cruises on the MSC Seashore

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Cruise lineMSC Cruises
ShipMSC Seashore
Duration7 nights
Port calls6
Departures19 sailings
From fare$1,078 per person
Year built2021
Guests5877
Cabins2270
Crew1648
Length339 m
Beam41 m
Cruising speed22.0 kn
  1. Day 1

    Palermo, Italy

    Palermo rewards curious travellers with a vivid mix of Arab-Norman architecture, lively markets and Sicilian cooking. Start at the cathedral, where Norman, Gothic and Baroque details reflect the city’s layered past. Then walk through the Capo market or visit the Palatine Chapel, famed for its Byzantine mosaics. Leave time for pasta con le sarde or arancini; Palermo’s strongest impressions often arrive at the table.

  2. Day 2

    Valletta, Malta

    Valletta makes a powerful first impression, its honey-coloured walls rising above Grand Harbour. Founded by the Knights of St John in 1566, Malta’s compact capital rewards exploration on foot. Enter St John’s Co-Cathedral for Caravaggio’s monumental paintings, then follow Republic Street to cafés, palaces and the Upper Barrakka Gardens. From the terraces, watch ferries cross the harbour and look towards the Three Cities. Allow time for steep lanes and quiet side streets.

  3. Day 4

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

  4. Day 5

    Marseille, France

    Marseille is France’s oldest city, founded by Greek settlers around 600 BC, and it still faces the Mediterranean with confidence. Begin at the Vieux-Port, where fishing boats share the waterfront with cafés and ferries bound for nearby islands. Climb to Notre-Dame de la Garde for sweeping views, or explore Le Panier’s narrow lanes and lively squares. The Calanques’ limestone coves lie beyond the city; local markets bring Provençal flavors closer.

  5. Day 6

    Genoa, Italy

    Genoa is a city shaped by the sea, with a busy port framed by hills and centuries of trade. In the old town, narrow caruggi lead to grand squares and Romanesque churches. The Palazzi dei Rolli, a UNESCO-listed group of aristocratic residences, reveal the city’s former wealth. Walk the restored Porto Antico, then sit down to basil-scented pesto or freshly caught seafood. Genoa rewards those who explore on foot.

  6. Day 7

    Naples, Italy

    Naples puts its history within reach: the port opens onto a compact city framed by Mount Vesuvius and the bay. UNESCO-listed streets lead to churches, palaces and the everyday theatre of southern Italian life. At the National Archaeological Museum, mosaics and objects from Pompeii and Herculaneum bring the Roman world sharply into focus. Stay close for Neapolitan pizza, or use Naples as a springboard to Pompeii, Herculaneum and Capri.

  7. Day 8

    Palermo, Italy

    Palermo rewards curious travellers with a vivid mix of Arab-Norman architecture, lively markets and Sicilian cooking. Start at the cathedral, where Norman, Gothic and Baroque details reflect the city’s layered past. Then walk through the Capo market or visit the Palatine Chapel, famed for its Byzantine mosaics. Leave time for pasta con le sarde or arancini; Palermo’s strongest impressions often arrive at the table.

MSC Seashore Cruises

Published August 16, 2026
Last updated October 3, 2026
Author: J. Richard


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