Mekong River Cruises

99 itineraries · 15 ships · 17 ports

Mekong River Cruises: 99 itineraries on 15 ships from 10 cruise lines, ranging from 7 to 27 nights. Ports along the Mekong River include Angkor Ban, Bến Tre, Cái Bè, Châu Đốc, Cho Gao and Cu Lao Gieng Island Vietnam.

Ports on the Mekong River

Mekong River Cruises: itineraries

Siem Reap, Cambodia

9 Days One-Way from Siem Reap to Saigon

RV Indochine

Departs
November 18th 2026
Duration
8 nights
From
$1,981
per person, double occupancy
Ports of call:
Hanoi, Vietnam

23 Days One-Way from Hanoi to Saigon

Emerald Harmony

Departs
November 22nd 2026
Duration
22 nights
From
$6,295
per person, double occupancy
Ports of call: +9 more ports
Hanoi, Vietnam

17 Days One-Way from Hanoi to Siem Reap

Emerald Harmony

Departs
November 22nd 2026
Duration
16 nights
From
$5,945
per person, double occupancy
Ports of call: +5 more ports
Saigon, Vietnam

15 Days Saigon, Vietnam Round Trip

RV La Marguerite

Departs
November 23rd 2026
Duration
14 nights
From
$4,099
per person, double occupancy
Ports of call: +1 more port
Hanoi, Vietnam

18 Days One-Way from Hanoi to Saigon

Scenic Spirit

Departs
November 23rd 2026
Duration
17 nights
Ports of call: +5 more ports
Hanoi, Vietnam

21 Days One-Way from Hanoi to Saigon

Emerald Harmony

Departs
November 24th 2026
Duration
20 nights
From
$6,145
per person, double occupancy
Ports of call: +9 more ports
Saigon, Vietnam

8 Days One-Way from Saigon to Phnom Penh

Avalon Saigon

Departs
November 26th 2026
Duration
7 nights
Ports of call: +1 more port
Siem Reap, Cambodia

14 Days One-Way from Siem Reap to Hanoi

RV Indochine

Departs
December 2nd 2026
Duration
13 nights
From
$4,431
per person, double occupancy
Ports of call: +3 more ports
Siem Reap, Cambodia

11 Days One-Way from Siem Reap to Saigon

RV Indochine

Departs
December 2nd 2026
Duration
10 nights
From
$2,940
per person, double occupancy
Ports of call: +1 more port
Hanoi, Vietnam

24 Days One-Way from Hanoi to Saigon

Scenic Spirit

Departs
December 5th 2026
Duration
23 nights
Ports of call: +7 more ports
Saigon, Vietnam

15 Days One-Way from Saigon to Siem Reap

Scenic Spirit

Departs
December 6th 2026
Duration
14 nights
Ports of call: +4 more ports
Siem Reap, Cambodia

13 Days One-Way from Siem Reap to Saigon

Scenic Spirit

Departs
December 14th 2026
Duration
12 nights
Ports of call: +3 more ports

Cruise lines sailing the Mekong River

Often combined with