Mekong River Cruises

99 itineraries · 15 ships · 17 ports

Mekong River Cruises: 99 itineraries on 15 ships from 10 cruise lines, ranging from 7 to 27 nights. Ports along the Mekong River include Angkor Ban, Bến Tre, Cái Bè, Châu Đốc, Cho Gao and Cu Lao Gieng Island Vietnam.

Ports on the Mekong River

Mekong River Cruises: itineraries

Siem Reap, Cambodia

15 Days One-Way from Siem Reap to Saigon

Emerald Harmony

Departs
December 16th 2026
Duration
14 nights
From
$4,995
per person, double occupancy
Ports of call: +4 more ports
Hanoi, Vietnam

23 Days One-Way from Hanoi to Siem Reap

Emerald Harmony

Departs
December 18th 2026
Duration
22 nights
From
$6,445
per person, double occupancy
Ports of call: +8 more ports
Phnom Penh, Cambodia

10 Days One-Way from Phnom Penh to Saigon

Emerald Harmony

Departs
December 19th 2026
Duration
9 nights
From
$4,845
per person, double occupancy
Ports of call: +3 more ports
Saigon, Vietnam

15 Days One-Way from Saigon to Siem Reap

Emerald Harmony

Departs
December 26th 2026
Duration
14 nights
From
$4,745
per person, double occupancy
Ports of call: +4 more ports
Saigon, Vietnam

10 Days One-Way from Saigon to Phnom Penh

Emerald Harmony

Departs
December 28th 2026
Duration
9 nights
From
$4,595
per person, double occupancy
Ports of call: +3 more ports
Hanoi, Vietnam

19 Days One-Way from Hanoi to Saigon

Emerald Harmony

Departs
December 30th 2026
Duration
18 nights
From
$6,245
per person, double occupancy
Ports of call: +6 more ports
Saigon, Vietnam

8 Days One-Way from Saigon to Siem Reap

AmaKaia

Departs
January 4th 2027
Duration
7 nights
Ports of call: +5 more ports
Hanoi, Vietnam

14 Days One-Way from Hanoi to Saigon

Aqua Mekong

Departs
January 4th 2027
Duration
13 nights
From
$10,190
per person, double occupancy
Ports of call:
Saigon, Vietnam

13 Days One-Way from Saigon to Siem Reap

Scenic Spirit

Departs
January 10th 2027
Duration
12 nights
Ports of call: +4 more ports
Saigon, Vietnam

11 Days One-Way from Saigon to Siem Reap

Scenic Spirit

Departs
January 12th 2027
Duration
10 nights
Ports of call: +4 more ports
Siem Reap, Cambodia

13 Days One-Way from Siem Reap to Saigon

RV Jahan

Departs
January 13th 2027
Duration
12 nights
From
$14,500
per person, double occupancy
Ports of call: +4 more ports
Saigon, Vietnam

13 Days One-Way from Saigon to Siem Reap

RV Jahan

Departs
January 21st 2027
Duration
12 nights
From
$14,000
per person, double occupancy
Ports of call: +5 more ports

Cruise lines sailing the Mekong River

Often combined with