Greece Cruise from Piraeus to Barcelona — 11 Days

10 nights · Greece · Departs Piraeus-Athens (Greece) · Visiting Santorini Island, Valletta, Messina, Naples, Civitavecchia-Rome, Livorno, Villefranche-sur-Mer, Barcelona · Aboard MSC Explora Journeys on the MSC Explora 2

MSC Explora Journeys logo
Cruise lineMSC Explora Journeys
ShipMSC Explora 2
Duration10 nights
Port calls9
Departures1 sailings
From fare$4,830 per person
Year built2024
Guests1473
Cabins461
Crew640
Length248 m
Beam32 m
Cruising speed18.0 kn
  1. Day 1

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

  2. Day 2

    Santorini Island, Greece

    Few Greek islands make an entrance like Santorini, where whitewashed villages crown a volcanic caldera above the Aegean. Most cruise ships anchor offshore, and tenders land at the old port below Fira. Ride the cable car, or climb the steps, to reach the island’s capital and its celebrated views. Beyond Fira, Oia’s blue domes, the archaeological site of Akrotiri, and volcanic wines reward a longer day ashore.

  3. Day 4

    Valletta, Malta

    Valletta makes a powerful first impression, its honey-coloured walls rising above Grand Harbour. Founded by the Knights of St John in 1566, Malta’s compact capital rewards exploration on foot. Enter St John’s Co-Cathedral for Caravaggio’s monumental paintings, then follow Republic Street to cafés, palaces and the Upper Barrakka Gardens. From the terraces, watch ferries cross the harbour and look towards the Three Cities. Allow time for steep lanes and quiet side streets.

  4. Day 5

    Messina, Italy

    Messina faces Calabria across the narrow Strait of Messina, with mainland Italy visible from its waterfront. At noon, figures move across the cathedral’s clock tower, a daily spectacle best seen from the square. Nearby, Montorsoli’s 16th-century Fountain of Orion rewards a closer look. Excursions reach Taormina and Mount Etna, but Messina’s compact center also merits an unhurried walk.

  5. Day 6

    Naples, Italy

    Naples puts its history within reach: the port opens onto a compact city framed by Mount Vesuvius and the bay. UNESCO-listed streets lead to churches, palaces and the everyday theatre of southern Italian life. At the National Archaeological Museum, mosaics and objects from Pompeii and Herculaneum bring the Roman world sharply into focus. Stay close for Neapolitan pizza, or use Naples as a springboard to Pompeii, Herculaneum and Capri.

  6. Day 7

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  7. Day 8

    Livorno, Italy

    Livorno rewards those who look beyond the cruise terminal. Its canals, built in the style of Venice, wind through historic Venezia Nuova. The seafront promenade leads to Terrazza Mascagni, where black-and-white paving frames the sea. At Mercato Centrale, locals shop beneath a vast iron-and-glass roof. Try cacciucco, the city’s rich fish stew. Florence and Pisa are within reach, but Livorno merits time of its own.

  8. Day 9

    Villefranche-sur-Mer, France

    Villefranche-sur-Mer makes an unusually graceful first impression: pastel houses rise above one of the Riviera’s deepest natural harbors. Wander the old town’s narrow lanes, then visit the 16th-century citadel and its museums. Jean Cocteau’s painted Chapel of Saint-Pierre adds a distinctive local detail. Nearby trains connect you with Nice; roads lead to Èze and the wider Côte d’Azur.

  9. Day 11

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

MSC Explora 2 Cruises

Published August 4, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

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