HX Expeditions

MV Santa Cruz II Galapagos

Expedition Cruise Ship | Mega Yacht Class

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MV Santa Cruz II Galapagos Itineraries & Sailings

Upcoming sailings on MV Santa Cruz II Galapagos, earliest departure first.

8 Sailings Found
Quito, Ecuador

7 Days Quito, Ecuador Round Trip

MV Santa Cruz II Galapagos

Departs
October 31st 2026
Duration
6 nights
From
$3,952
per person, double occupancy
Quito, Ecuador

9 Days One-Way from Quito to Guayaquil

MV Santa Cruz II Galapagos

Departs
November 4th 2026
Duration
8 nights
From
$4,795
per person, double occupancy
Callao-Lima, Peru

16 Days One-Way from Callao-Lima to Guayaquil

MV Santa Cruz II Galapagos

Departs
November 5th 2026
Duration
15 nights
From
$7,279
per person, double occupancy

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Callao-Lima, Peru

12 Days One-Way from Callao-Lima to Quito

MV Santa Cruz II Galapagos

Departs
November 5th 2026
Duration
11 nights
From
$4,226
per person, double occupancy
Quito, Ecuador

11 Days One-Way from Quito to Guayaquil

MV Santa Cruz II Galapagos

Departs
November 10th 2026
Duration
10 nights
From
$7,279
per person, double occupancy
Quito, Ecuador

7 Days One-Way from Quito to Guayaquil

MV Santa Cruz II Galapagos

Departs
November 10th 2026
Duration
6 nights
From
$4,226
per person, double occupancy
Callao-Lima, Peru

14 Days One-Way from Callao-Lima to Quito

MV Santa Cruz II Galapagos

Departs
November 13th 2026
Duration
13 nights
From
$4,795
per person, double occupancy
Ports of call: +6 more ports
Callao-Lima, Peru

14 Days One-Way from Callao-Lima to Guayaquil

MV Santa Cruz II Galapagos

Departs
February 5th 2027
Duration
13 nights
From
$5,366
per person, double occupancy