Panama Cruise Comparison
348 upcoming sailings from 24 cruise lines
Panama cruise port photos
Created by the Waterways Cruise content team and reviewed and fact-checked by J. Richard, Sr. Cruise Travel Agent and Founder of Waterways Cruise. Published · Last updated · About this page
At a glance: Panama cruises on Waterways Cruise: 348 upcoming sailings from 24 cruise lines (24 ocean). Lowest starting fares run from $566 per person (Royal Caribbean) to $20,890 (Scenic Cruises). Holland America lists the most sailings (32). 64 sailings start and 65 end in Panama.
Which cruise lines sail to Panama, and how do they compare? This guide sorts the 24 lines with upcoming Panama sailings by kind of cruise, then into ultra-luxury, luxury, premium and contemporary, and shows what each costs to start, how long their sailings run and which ships you would sail on. Every figure comes from the sailings we list today, so it moves as sailings are added and sold.
What counts as a Panama cruise?
A sailing counts as a Panama cruise if it will call at least once at a Panama ship port. That covers ocean and expedition sailings, whether Panama is where the cruise begins, where it ends, or one stop on a longer route.
Of 348 upcoming sailings, 64 start in Panama, 65 end in Panama and 10 begin and end there. The other 229 (66%) visit Panama as a port of call on a longer route, often alongside United States, Costa Rica, Colombia and other countries. Ocean and expedition sailings call at Panama Canal, Balboa, Colón, San Blas Islands Panama and Pearl Islands Panama.
- Panama cruise
- A sailing that will call at least once at a Panama ship port.
- Starts in Panama
- The first stop is a Panama ship port: 64 sailings.
- Ends in Panama
- The last stop is a Panama ship port: 65 sailings, 10 of which also start there.
- Visits only
- Panama is a port of call on a longer route: 229 sailings.
Ocean cruise lines in Panama (24)
24 ocean and expedition cruise lines have upcoming sailings that call at Panama: 348 in all. These sailings often call elsewhere too, most commonly United States, Costa Rica and Colombia. The busiest ship ports are Panama Canal, Balboa, Colón, San Blas Islands Panama and Pearl Islands Panama.
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Ultra-luxury ocean cruise lines (4)
Ultra-luxury lines sit at the top of the market. Four ultra-luxury ocean lines sail to Panama, with 54 upcoming sailings between them. Seabourn Cruises has the most (23). Starting fares begin at $4,929 per person with Seabourn Cruises.
| Cruise line | Upcoming sailings | Lowest starting fare | Typical length | Ships |
|---|---|---|---|---|
| Seabourn Cruises | 23 | $4,929 | 19–120 nights (typically 81) | 2 · Seabourn Pursuit and Seabourn Quest |
| Regent Seven Seas Cruises | 21 | $20,698 | 12–27 nights (typically 16) | 5 · Seven Seas Grandeur, Seven Seas Mariner, Seven Seas Prestige, Seven Seas Splendor and Seven Seas Voyager |
| Silversea Cruises | 8 | $7,700 | 13–77 nights (typically 18) | 4 · Silver Dawn, Silver Nova, Silver Ray and Silver Shadow |
| Ritz-Carlton Yacht Collection | 2 | $7,300 | 7 nights | 1 · Ritz-Carlton Evrima |
Luxury ocean cruise lines (4)
Luxury lines sit just below ultra-luxury. Four luxury ocean lines sail to Panama, with 56 upcoming sailings between them. Oceania Cruises has the most (27). Starting fares begin at $2,999 per person with Oceania Cruises.
| Cruise line | Upcoming sailings | Lowest starting fare | Typical length | Ships |
|---|---|---|---|---|
| Oceania Cruises | 27 | $2,999 | 10–45 nights (typically 10) | 5 · Oceania Insignia, Oceania Marina, Oceania Sirena, Oceania Sonata and Oceania Vista |
| Ponant Cruises | 19 | $5,360 | 7–12 nights (typically 10) | 4 · L'Austral, Le Bellot, Le Bougainville and Le Laperouse |
| MSC Explora Journeys | 5 | $7,280 | 9–21 nights (typically 9) | 1 · MSC Explora 3 |
| Scenic Cruises | 5 | $20,890 | 11–25 nights (typically 11) | 2 · Scenic Eclipse and Scenic Eclipse 2 |
Premium ocean cruise lines (7)
Premium lines sit in the middle of the market. Seven premium ocean lines sail to Panama, with 122 upcoming sailings between them. Windstar Cruises has the most (30). Starting fares begin at $2,416 per person with Windstar Cruises.
