Mekong River Cruises

99 itineraries · 15 ships · 17 ports

Mekong River Cruises: 99 itineraries on 15 ships from 10 cruise lines, ranging from 7 to 27 nights. Ports along the Mekong River include Angkor Ban, Bến Tre, Cái Bè, Châu Đốc, Cho Gao and Cu Lao Gieng Island Vietnam.

Ports on the Mekong River

Mekong River Cruises: itineraries

Siem Reap, Cambodia

13 Days One-Way from Siem Reap to Saigon

Emerald Harmony

Departs
November 4th 2026
Duration
12 nights
From
$4,545
per person, double occupancy
Ports of call: +5 more ports
Hanoi, Vietnam

24 Days One-Way from Hanoi to Laem Chabang

Emerald Harmony

Departs
November 4th 2026
Duration
23 nights
From
$8,735
per person, double occupancy
Ports of call: +9 more ports
Hanoi, Vietnam

21 Days One-Way from Hanoi to Siem Reap

Emerald Harmony

Departs
November 4th 2026
Duration
20 nights
From
$6,645
per person, double occupancy
Ports of call: +7 more ports
Siem Reap, Cambodia

11 Days One-Way from Siem Reap to Saigon

Emerald Harmony

Departs
November 4th 2026
Duration
10 nights
From
$4,845
per person, double occupancy
Ports of call: +5 more ports
Hanoi, Vietnam

17 Days One-Way from Hanoi to Siem Reap

RV Indochine

Departs
November 4th 2026
Duration
16 nights
From
$5,133
per person, double occupancy
Ports of call: +5 more ports
Hanoi, Vietnam

23 Days One-Way from Hanoi to Saigon

Scenic Spirit

Departs
November 4th 2026
Duration
22 nights
Ports of call: +7 more ports
Phnom Penh, Cambodia

8 Days One-Way from Phnom Penh to Saigon

Avalon Saigon

Departs
November 5th 2026
Duration
7 nights
Ports of call: +1 more port
Siem Reap, Cambodia

17 Days One-Way from Siem Reap to Halong Bay

RV Indochine II

Departs
November 5th 2026
Duration
16 nights
From
$5,561
per person, double occupancy
Ports of call: +5 more ports
Siem Reap, Cambodia

14 Days One-Way from Siem Reap to Hanoi

RV Indochine II

Departs
November 5th 2026
Duration
13 nights
From
$4,859
per person, double occupancy
Ports of call: +3 more ports
Siem Reap, Cambodia

11 Days One-Way from Siem Reap to Saigon

RV Indochine II

Departs
November 5th 2026
Duration
10 nights
From
$3,368
per person, double occupancy
Ports of call: +1 more port
Hanoi, Vietnam

19 Days One-Way from Hanoi to Laem Chabang

Avalon Saigon

Departs
November 6th 2026
Duration
18 nights
From
$7,924
per person, double occupancy
Ports of call: +5 more ports
Hanoi, Vietnam

16 Days One-Way from Hanoi to Siem Reap

Avalon Saigon

Departs
November 6th 2026
Duration
15 nights
From
$6,784
per person, double occupancy
Ports of call: +4 more ports

Cruise lines sailing the Mekong River

Often combined with