Mississippi River Cruises

52 itineraries · 6 ships · 20 ports

Mississippi River Cruises: 52 itineraries on 6 ships from 2 cruise lines, ranging from 7 to 22 nights. Ports along the Mississippi River include Alton, Baton Rouge, Burlington, Cape Girardeau, Darrow and Davenport.

Ports on the Mississippi River

Mississippi River Cruises: itineraries

Minneapolis-Saint Paul, United States

9 Days One-Way from Minneapolis-Saint Paul to St Louis Mo

ACL American Melody

Departs
June 25th 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call: +1 more port
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St Louis MO, United States

16 Days One-Way from St Louis Mo to Pittsburgh Pa

ACL American Melody

Departs
July 2nd 2027
Duration
15 nights
From
$9,240
per person, double occupancy
Ports of call: +4 more ports
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Minneapolis-Saint Paul, United States

9 Days One-Way from Minneapolis-Saint Paul to St Louis Mo

ACL American Serenade

Departs
July 2nd 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call: +1 more port
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New Orleans, United States

14 Days One-Way from New Orleans to Louisville Ky

ACL American Symphony

Departs
July 6th 2027
Duration
13 nights
From
$8,725
per person, double occupancy
Ports of call: +2 more ports
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New Orleans, United States

22 Days One-Way from New Orleans to Minneapolis-Saint Paul

Viking Mississippi

Departs
July 6th 2027
Duration
21 nights
From
$15,998
per person, double occupancy
Ports of call: +12 more ports
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New Orleans, United States

15 Days One-Way from New Orleans to Alton Il

Viking Mississippi

Departs
July 6th 2027
Duration
14 nights
From
$9,499
per person, double occupancy
Ports of call: +5 more ports
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St Louis MO, United States

9 Days One-Way from St Louis Mo to Minneapolis-Saint Paul

ACL American Serenade

Departs
July 9th 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call: +1 more port
View Voyage & Fares Request a Quote
New Orleans, United States

16 Days One-Way from New Orleans to Nashville Tn

American Splendor

Departs
July 13th 2027
Duration
15 nights
From
$8,075
per person, double occupancy
Ports of call: +4 more ports
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Alton IL, United States

8 Days One-Way from Alton Il to Minneapolis-Saint Paul

Viking Mississippi

Departs
July 20th 2027
Duration
7 nights
From
$6,499
per person, double occupancy
Ports of call: +2 more ports
View Voyage & Fares Request a Quote
Minneapolis-Saint Paul, United States

15 Days One-Way from Minneapolis-Saint Paul to New Orleans

Viking Mississippi

Departs
July 27th 2027
Duration
14 nights
From
$12,999
per person, double occupancy
Ports of call: +8 more ports
View Voyage & Fares Request a Quote
St Louis MO, United States

9 Days One-Way from St Louis Mo to Minneapolis-Saint Paul

ACL American Melody

Departs
July 30th 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call: +1 more port
View Voyage & Fares Request a Quote
Minneapolis-Saint Paul, United States

8 Days One-Way from Minneapolis-Saint Paul to Alton Il

Viking Mississippi

Departs
August 31st 2027
Duration
7 nights
From
$6,499
per person, double occupancy
Ports of call: +2 more ports
View Voyage & Fares Request a Quote

Cruise lines sailing the Mississippi River

Often combined with