| Cruise line | Upcoming sailings | Lowest starting fare | Typical length | Ships |
|---|---|---|---|---|
| Windstar Cruises | 30 | $2,416 | 7–21 nights (typically 7) | 3 · Star Legend, Star Pride and Wind Star |
| Crystal Cruises | 22 | $4,540 | 10–41 nights (typically 10) | 2 · Crystal Serenity and Crystal Symphony |
| Viking Cruises | 22 | $3,599 | 10–68 nights (typically 17) | 5 · Viking Mars, Viking Octantis, Viking Polaris, Viking Sky and Viking Vesta |
| Azamara Cruises | 18 | $2,659 | 11–74 nights (typically 19) | 3 · Azamara Journey, Azamara Onward and Azamara Quest |
| Lindblad Expeditions | 11 | $6,125 | 4–7 nights (typically 7) | 1 · National Geographic Quest |
| Hapag-Lloyd Cruises | 11 | $9,208 | 14–24 nights (typically 14) | 3 · Hanseatic Inspiration, ms Europa and ms Europa 2 |
| Emerald Cruises | 8 | $10,296 | 7–18 nights (typically 18) | 1 · Emerald Azzurra |
Contemporary ocean cruise lines (8)
Contemporary lines are the most accessible tier. Eight contemporary ocean lines sail to Panama, with 105 upcoming sailings between them. Holland America has the most (32). Starting fares begin at $566 per person with Royal Caribbean.
| Cruise line | Upcoming sailings | Lowest starting fare | Typical length | Ships |
|---|---|---|---|---|
| Holland America | 32 | $1,319 | 14–28 nights (typically 21) | 6 · ms Eurodam, ms Nieuw Amsterdam, ms Oosterdam, ms Volendam, ms Zaandam and ms Zuiderdam |
| Princess Cruises | 22 | $934 | 16–23 nights (typically 16) | 7 · Caribbean Princess, Coral Princess, Crown Princess, Emerald Princess, Island Princess, Sapphire Princess and Star Princess |
| Cunard | 17 | $2,479 | 16–56 nights (typically 14) | 3 · Queen Anne, Queen Elizabeth and Queen Victoria |
| Norwegian Cruise Line | 15 | $1,439 | 11–20 nights (typically 15) | 6 · Norwegian Bliss, Norwegian Encore, Norwegian Gem, Norwegian Joy, Norwegian Star and Norwegian Sun |
| MSC Cruises | 8 | $946 | 18–29 nights (typically 11) | 2 · MSC Magnifica and MSC Poesia |
| Royal Caribbean | 7 | $566 | 7–10 nights (typically 7) | 2 · Grandeur Of The Seas and Serenade Of The Seas |
| Celebrity Cruises | 3 | $1,351 | 11–18 nights (typically 11) | 2 · Celebrity Ascent and Celebrity Summit |
| Virgin Voyages | 1 | $3,488 | 16 nights | 1 · Brilliant Lady |
Other ocean cruise lines (1)
These lines have not yet been placed in a style category. One other ocean line sails to Panama, with 11 upcoming sailings. Starting fares begin at $2,010 per person with Star Clippers.
| Cruise line | Upcoming sailings | Lowest starting fare | Typical length | Ships |
|---|---|---|---|---|
| Star Clippers | 11 | $2,010 | 7–14 nights (typically 7) | 2 · Royal Clipper and Star Clipper |
Panama cruise ports
Every Panama ship port with upcoming sailings has its own guide. The number beside each port is how many upcoming sailings call there (sailings, not individual port visits).
