15 nights · California · Departs San Diego (USA) · Visiting Puerto Vallarta, Puerto Quetzal, Puntarenas, Panama Canal, Cartagena Colombia, Grand Cayman Island, Tampa · Aboard Royal Caribbean on the Serenade Of The Seas
Image courtesy of Royal Caribbean ©
| Cruise line | Royal Caribbean |
|---|---|
| Ship | Serenade Of The Seas |
| Duration | 15 nights |
| Port calls | 8 |
| Departures | 1 sailings |
| From fare | $1,947 per person |
| Year built | 2003 |
| Guests | 2578 |
| Cabins | 1074 |
| Crew | 859 |
| Length | 293 m |
| Beam | 39 m |
| Cruising speed | 25.0 kn |
San Diego makes an easy first impression: a working harbor, sunlit waterfront and Pacific air. From the cruise terminal, the USS Midway Museum and lively Embarcadero are close at hand. Balboa Park brings world-class museums, gardens and the San Diego Zoo together in one grand setting. In the Gaslamp Quarter, Victorian façades frame restaurants and bars. Nearby neighborhoods reveal Mexican heritage and coastal ease.
Puerto Vallarta sits between the Sierra Madre mountains and Banderas Bay. That setting brings jungle-clad slopes, broad beaches and memorable Pacific views. Begin in the historic center, where cobbled streets lead to the landmark Church of Our Lady of Guadalupe. Follow the Malecón, a seafront promenade lined with sculptures, cafés and galleries. For a taste of the coast, settle in for fresh seafood and watch the bay.
Puerto Quetzal is Guatemala’s Pacific gateway, a working port backed by volcanic highlands. Most visitors head inland to Antigua, where cobbled streets, pastel façades and church ruins preserve a distinctive colonial setting. The drive takes roughly 90 minutes, depending on traffic. Closer to the coast, excursions visit fishing villages and black-sand beaches. Choose Antigua for architecture and history, or stay coastal for a closer look at everyday life in Guatemala.
Step ashore in Puntarenas, Costa Rica’s long, narrow port city on the Pacific coast. From here, rainforest reserves, coffee country and the Nicoya Peninsula lie within reach. Walk the waterfront promenade for seafood and views across the Gulf of Nicoya. Or head inland to Monteverde’s cloud forest. Plan one excursion and allow time for the road; Puntarenas is best enjoyed at an unhurried pace.
Few journeys change your sense of scale like a passage through the Panama Canal. This 50-mile waterway links the Atlantic and Pacific, lifting ships through locks and across Gatun Lake. Watch the gates close, water rise, and a vast vessel move within inches of concrete walls. On deck, the engineering is the spectacle; beyond it, rainforest edges the route. Bring binoculars, and stay outside for the crossing.
A short ride from Cartagena’s cruise port brings you to its UNESCO-listed historic centre and handsome colonial streets. Inside the old walls, flower-draped balconies, shaded plazas and broad stone lanes lead to cafés, churches and lively markets. Visit Castillo San Felipe de Barajas, the great fortress built to defend the harbor, then explore colorful Getsemaní. Come early, before the midday heat settles over the plazas, and save time for a cool drink beside the Caribbean.
Grand Cayman pairs clear water with an easy blend of beach and town. Ships anchor offshore; tenders land in George Town, near duty-free shops, cafés and the Cayman Islands National Museum. Boat trips reach Stingray City, where visitors can encounter southern stingrays in shallow water. Beyond town, Seven Mile Beach is known for pale sand and turquoise water. Choose a beach transfer, an island tour or time in town; Grand Cayman makes a relaxed, rewarding call.
Tampa puts a lively waterfront and a rich slice of Florida history within easy reach of its cruise port. Walk the Riverwalk past the Florida Aquarium and downtown museums. Then explore Ybor City, where brick streets and old cigar factories reflect Cuban, Spanish and Italian immigrant heritage. Before sailing, pause beside Tampa Bay, whose wide, sunlit waters frame the city.
Published September 20, 2026
Last updated October 3, 2026
Author: J. Richard
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