South Africa Cruise from Cape Town to Port Louis — 15 Days

14 nights · South Africa · Departs Cape Town · Visiting Port Elizabeth, Durban, Mamoudzou, Nosy Be Island, Antsiranana, Port Louis · Aboard Regent Seven Seas Cruises on the Seven Seas Voyager

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Voyager
Duration14 nights
Port calls7
Departures1 sailings
From fare$33,698 per person
Year built2003
Guests777
Cabins353
Crew447
Length206 m
Beam29 m
Cruising speed20.0 kn
  1. Day 1

    Cape Town

    Few ports make a first impression like Cape Town, where Table Mountain rises above a working harbor and the Atlantic. From the waterfront, you can reach the city’s museums, gardens and historic quarters within minutes. Ride the cableway to the summit, or follow the coast toward the Cape Peninsula’s beaches and vineyards. Look beyond the views: Cape Town’s layered history and lively food scene reward a slower visit.

  2. Day 3

    Port Elizabeth

    Port Elizabeth, now officially Gqeberha, faces Algoa Bay in South Africa’s Eastern Cape. See the city’s maritime past at Donkin Reserve, then follow Route 67’s public art and heritage landmarks. Long beaches invite a coastal walk, while Addo Elephant National Park is within easy driving distance. Choose a wildlife excursion or time beside the water; both offer a rewarding introduction to this coastal city.

  3. Day 6

    Durban

    Durban meets the Indian Ocean on South Africa’s east coast, with long beaches and cosmopolitan energy. Along the Golden Mile, the beachfront promenade offers a bracing walk and views of Moses Mabhida Stadium. Try bunny chow, the city’s celebrated curry-filled bread, then browse spices and crafts at Victoria Street Market. Durban’s Zulu heritage and Indian influence give the city a character—and a cuisine—well worth exploring.

  4. Day 11

    Mamoudzou, France

    Mamoudzou is Mayotte’s lively capital, set on Grande-Terre beside the Mozambique Channel. The covered market offers a first look at island life, with spices, tropical produce and handmade goods. From the harbor, ferries cross to Petite-Terre, home to volcanic Lake Dziani and the island’s airport. Back in town, explore on foot and pause over a meal shaped by French and Comorian traditions. Mayotte rewards curiosity with warm hospitality, vivid color and an unhurried pace.

  5. Day 12

    Nosy Be Island, Madagascar

    Nosy Be is Madagascar’s fragrant island, where ylang-ylang plantations scent the air and the Indian Ocean sets the pace. Hell-Ville, its port town, offers a lively market, colonial-era streets and a glimpse of daily Malagasy life. Beyond town, follow the coast to palm-fringed beaches, or take a boat to Nosy Komba and Nosy Tanikely. Come for warm water, volcanic landscapes and wildlife found nowhere else.

  6. Day 13

    Antsiranana, Madagascar

    Antsiranana curves around a vast natural harbour, with Madagascar’s northern headland rising beyond the waterfront. Once known as Diego Suarez, the city retains traces of French rule in its shaded streets and colonial-era buildings. Beyond the waterfront, the Three Bays open onto pale sand and clear water. Inland, the Red Tsingy’s sculpted formations make a striking detour. For cooler air and rainforest trails, head to Montagne d’Ambre National Park, home to waterfalls and distinctive wildlife.

  7. Day 15

    Port Louis, Mauritius

    Port Louis brings Mauritius into focus: a working harbour, a lively market and green volcanic peaks behind the city. Start at Central Market, where vendors sell tropical fruit, spices and street food. Nearby, the Blue Penny Museum traces the island’s maritime and postal history. Fort Adelaide rewards the climb with broad harbour views. Allow time for the waterfront’s restaurants and shops; this is a port best explored on foot.

Seven Seas Voyager Cruises

Published August 31, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!