Spain Cruise from Barcelona to Venice — 21 Days

20 nights · Spain · Departs Barcelona (Spain) · Visiting Palamos, Sete, Villefranche-sur-Mer, Monte Carlo, Portofino, La Spezia, Livorno, Golfo Aranci, Civitavecchia-Rome, Salerno, Palermo, Catania, Katakolon, Corfu Island, Kotor, Venice · Aboard Regent Seven Seas Cruises on the Seven Seas Explorer

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Explorer
Duration20 nights
Port calls17
Departures1 sailings
From fare$45,198 per person
Year built2016
Guests829
Cabins375
Crew552
Length224 m
Beam31 m
Cruising speed22.0 kn
  1. Day 1

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

  2. Day 2

    Palamos, Spain

    Palamós brings you to the heart of Spain’s Costa Brava, where a working fishing port meets a handsome old town. Its waterfront is famed for the prawns landed here, best sampled at a local table. Walk the promenade, visit the Fishing Museum, or follow coastal paths towards rocky coves and clear water. Girona and medieval villages lie inland, but Palamós rewards a slower day close to the sea.

  3. Day 3

    Sete, France

    Sète is France’s working Mediterranean port, set between the sea and the vast Étang de Thau. Canals cross the centre, alongside fishing boats, cafés and a covered market. Ride or walk up Mont Saint-Clair for broad views across the harbour, lagoons and coast. Sample oysters from nearby Bouzigues or choose the day’s catch at a port-side restaurant. Museums honour poet Paul Valéry and singer Georges Brassens, both born here, adding cultural depth to this lively port.

  4. Day 4

    Villefranche-sur-Mer, France

    Villefranche-sur-Mer makes an unusually graceful first impression: pastel houses rise above one of the Riviera’s deepest natural harbors. Wander the old town’s narrow lanes, then visit the 16th-century citadel and its museums. Jean Cocteau’s painted Chapel of Saint-Pierre adds a distinctive local detail. Nearby trains connect you with Nice; roads lead to Èze and the wider Côte d’Azur.

  5. Day 5

    Monte Carlo, Monaco

    Monte Carlo makes a striking first impression, with superyachts in Port Hercule and the Alps rising behind the coast. A short walk leads to Casino Square, where Belle Époque architecture frames the famous casino and designer boutiques. For a quieter contrast, climb to Monaco-Ville for the Prince’s Palace, cathedral and views across the harbor. The principality is compact and easy to explore on foot, though its steep streets reward comfortable shoes.

  6. Day 7

    Portofino, Italy

    Portofino is a small Ligurian harbour, framed by green hills and pastel façades. On its crescent waterfront, fishing boats share the view with polished yachts. From the piazzetta, lanes climb to Castello Brown, a former fortress overlooking the harbour and coast. Walk on to the lighthouse at Punta del Capo, or take a boat to nearby Santa Margherita Ligure. A table by the water offers the best reason to linger.

  7. Day 8

    La Spezia, Italy

    La Spezia sits at the head of the Gulf of Poets. Here, Liguria’s steep hills meet a sheltered stretch of Mediterranean coast. Its working harbor gives the city a lively maritime character, while cafés and broad streets reward an easy stroll. Trains connect La Spezia with the villages of the Cinque Terre; ferries sail to Portovenere. Allow time for the city itself, not just its celebrated neighbors.

  8. Day 9

    Livorno, Italy

    Livorno rewards those who look beyond the cruise terminal. Its canals, built in the style of Venice, wind through historic Venezia Nuova. The seafront promenade leads to Terrazza Mascagni, where black-and-white paving frames the sea. At Mercato Centrale, locals shop beneath a vast iron-and-glass roof. Try cacciucco, the city’s rich fish stew. Florence and Pisa are within reach, but Livorno merits time of its own.

  9. Day 10

    Golfo Aranci, Italy

    Golfo Aranci puts northeastern Sardinia within easy reach, with Olbia about 15 kilometres inland and the Costa Smeralda farther north. Yet this working ferry town rewards a slower start: its waterfront, small harbour and clear-water beaches are close at hand. The marine reserve around Tavolara and Molara makes boat excursions a compelling choice, especially for swimmers and snorkellers. Come ashore for northern Sardinia’s pleasures, then choose a beach, a boat trip or a drive towards the coast.

  10. Day 12

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  11. Day 13

    Salerno, Italy

    Salerno puts southern Italy within easy reach, with ferries and roads leading toward the Amalfi Coast. Yet the city rewards a closer look: its old lanes gather around the handsome Duomo di San Matteo. Inside, bronze doors and a richly decorated crypt recall Salerno’s medieval importance as a center of learning. Climb to Arechi Castle for broad views across the Gulf, or venture inland to the Greek temples at Paestum.

  12. Day 14

    Palermo, Italy

    Palermo rewards curious travellers with a vivid mix of Arab-Norman architecture, lively markets and Sicilian cooking. Start at the cathedral, where Norman, Gothic and Baroque details reflect the city’s layered past. Then walk through the Capo market or visit the Palatine Chapel, famed for its Byzantine mosaics. Leave time for pasta con le sarde or arancini; Palermo’s strongest impressions often arrive at the table.

  13. Day 15

    Catania, Italy

    Mount Etna sets the scale in Catania, where black lava stone gives the Sicilian city a character unlike any other. Rebuilt after the 1693 earthquake, its Baroque heart is part of the UNESCO-listed Val di Noto. Begin at Piazza del Duomo, then follow Via Etnea toward cafés, churches and views of the volcano. At La Pescheria, the fish market, Sicily’s daily life is on full display, best sampled before lunch.

  14. Day 17

    Katakolon, Greece

    Katakolon is a compact seaside port on the western Peloponnese, with cafés and shops lining its waterfront. Most visitors come for ancient Olympia, about 35 kilometres inland and readily reached by road. There, the sanctuary, archaeological museum and ancient stadium bring the story of the Olympic Games into focus. Back in Katakolon, allow time for a stroll along the harbour before returning to your ship.

  15. Day 18

    Corfu Island, Greece

    Corfu rewards visitors who look beyond the beach resorts. Its Old Town, a UNESCO World Heritage site, bears the marks of centuries of Venetian rule. Walk the arcaded Liston, then climb to the Old Fortress for views across the rooftops and Ionian Sea. Beyond town, cypress-lined roads lead to Paleokastritsa’s coves, while the Achilleion palace recalls an imperial past. Allow time for lunch; Corfiot cooking pairs Ionian seafood with Italian and Greek influences.

  16. Day 19

    Kotor, Montenegro

    At the head of Montenegro’s Bay of Kotor, the old town sits beneath steep mountains. Enter through the Sea Gate and follow stone lanes to St Tryphon’s Cathedral. Venetian-era walls frame squares, churches, and cafés within a compact UNESCO-listed center. For a broader view, climb toward San Giovanni Fortress; the steps are demanding. Take water and allow time for the ascent, especially in summer heat. From the harbor, the bay’s changing light makes a memorable arrival and departure.

  17. Day 21

    Venice, Italy

    Arrive in Venice by water, where the lagoon’s canals replace ordinary streets. St Mark’s Basilica and Doge’s Palace anchor the celebrated Piazza San Marco. Take a vaporetto along the Grand Canal, then explore a quieter neighborhood on foot. Confirm your ship’s terminal and transfer arrangements before setting out; cruise access varies. Near Rialto, the market and bridge offer a lively glimpse of the city’s trade. Give yourself time to leave the main routes and follow smaller canals.

Seven Seas Explorer Cruises

Published August 28, 2026
Last updated October 3, 2026
Author: J. Richard


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