Cruises to South America

109 ships from 30 cruise lines across 9 countries

109
Cruise ships
30
Cruise lines
87
Places ships visit
9
Countries

Ships by type: 90 ocean 4 river 22 expedition · a ship that visits several places here is counted once; an expedition ship that also sails as an ocean ship appears under both types.

South America Cruises

Sailings that call at South America, earliest departure first.

827 Sailings Found
Cartagena Colombia, Colombia

8 Days One-Way from Cartagena Colombia to Barranquilla Colombia

AmaMelodia

Departs
November 18th 2026
Duration
7 nights
From
$4,484
per person, double occupancy
Ports of call:
Ushuaia, Argentina

11 Days Ushuaia, Argentina Round Trip

L'Austral

Departs
November 18th 2026
Duration
10 nights
From
$16,100
per person, double occupancy
Ports of call:
Fort Lauderdale, United States

17 Days One-Way from Fort Lauderdale to San Antonio

ms Oosterdam

Departs
November 18th 2026
Duration
16 nights
From
$2,359
per person, double occupancy
Ports of call: +4 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Fort Lauderdale, United States

31 Days One-Way from Fort Lauderdale to Buenos Aires

ms Oosterdam

Departs
November 18th 2026
Duration
30 nights
From
$4,989
per person, double occupancy
Ports of call: +13 more ports
Ushuaia, Argentina

10 Days One-Way from Ushuaia to Puerto Natales

National Geographic Explorer

Departs
November 18th 2026
Duration
9 nights
From
$12,912
per person, double occupancy
Ports of call:
Miami, United States

12 Days Miami, USA Round Trip

Norwegian Sun

Departs
November 18th 2026
Duration
11 nights
From
$1,519
per person, double occupancy
Ports of call: +2 more ports
Barcelona, Spain

17 Days One-Way from Barcelona to Buenos Aires

Celebrity Equinox

Departs
November 19th 2026
Duration
16 nights
From
$1,419
per person, double occupancy
Ports of call:
Fort Lauderdale, United States

18 Days One-Way from Fort Lauderdale to Buenos Aires

Majestic Princess

Departs
November 19th 2026
Duration
17 nights
From
$2,627
per person, double occupancy
Ports of call: +2 more ports
Fort Lauderdale, United States

34 Days One-Way from Fort Lauderdale to San Antonio

Majestic Princess

Departs
November 19th 2026
Duration
33 nights
From
$4,474
per person, double occupancy
Ports of call: +9 more ports
Funchal, Portugal

13 Days One-Way from Funchal to Rio De Janeiro

MSC Virtuosa

Departs
November 19th 2026
Duration
12 nights
From
$1,593
per person, double occupancy
Ports of call:
Funchal, Portugal

14 Days One-Way from Funchal to Santos

MSC Virtuosa

Departs
November 19th 2026
Duration
13 nights
From
$1,643
per person, double occupancy
Ports of call:
Ushuaia, Argentina

8 Days One-Way from Ushuaia to King George Island Antarctica

National Geographic Explorer

Departs
November 19th 2026
Duration
7 nights
From
$12,912
per person, double occupancy
Ports of call:
Puerto Natales, Chile

9 Days Puerto Natales, Chile Round Trip

National Geographic Orion

Departs
November 19th 2026
Duration
8 nights
From
$13,808
per person, double occupancy
Ports of call:
Ushuaia, Argentina

21 Days Ushuaia, Argentina Round Trip

Seabourn Venture

Departs
November 19th 2026
Duration
20 nights
From
$23,209
per person, double occupancy
Ports of call:
Santos, Brazil

4 Days Santos, Brazil Round Trip

MSC Musica

Departs
November 20th 2026
Duration
3 nights
From
$359
per person, double occupancy
Ports of call:
Quito, Ecuador

16 Days One-Way from Quito to Callao-Lima

National Geographic Delfina

Departs
November 20th 2026
Duration
15 nights
Ports of call: +8 more ports
Guayaquil, Ecuador

10 Days Guayaquil, Ecuador Round Trip

National Geographic Delfina

Departs
November 20th 2026
Duration
9 nights
Ports of call: +5 more ports
Cartagena Colombia, Colombia

8 Days One-Way from Cartagena Colombia to Barranquilla Colombia

AmaMagdalena

Departs
November 21st 2026
Duration
7 nights
From
$4,684
per person, double occupancy
Ports of call: