Mississippi River Cruises

52 itineraries · 6 ships · 20 ports

Mississippi River Cruises: 52 itineraries on 6 ships from 2 cruise lines, ranging from 7 to 22 nights. Ports along the Mississippi River include Alton, Baton Rouge, Burlington, Cape Girardeau, Darrow and Davenport.

Ports on the Mississippi River

Mississippi River Cruises: itineraries

St Louis MO, United States

9 Days One-Way from St Louis Mo to Minneapolis-Saint Paul

ACL American Symphony

Departs
September 10th 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call: +1 more port
Minneapolis-Saint Paul, United States

16 Days One-Way from Minneapolis-Saint Paul to New Orleans

ACL American Symphony

Departs
September 17th 2027
Duration
15 nights
From
$12,620
per person, double occupancy
Ports of call: +6 more ports
Nashville TN, United States

16 Days One-Way from Nashville Tn to New Orleans

American Splendor

Departs
September 21st 2027
Duration
15 nights
From
$8,670
per person, double occupancy
Ports of call: +4 more ports
Minneapolis-Saint Paul, United States

16 Days One-Way from Minneapolis-Saint Paul to New Orleans

ACL American Serenade

Departs
September 24th 2027
Duration
15 nights
From
$12,620
per person, double occupancy
Ports of call: +6 more ports
New Orleans, United States

12 Days One-Way from New Orleans to Memphis Tn

ACL American Serenade

Departs
October 8th 2027
Duration
11 nights
From
$7,770
per person, double occupancy
Ports of call: +2 more ports
Minneapolis-Saint Paul, United States

16 Days One-Way from Minneapolis-Saint Paul to New Orleans

ACL American Melody

Departs
October 15th 2027
Duration
15 nights
From
$12,620
per person, double occupancy
Ports of call: +6 more ports
Memphis TN, United States

12 Days One-Way from Memphis Tn to New Orleans

ACL American Serenade

Departs
October 18th 2027
Duration
11 nights
From
$7,770
per person, double occupancy
Ports of call: +2 more ports
Nashville TN, United States

9 Days One-Way from Nashville Tn to Memphis Tn

ACL American Symphony

Departs
October 29th 2027
Duration
8 nights
From
$5,635
per person, double occupancy
Ports of call:
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

ACL American Symphony

Departs
December 3rd 2027
Duration
8 nights
From
$5,275
per person, double occupancy
Ports of call: +1 more port
New Orleans, United States

16 Days One-Way from New Orleans to Nashville Tn

ACL American Symphony

Departs
April 9th 2028
Duration
15 nights
From
$11,270
per person, double occupancy
Ports of call: +4 more ports
New Orleans, United States

9 Days One-Way from New Orleans to Memphis Tn

American Heritage

Departs
May 30th 2028
Duration
8 nights
From
$4,925
per person, double occupancy
Ports of call: +1 more port
Memphis TN, United States

9 Days One-Way from Memphis Tn to New Orleans

American Heritage

Departs
June 6th 2028
Duration
8 nights
From
$4,610
per person, double occupancy
Ports of call: +1 more port

Cruise lines sailing the Mississippi River

Often combined with