São Tomé and Príncipe Cruises: Sailings, Embarkations & Ports of Call

6 ships from 4 cruise lines

São Tomé and Príncipe cruises at a glance

Waterways Cruise lists 11 upcoming sailings on 6 ships from 4 cruise lines visiting São Tomé and Príncipe, calling at 3 places. Cruises visit São Tomé and Príncipe as a port of call and do not start or end here. More Africa cruises.

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Compare São Tomé and Príncipe cruise lines

See every São Tomé and Príncipe cruise line by ocean and river and by ultra-luxury, luxury, premium and contemporary style, with fares, cruise lengths, ships and ports.

About São Tomé and Príncipe

São Tomé and Príncipe is Africa's second-smallest country, two volcanic islands in the Gulf of Guinea with a deeply layered Creole culture, world-class chocolate, empty beaches, and UNESCO-recognized rainforest. Cruise visitors can expect a raw, unhurried, non-touristy destination: no big resorts, no shopping streets, and no touts. The experience is best suited to travelers who find meaning in authentic encounters, natural history, and colonial plantation heritage.

Typical routes

  • West Africa Coastal Voyages: itineraries between Senegal, Ghana, Gabon, and Angola, often calling at São Tomé for one full day.
  • Atlantic Islands & Gulf of Guinea Expedition: smaller expedition vessels combine Cape Verde, São Tomé, Príncipe, and sometimes St. Helena, with more flexible landing schedules.

Ports overview

São Tomé and Príncipe has no dedicated cruise terminals. Commercial vessels use the main harbor in São Tomé, while Príncipe and smaller islets require tendering or zodiac landings. Cruise calls are irregular and often part of broader West Africa or Atlantic island expeditions.

Cruise season

Year-round tropical; drier and less humid from June to September (the 'gravana' season); calmer seas generally during the northern-hemisphere summer. Cruise calls are most reliable July–September, but some lines operate in December–April for world cruises.

Find your São Tomé and Príncipe sailing

Upcoming sailings calling at São Tomé and Príncipe, earliest departure first.

11 Sailings Found
Lisbon, Portugal

24 Days One-Way from Lisbon to Cape Town

Port call

Visits São Tomé and Príncipe. Also visits Portugal, Spain, Sao Vicente Island Cape Verde

Oceania Sirena

Departs
January 14th 2027
Duration
23 nights
From
$9,399
per person, double occupancy
Ports of call: +7 more ports
Cape Town, South Africa

25 Days One-Way from Cape Town to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Togo

Oceania Sirena

Departs
February 7th 2027
Duration
24 nights
From
$9,899
per person, double occupancy
Ports of call: +7 more ports
Lisbon, Portugal

25 Days One-Way from Lisbon to Cape Town

Port call

Visits São Tomé and Príncipe. Also visits Portugal, Spain, Sao Vicente Island Cape Verde

Seven Seas Navigator

Departs
February 12th 2027
Duration
24 nights
From
$40,098
per person, double occupancy
Ports of call: +7 more ports

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Dakar, Senegal

25 Days One-Way from Dakar to Cape Town

Port call

Visits São Tomé and Príncipe. Also visits Senegal, Ivory Coast, Ghana

Hanseatic Nature

Departs
October 29th 2027
Duration
24 nights
From
$34,356
per person, double occupancy
Ports of call: +4 more ports
Cape Town, South Africa

21 Days One-Way from Cape Town to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Togo

Seven Seas Navigator

Departs
November 20th 2027
Duration
20 nights
From
$28,798
per person, double occupancy
Ports of call: +4 more ports
Miami, United States

112 Days One-Way from Miami to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits United States, Panama, Ecuador

Seabourn Quest

Departs
January 7th 2028
Duration
112 nights
From
$72,799
per person, double occupancy
Ports of call: +36 more ports
Miami, United States

120 Days One-Way from Miami to Southampton

Port call

Visits São Tomé and Príncipe. Also visits United States, Panama, Ecuador

Seabourn Quest

Departs
January 7th 2028
Duration
120 nights
From
$77,999
per person, double occupancy
Ports of call: +42 more ports
Buenos Aires, Argentina

55 Days One-Way from Buenos Aires to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits Argentina, Saint Helena, United Kingdom

Seabourn Quest

Departs
March 5th 2028
Duration
54 nights
From
$31,449
per person, double occupancy
Ports of call: +18 more ports
Buenos Aires, Argentina

63 Days One-Way from Buenos Aires to Southampton

Port call

Visits São Tomé and Príncipe. Also visits Argentina, Saint Helena, United Kingdom

Seabourn Quest

Departs
March 5th 2028
Duration
62 nights
From
$35,954
per person, double occupancy
Ports of call: +24 more ports
Cape Town, South Africa

22 Days One-Way from Cape Town to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Angola

Seven Seas Mariner

Departs
April 28th 2028
Duration
21 nights
From
$37,398
per person, double occupancy
Ports of call: +4 more ports
Cape Town, South Africa

22 Days One-Way from Cape Town to Lisbon

Port call

Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Angola

Seven Seas Explorer

Departs
May 6th 2029
Duration
21 nights
From
$39,598
per person, double occupancy
Ports of call: +4 more ports

Where São Tomé and Príncipe cruises start and end

Embarkation ports (0)

No cruises start here.

Disembarkation ports (0)

No cruises end here.

6
Cruise ships
4
Cruise lines
3
Places ships visit
0
Embark / disembark places

Ships by type: 5 ocean 1 expedition · a ship that visits several places here is counted once; an expedition ship that also sails as an ocean ship appears under both types.

Plan your São Tomé and Príncipe cruise

São Tomé and Príncipe cruise port guide

Cruise ports, what to see, history and practical advice.

São Tomé and Príncipe cruise port guide →

Frequently asked questions about São Tomé and Príncipe cruises

How many places do cruises visit in São Tomé and Príncipe?

3 São Tomé and Príncipe places are visited by 6 ships from 4 cruise lines.

When is the best time to take a São Tomé and Príncipe cruise?

Year-round tropical; drier and less humid from June to September (the 'gravana' season); calmer seas generally during the northern-hemisphere summer. Cruise calls are most reliable July–September, but some lines operate in December–April for world cruises.

Sources and further reading

Background on São Tomé and Príncipe draws on these references. Sailing, fare and port data come from cruise line itineraries and are refreshed regularly.

Created by the Waterways Cruise content team and reviewed and fact-checked by , Sr. Cruise Travel Agent and Founder of Waterways Cruise.

Published September 9, 2026 · Last updated October 12, 2026

Fares, availability and itineraries change often. Confirm current details with your cruise line or a Waterways Cruise agent before you book.


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Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

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