Mississippi River Cruises

52 itineraries · 6 ships · 20 ports

Mississippi River Cruises: 52 itineraries on 6 ships from 2 cruise lines, ranging from 7 to 22 nights. Ports along the Mississippi River include Alton, Baton Rouge, Burlington, Cape Girardeau, Darrow and Davenport.

Ports on the Mississippi River

Mississippi River Cruises: itineraries

New Orleans, United States

8 Days New Orleans, USA Round Trip

American Heritage

Departs
November 1st 2026
Duration
7 nights
From
$3,630
per person, double occupancy
Ports of call:
Nashville TN, United States

8 Days One-Way from Nashville Tn to Memphis Tn

Viking Mississippi

Departs
November 3rd 2026
Duration
7 nights
From
$4,799
per person, double occupancy
Ports of call:
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

ACL American Melody

Departs
November 6th 2026
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
New Orleans, United States

8 Days One-Way from New Orleans to Pensacola Fl

ACL American Symphony

Departs
November 10th 2026
Duration
7 nights
From
$4,565
per person, double occupancy
Ports of call:
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

American Splendor

Departs
November 10th 2026
Duration
8 nights
From
$4,295
per person, double occupancy
Ports of call: +1 more port
Memphis TN, United States

8 Days One-Way from Memphis Tn to Nashville Tn

Viking Mississippi

Departs
November 10th 2026
Duration
7 nights
From
$5,299
per person, double occupancy
Ports of call:
New Orleans, United States

9 Days One-Way from New Orleans to Memphis Tn

ACL American Melody

Departs
November 13th 2026
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
Pensacola FL, United States

8 Days One-Way from Pensacola Fl to New Orleans

ACL American Symphony

Departs
November 16th 2026
Duration
7 nights
From
$4,565
per person, double occupancy
Ports of call:
Memphis TN, United States

8 Days One-Way from Memphis Tn to New Orleans

Viking Mississippi

Departs
November 24th 2026
Duration
7 nights
From
$4,299
per person, double occupancy
Ports of call: +2 more ports
New Orleans, United States

8 Days One-Way from New Orleans to Memphis Tn

Viking Mississippi

Departs
December 1st 2026
Duration
7 nights
From
$4,199
per person, double occupancy
Ports of call: +1 more port
New Orleans, United States

8 Days New Orleans, USA Round Trip

ACL American Melody

Departs
December 11th 2026
Duration
7 nights
From
$4,255
per person, double occupancy
Ports of call:
New Orleans, United States

8 Days New Orleans, USA Round Trip

Viking Mississippi

Departs
December 15th 2026
Duration
7 nights
From
$3,799
per person, double occupancy
Ports of call:

Cruise lines sailing the Mississippi River

Often combined with