Cruises from San Diego

8 cruise lines and 14 ships sailing from San Diego, United States

Cruises visiting San Diego

San Diego makes an easy first impression: a working harbor, sunlit waterfront and Pacific air. From the cruise terminal, the USS Midway Museum and lively Embarcadero are close at hand. Balboa Park brings world-class museums, gardens and the San Diego Zoo together in one grand setting. In the Gaslamp Quarter, Victorian façades frame restaurants and bars. Nearby neighborhoods reveal Mexican heritage and coastal ease.

Cruises from San Diego, United States

Sailings departing from San Diego, earliest departure first.

56 Sailings Found
San Diego, United States

17 Days One-Way from San Diego to Miami

Norwegian Star

Departs
February 13th 2027
Duration
16 nights
From
$2,029
per person, double occupancy
Ports of call: +3 more ports
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San Diego, United States

36 Days San Diego, USA Round Trip

ms Koningsdam

Departs
February 13th 2027
Duration
35 nights
From
$4,524
per person, double occupancy
Ports of call: +5 more ports
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San Diego, United States

19 Days One-Way from San Diego to Vancouver

ms Koningsdam

Departs
March 20th 2027
Duration
18 nights
From
$2,059
per person, double occupancy
Ports of call: +1 more port
View Voyage & Fares Request a Quote

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San Diego, United States

12 Days One-Way from San Diego to Vancouver

ms Koningsdam

Departs
March 27th 2027
Duration
11 nights
From
$1,234
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

29 Days One-Way from San Diego to Vancouver

ms Koningsdam

Departs
March 27th 2027
Duration
28 nights
From
$3,304
per person, double occupancy
Ports of call: +5 more ports
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San Diego, United States

8 Days San Diego, USA Round Trip

ms Zaandam

Departs
March 28th 2027
Duration
7 nights
From
$894
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

5 Days One-Way from San Diego to Vancouver

ms Koningsdam

Departs
April 3rd 2027
Duration
4 nights
From
$489
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

14 Days San Diego, USA Round Trip

ms Zaandam

Departs
April 4th 2027
Duration
13 nights
From
$1,454
per person, double occupancy
Ports of call: +4 more ports
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San Diego, United States

7 Days One-Way from San Diego to Vancouver

ms Eurodam

Departs
April 17th 2027
Duration
6 nights
From
$749
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

8 Days One-Way from San Diego to Vancouver

ms Zaandam

Departs
April 17th 2027
Duration
7 nights
From
$944
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

5 Days One-Way from San Diego to Vancouver

ms Nieuw Amsterdam

Departs
April 28th 2027
Duration
4 nights
From
$509
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote
San Diego, United States

8 Days One-Way from San Diego to Vancouver

Serenade Of The Seas

Departs
May 2nd 2027
Duration
7 nights
From
$525
per person, double occupancy
Ports of call:
View Voyage & Fares Request a Quote

Cruise lines embarking (starting) at San Diego (8)

Cruise lineCategoryTypeShips departing from San Diego
Silversea Cruises Ultra Luxury Ocean Silver Whisper
Azamara Cruises Premium Ocean Azamara Quest
Crystal Cruises Premium Ocean Crystal Serenity, Crystal Symphony
Holland America Contemporary Ocean ms Eurodam, ms Koningsdam, ms Nieuw Amsterdam, ms Oosterdam, ms Zaandam, ms Zuiderdam
MSC Cruises Contemporary Ocean MSC Poesia (no upcoming dates — contact a Waterways Cruise consultant for additional dates on MSC Poesia cruises departing San Diego)
Norwegian Cruise Line Contemporary Ocean Norwegian Star
Princess Cruises Contemporary Ocean Island Princess
Royal Caribbean Contemporary Ocean Serenade Of The Seas

The complete Waterways Cruise destination guide to San Diego, United States →

8
Cruise lines
14
Ships departing

Published August 16, 2026