Cruises from Louisville

2 cruise lines and 3 ships sailing from Louisville, United States

Cruises visiting Louisville

Louisville rewards a day ashore with a clear sense of place: riverfront views, historic neighborhoods, and Kentucky’s best-known traditions. Explore bourbon heritage at the Frazier History Museum or along the Urban Bourbon Trail. Baseball fans can watch bats take shape at the Louisville Slugger Museum & Factory. Churchill Downs, home of the Kentucky Derby, lies south of downtown. Save time for NuLu, where independent shops and restaurants make an inviting finale.

Cruises from Louisville, United States

Sailings departing from Louisville, earliest departure first.

4 Sailings Found
Louisville KY, United States

8 Days One-Way from Louisville Ky to Memphis Tn

Viking Mississippi

Departs
June 15th 2027
Duration
7 nights
From
$5,999
per person, double occupancy
Ports of call:
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Louisville KY, United States

15 Days One-Way from Louisville Ky to New Orleans

Viking Mississippi

Departs
June 15th 2027
Duration
14 nights
From
$11,498
per person, double occupancy
Ports of call: +6 more ports
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Louisville KY, United States

9 Days One-Way from Louisville Ky to Pittsburgh Pa

ACL American Symphony

Departs
July 18th 2027
Duration
8 nights
From
$5,815
per person, double occupancy
Ports of call:
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Louisville KY, United States

9 Days One-Way from Louisville Ky to Pittsburgh Pa

ACL American Melody

Departs
September 2nd 2028
Duration
8 nights
From
$6,215
per person, double occupancy
Ports of call:
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Cruise lines embarking (starting) at Louisville (2)

Cruise lineCategoryTypeShips departing from Louisville
American Cruise Lines Premium River ACL American Melody, ACL American Symphony
Viking River Cruises Premium River Viking Mississippi

The complete Waterways Cruise destination guide to Louisville, United States →

2
Cruise lines
3
Ships departing

Published September 11, 2026