Mekong River Cruises

99 itineraries · 15 ships · 17 ports

Mekong River Cruises: 99 itineraries on 15 ships from 10 cruise lines, ranging from 7 to 27 nights. Ports along the Mekong River include Angkor Ban, Bến Tre, Cái Bè, Châu Đốc, Cho Gao and Cu Lao Gieng Island Vietnam.

Ports on the Mekong River

Mekong River Cruises: itineraries

Hanoi, Vietnam

14 Days One-Way from Hanoi to Phnom Penh

Avalon Saigon

Departs
November 6th 2026
Duration
13 nights
Ports of call: +3 more ports
Hanoi, Vietnam

15 Days One-Way from Hanoi to Saigon

Viking Tonle

Departs
November 6th 2026
Duration
14 nights
Ports of call: +2 more ports
flight

15 Days Flight Round Trip

APT Mekong Serenity

Departs
November 7th 2026
Duration
14 nights
From
$4,995
per person, double occupancy
Ports of call: +1 more port
Phnom Penh, Cambodia

8 Days One-Way from Phnom Penh to Saigon

Emerald Harmony

Departs
November 7th 2026
Duration
7 nights
From
$4,795
per person, double occupancy
Ports of call: +4 more ports
Hanoi, Vietnam

14 Days One-Way from Hanoi to Siem Reap

RV Indochine

Departs
November 7th 2026
Duration
13 nights
From
$4,431
per person, double occupancy
Ports of call: +4 more ports
Siem Reap, Cambodia

9 Days One-Way from Siem Reap to Saigon

RV Indochine II

Departs
November 7th 2026
Duration
8 nights
From
$2,193
per person, double occupancy
Ports of call:
Saigon, Vietnam

9 Days One-Way from Saigon to Siem Reap

RV Toum Tiou II

Departs
November 8th 2026
Duration
8 nights
From
$1,595
per person, double occupancy
Ports of call: +2 more ports
Saigon, Vietnam

11 Days One-Way from Saigon to Siem Reap

RV Toum Tiou II

Departs
November 8th 2026
Duration
10 nights
From
$2,190
per person, double occupancy
Ports of call: +2 more ports
Siem Reap, Cambodia

8 Days One-Way from Siem Reap to Saigon

AmaDara

Departs
November 9th 2026
Duration
7 nights
From
$2,029
per person, double occupancy
Ports of call: +4 more ports
flight

27 Days Flight Round Trip

APT Mekong Serenity

Departs
November 9th 2026
Duration
26 nights
From
$10,395
per person, double occupancy
Ports of call: +5 more ports
Saigon, Vietnam

16 Days One-Way from Saigon to Laem Chabang

Avalon Saigon

Departs
November 9th 2026
Duration
15 nights
From
$6,524
per person, double occupancy
Ports of call: +3 more ports
Saigon, Vietnam

11 Days One-Way from Saigon to Phnom Penh

Avalon Saigon

Departs
November 9th 2026
Duration
10 nights
Ports of call: +1 more port

Cruise lines sailing the Mekong River

Often combined with