São Tomé and Príncipe Cruises: Sailings, Embarkations & Ports of Call
6 ships from 4 cruise lines
São Tomé and Príncipe cruises at a glance
Waterways Cruise lists 11 upcoming sailings on 6 ships from 4 cruise lines visiting São Tomé and Príncipe, calling at 3 places. Cruises visit São Tomé and Príncipe as a port of call and do not start or end here. More Africa cruises.
Reviewed and fact-checked by J. Richard · About this page · About us
Compare São Tomé and Príncipe cruise lines
See every São Tomé and Príncipe cruise line by ocean and river and by ultra-luxury, luxury, premium and contemporary style, with fares, cruise lengths, ships and ports.
About São Tomé and Príncipe
São Tomé and Príncipe is Africa's second-smallest country, two volcanic islands in the Gulf of Guinea with a deeply layered Creole culture, world-class chocolate, empty beaches, and UNESCO-recognized rainforest. Cruise visitors can expect a raw, unhurried, non-touristy destination: no big resorts, no shopping streets, and no touts. The experience is best suited to travelers who find meaning in authentic encounters, natural history, and colonial plantation heritage.
Typical routes
- West Africa Coastal Voyages: itineraries between Senegal, Ghana, Gabon, and Angola, often calling at São Tomé for one full day.
- Atlantic Islands & Gulf of Guinea Expedition: smaller expedition vessels combine Cape Verde, São Tomé, Príncipe, and sometimes St. Helena, with more flexible landing schedules.
Ports overview
São Tomé and Príncipe has no dedicated cruise terminals. Commercial vessels use the main harbor in São Tomé, while Príncipe and smaller islets require tendering or zodiac landings. Cruise calls are irregular and often part of broader West Africa or Atlantic island expeditions.
Cruise season
Year-round tropical; drier and less humid from June to September (the 'gravana' season); calmer seas generally during the northern-hemisphere summer. Cruise calls are most reliable July–September, but some lines operate in December–April for world cruises.
Find your São Tomé and Príncipe sailing
Upcoming sailings calling at São Tomé and Príncipe, earliest departure first.
24 Days One-Way from Lisbon to Cape Town
Visits São Tomé and Príncipe. Also visits Portugal, Spain, Sao Vicente Island Cape Verde
Oceania Sirena
25 Days One-Way from Cape Town to Lisbon
Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Togo
Oceania Sirena
25 Days One-Way from Lisbon to Cape Town
Visits São Tomé and Príncipe. Also visits Portugal, Spain, Sao Vicente Island Cape Verde
Seven Seas Navigator
Why Book With Waterways Cruise?
Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.
Cruise Concierge
A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.
100% Custom‑Built
No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.
40+ Years in Travel
Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.
Book With Total Confidence
A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.
25 Days One-Way from Dakar to Cape Town
Visits São Tomé and Príncipe. Also visits Senegal, Ivory Coast, Ghana
Hanseatic Nature
21 Days One-Way from Cape Town to Lisbon
Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Togo
Seven Seas Navigator
112 Days One-Way from Miami to Lisbon
Visits São Tomé and Príncipe. Also visits United States, Panama, Ecuador
Seabourn Quest
120 Days One-Way from Miami to Southampton
Visits São Tomé and Príncipe. Also visits United States, Panama, Ecuador
Seabourn Quest
55 Days One-Way from Buenos Aires to Lisbon
Visits São Tomé and Príncipe. Also visits Argentina, Saint Helena, United Kingdom
Seabourn Quest
63 Days One-Way from Buenos Aires to Southampton
Visits São Tomé and Príncipe. Also visits Argentina, Saint Helena, United Kingdom
Seabourn Quest
22 Days One-Way from Cape Town to Lisbon
Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Angola
Seven Seas Mariner
22 Days One-Way from Cape Town to Lisbon
Visits São Tomé and Príncipe. Also visits South Africa, Namibia, Angola
Seven Seas Explorer
Where São Tomé and Príncipe cruises start and end
Embarkation ports (0)
No cruises start here.
Disembarkation ports (0)
No cruises end here.
Ships by type: 5 ocean 1 expedition · a ship that visits several places here is counted once; an expedition ship that also sails as an ocean ship appears under both types.
Plan your São Tomé and Príncipe cruise
São Tomé and Príncipe cruise port guide
Cruise ports, what to see, history and practical advice.
São Tomé and Príncipe cruise port guide →More Africa cruises
Morocco · Egypt · Tunisia · Algeria · Sao Vicente Island Cape Verde · South Africa · Namibia · Mauritius
Frequently asked questions about São Tomé and Príncipe cruises
How many places do cruises visit in São Tomé and Príncipe?
3 São Tomé and Príncipe places are visited by 6 ships from 4 cruise lines.
When is the best time to take a São Tomé and Príncipe cruise?
Year-round tropical; drier and less humid from June to September (the 'gravana' season); calmer seas generally during the northern-hemisphere summer. Cruise calls are most reliable July–September, but some lines operate in December–April for world cruises.
Sources and further reading
Background on São Tomé and Príncipe draws on these references. Sailing, fare and port data come from cruise line itineraries and are refreshed regularly.
- CIA World Factbook: São Tomé and Príncipe - The World Factbook
- Encyclopaedia Britannica: São Tomé and Príncipe
- UNESCO: Príncipe Island Biosphere Reserve
- Lonely Planet: São Tomé & Príncipe Travel Guide
- Wikimedia Commons: Category: São Tomé and Príncipe
Created by the Waterways Cruise content team and reviewed and fact-checked by J. Richard, Sr. Cruise Travel Agent and Founder of Waterways Cruise.
Published September 9, 2026 · Last updated October 12, 2026
Fares, availability and itineraries change often. Confirm current details with your cruise line or a Waterways Cruise agent before you book.
Cruise Disclosure
Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.
We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!





