Cruises from Palermo

2 cruise lines and 9 ships sailing from Palermo, Italy

Cruises visiting Palermo

Palermo rewards curious travellers with a vivid mix of Arab-Norman architecture, lively markets and Sicilian cooking. Start at the cathedral, where Norman, Gothic and Baroque details reflect the city’s layered past. Then walk through the Capo market or visit the Palatine Chapel, famed for its Byzantine mosaics. Leave time for pasta con le sarde or arancini; Palermo’s strongest impressions often arrive at the table.

Cruises from Palermo, Italy

Sailings departing from Palermo, earliest departure first.

14 Sailings Found
Palermo, Italy

7 Days Palermo, Italy Round Trip

MSC Seashore

Departs
April 14th 2028
Duration
6 nights
From
$969
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
Palermo, Italy

8 Days Palermo, Italy Round Trip

MSC Seashore

Departs
April 20th 2028
Duration
7 nights
From
$1,078
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote

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Cruise lines embarking (starting) at Palermo (2)

Cruise lineCategoryTypeShips departing from Palermo
Ponant Cruises Luxury Ocean Le Boreal, Le Ponant
MSC Cruises Contemporary Ocean MSC Euribia, MSC Meraviglia (no upcoming dates — contact a Waterways Cruise consultant for additional dates on MSC Meraviglia cruises departing Palermo), MSC Musica, MSC Seashore, MSC Seaview, MSC Splendida, MSC Virtuosa

The complete Waterways Cruise destination guide to Palermo, Italy →

2
Cruise lines
9
Ships departing

Published September 8, 2026