Cruises from Pittsburgh

1 cruise line and 3 ships sailing from Pittsburgh, United States

Cruises visiting Pittsburgh

At the meeting of the Allegheny and Monongahela rivers, Pittsburgh begins with a view worth pausing for. Ride the Duquesne Incline to Mount Washington, where the city’s bridges and three rivers spread below. The Andy Warhol Museum offers a distinctive collection. In Oakland, the Carnegie Museums of Art and Natural History deserve time. Then browse the Strip District’s food shops and market streets.

Cruises from Pittsburgh, United States

Sailings departing from Pittsburgh, earliest departure first.

4 Sailings Found
Pittsburgh PA, United States

16 Days One-Way from Pittsburgh Pa to St Louis Mo

ACL American Melody

Departs
July 16th 2027
Duration
15 nights
From
$9,240
per person, double occupancy
Ports of call: +3 more ports
View Voyage & Fares Request a Quote
Pittsburgh PA, United States

9 Days One-Way from Pittsburgh Pa to Louisville Ky

ACL American Symphony

Departs
July 26th 2027
Duration
8 nights
From
$5,815
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
Pittsburgh PA, United States

16 Days One-Way from Pittsburgh Pa to St Louis Mo

ACL American Symphony

Departs
August 27th 2027
Duration
15 nights
From
$9,240
per person, double occupancy
Ports of call: +3 more ports
View Voyage & Fares Request a Quote

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Pittsburgh PA, United States

9 Days One-Way from Pittsburgh Pa to Louisville Ky

ACL American Melody

Departs
August 26th 2028
Duration
8 nights
From
$5,815
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote

Cruise lines embarking (starting) at Pittsburgh (1)

Cruise lineCategoryTypeShips departing from Pittsburgh
American Cruise Lines Premium River ACL American Melody, ACL American Symphony, American Heritage (no upcoming dates — contact a Waterways Cruise consultant for additional dates on American Heritage cruises departing Pittsburgh)

The complete Waterways Cruise destination guide to Pittsburgh, United States →

1
Cruise lines
3
Ships departing

Published September 19, 2026