Coastal and island ports (10)
- Panama Canal 287
- Balboa 198
- Colón 113
- San Blas Islands Panama 60
- Pearl Islands Panama 25
- Isla Gamez Panama 24
- Bocas del Toro 18
- Coiba Island Panama 14
- Portobelo 14
- Gatun Lake Panama Canal 8
See them all in the Panama cruise port guide, or browse every sailing on the Panama cruises page.
How to choose a Panama cruise line
- Most listed sailings: Holland America lists the most upcoming Panama sailings (32).
- Lowest starting fare: Royal Caribbean, from $566 per person.
- Style: sort by category first. Star Clippers has no style category yet, so its 11 sailings are shown under Other and left out of the style totals. Ultra-luxury lines: 4 lines, 54 sailings, from $4,929. Luxury lines: 4 lines, 56 sailings, from $2,999. Premium lines: 7 lines, 122 sailings, from $2,416. Contemporary lines: 8 lines, 105 sailings, from $566. Other lines: 1 line, 11 sailings, from $2,010.
- Kind of cruise: Panama sailings here are ocean and expedition cruises.
- Where you start: if you want Panama as your first or last port, filter the sailings by Starting in or Ending in Panama on the Panama cruises page.
How we calculated these figures
- Upcoming sailing: an itinerary with at least one departure date from today onward, counted once however many departure dates it has. Sailings that have passed drop out each day.
- Panama cruise: a sailing that calls at least once at a Panama ship port. A sailing "starts" or "ends" in Panama when its first or last stop is a Panama ship port.
- Lowest starting fare: the lowest "from" price among that line's upcoming Panama sailings, per person based on double occupancy, in US dollars. Under our Cruise Disclosure, prices include all applicable taxes and fees. Fares still depend on cabin category and date, so treat them as a starting point for comparison, not a quote.
- Typical length: the range covers the middle 80% of that line's sailings (the shortest and longest tenth are left out), and "typically" is the most common length.
- Kinds of cruise: A sailing is in exactly one kind, so the totals by kind add up to the 348 sailings above. Ocean: sailings on ocean-going ships, including expedition ships and ferries. River: sailings on rivers, canals and lakes. A river itinerary that also includes a coastal leg counts as river. A line that sails more than one kind appears in each list, with its sailings split by kind. Totals by kind count each sailing once.
- Style categories: Ultra-luxury, Luxury, Premium and Contemporary are Waterways Cruise's own groupings of cruise lines, not an industry standard.
- Freshness: the sailing data is refreshed daily from the sailings we list; figures here were calculated on .
Frequently asked questions about Panama cruises
Which cruise lines sail to Panama?
24 cruise lines have upcoming Panama sailings on Waterways Cruise: 24 sail ocean or expedition itineraries. Holland America lists the most sailings (32).
How much does a Panama cruise cost?
Starting fares begin at $566 per person, double occupancy, with Royal Caribbean. Fares depend on the line, the cabin and the sailing date, so the best way to see current rates is to request exclusive rates for the dates you want.
Which cruise lines are ultra-luxury and luxury in Panama?
Ultra-luxury ocean lines: Seabourn Cruises, Regent Seven Seas Cruises, Silversea Cruises and Ritz-Carlton Yacht Collection. Luxury ocean lines: Oceania Cruises, Ponant Cruises, MSC Explora Journeys and Scenic Cruises.
Can you start or end a cruise in Panama?
Yes. 64 of 348 upcoming sailings start in Panama and 65 end there; 10 do both. The other 229 (66%) visit Panama as a port of call on a longer route.
Want help choosing?
Our advisors compare sailings, cabins and fares across all of these lines.
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Panama cruise port guide
Cruise ports, what to see, history and practical advice.
Panama cruise port guide →Created by the Waterways Cruise content team and reviewed and fact-checked by J. Richard, Sr. Cruise Travel Agent and Founder of Waterways Cruise.
Published September 9, 2026 · Last updated October 31, 2026
Fares, availability and itineraries change often. Confirm current details with your cruise line or a Waterways Cruise agent before you book.
Cruise Disclosure
Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.
We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!