Cruises from Colón

6 cruise lines and 12 ships sailing from Colón, Panama

Cruises visiting Colón

Colón puts you at Panama’s Caribbean gateway, where the Atlantic meets the Panama Canal. At Agua Clara Locks, watch ships pass through the expanded canal toward Gatun Lake. Nearby, Portobelo and San Lorenzo preserve Spanish colonial fortifications built to guard Caribbean trade routes. Colón is best approached as a gateway, with its strongest draws found in the canal, historic coast and surrounding rainforest.

Cruises from Colón, Panama

Sailings departing from Colón, earliest departure first.

26 Sailings Found
Colon, Panama

9 Days One-Way from Colon to Puntarenas

Wind Star

Departs
January 31st 2027
Duration
8 nights
From
$6,730
per person, double occupancy
Ports of call: +2 more ports
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Colon, Panama

30 Days One-Way from Colon to Papeete

Wind Star

Departs
January 31st 2027
Duration
29 nights
From
$9,946
per person, double occupancy
Ports of call: +3 more ports
View Voyage & Fares Request a Quote
Colon, Panama

36 Days One-Way from Colon to Papeete

Wind Star

Departs
January 31st 2027
Duration
35 nights
From
$15,182
per person, double occupancy
Ports of call: +8 more ports
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Colon, Panama

11 Days One-Way from Colon to Fort-De-France

Le Laperouse

Departs
March 12th 2027
Duration
10 nights
From
$7,820
per person, double occupancy
Ports of call: +3 more ports
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Colon, Panama

11 Days One-Way from Colon to Fort-De-France

Le Bellot

Departs
April 8th 2027
Duration
10 nights
From
$7,420
per person, double occupancy
Ports of call: +4 more ports
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Colon, Panama

8 Days One-Way from Colon to San Juan

Grandeur Of The Seas

Departs
April 24th 2027
Duration
7 nights
From
$566
per person, double occupancy
Ports of call:
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Colon, Panama

11 Days One-Way from Colon to Puntarenas

Le Bougainville

Departs
December 2nd 2027
Duration
10 nights
From
$8,160
per person, double occupancy
Ports of call:
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Colon, Panama

8 Days One-Way from Colon to Puntarenas

Star Pride

Departs
December 6th 2027
Duration
7 nights
From
$2,878
per person, double occupancy
Ports of call: +1 more port
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Colon, Panama

8 Days One-Way from Colon to Puntarenas

Le Bougainville

Departs
December 29th 2027
Duration
7 nights
From
$5,360
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
Colon, Panama

10 Days One-Way from Colon to Puntarenas

Star Clipper

Departs
January 20th 2028
Duration
9 nights
From
$3,240
per person, double occupancy
Ports of call: +3 more ports
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Colon, Panama

13 Days One-Way from Colon to Fort-De-France

Le Bougainville

Departs
March 4th 2028
Duration
12 nights
From
$8,170
per person, double occupancy
Ports of call: +6 more ports
View Voyage & Fares Request a Quote
Colon, Panama

13 Days One-Way from Colon to Fort-De-France

Le Bellot

Departs
April 11th 2028
Duration
12 nights
From
$7,680
per person, double occupancy
Ports of call: +6 more ports
View Voyage & Fares Request a Quote

Cruise lines embarking (starting) at Colón (6)

Cruise lineCategoryTypeShips departing from Colón
Ponant Cruises Luxury Ocean L'Austral (no upcoming dates — contact a Waterways Cruise consultant for additional dates on L'Austral cruises departing Colón), Le Bellot, Le Bougainville, Le Laperouse
Hapag-Lloyd Cruises Premium Ocean Hanseatic Inspiration, ms Europa
Lindblad Expeditions Premium Expedition National Geographic Quest
Windstar Cruises Premium Ocean Star Legend, Star Pride, Wind Star
Royal Caribbean Contemporary Ocean Grandeur Of The Seas
Star Clippers Ocean Star Clipper

The complete Waterways Cruise destination guide to Colón, Panama →

6
Cruise lines
12
Ships departing

Published August 18, 2026