Italy Cruise from Civitavecchia to Istanbul — 10 Days

9 nights · Italy · Departs Civitavecchia-Rome (Italy) · Visiting Salerno, Siracusa, Katakolon, Gythion, Mykonos Island, Patmos Island, Volos, Canakkale, Istanbul · Aboard Oceania Cruises on the Oceania Sirena

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Cruise lineOceania Cruises
ShipOceania Sirena
Duration9 nights
Port calls10
Departures3 sailings
From fare$2,699 per person
Year built1999
Guests803
Cabins349
Crew375
Length181 m
Beam25 m
Cruising speed20.0 kn
  1. Day 1

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  2. Day 2

    Salerno, Italy

    Salerno puts southern Italy within easy reach, with ferries and roads leading toward the Amalfi Coast. Yet the city rewards a closer look: its old lanes gather around the handsome Duomo di San Matteo. Inside, bronze doors and a richly decorated crypt recall Salerno’s medieval importance as a center of learning. Climb to Arechi Castle for broad views across the Gulf, or venture inland to the Greek temples at Paestum.

  3. Day 3

    Siracusa, Italy

    Siracusa rewards visitors who look beyond its handsome waterfront. On Ortigia, the old island heart, Greek temples, Baroque palaces and lively markets sit within an easy walk. Across the channel, Neapolis Archaeological Park preserves a Greek theatre, Roman amphitheatre and the famed Ear of Dionysius. Pause for granita or fresh seafood, then watch the light soften over the Ionian Sea.

  4. Day 4

    Katakolon, Greece

    Katakolon is a compact seaside port on the western Peloponnese, with cafés and shops lining its waterfront. Most visitors come for ancient Olympia, about 35 kilometres inland and readily reached by road. There, the sanctuary, archaeological museum and ancient stadium bring the story of the Olympic Games into focus. Back in Katakolon, allow time for a stroll along the harbour before returning to your ship.

  5. Day 5

    Gythion, Greece

    Gythion gives you a gentler gateway to the southern Peloponnese, where the Mani begins in stone and sea. Once Sparta’s seaport, this harbor town faces the water with neoclassical houses, fishing boats, and café-lined quays. Walk to Marathonisi, the islet linked by a causeway, or follow the coast to Mavrovouni’s long beach. From here, the Mani’s tower villages and the caves of Diros make rewarding excursions. Choose Gythion for an unhurried introduction to a rugged, less-traveled corner of Greece.

  6. Day 6

    Mykonos Island, Greece

    Mykonos rewards an early start: whitewashed lanes, blue-domed churches and waterfront cafés are quieter before the cruise crowds arrive. In Little Venice, old captains’ houses lean over the Aegean, while the island’s windmills stand above the harbor. Beyond town, beaches range from lively Psarou to the broad sands of Elia. Take a short boat ride to Delos, where ancient sanctuaries and marble streets mark one of Greece’s great archaeological sites.

  7. Day 7

    Patmos Island, Greece

    Patmos, a small Dodecanese island, pairs a quiet harbour with a remarkable religious history. From Skala, a winding road climbs to Chora, where whitewashed lanes lead to the Monastery of Saint John. Nearby, the Cave of the Apocalypse recalls the tradition that John received the visions behind Revelation. These UNESCO-listed sites reward a visit; beaches and waterfront tavernas offer a gentler counterpoint.

  8. Day 8

    Volos, Greece

    Volos sits at the head of the Pagasetic Gulf, with Mount Pelion rising behind the city. Its waterfront cafés and lively tsipouradika serve the local ritual of tsipouro with small plates. The Archaeological Museum displays finds from Thessaly, including rare Neolithic objects. Beyond town, Pelion villages offer stone mansions, shaded squares and mountain paths. Take the historic narrow-gauge railway through the hills, or follow the coast to clear-water beaches.

  9. Day 9

    Canakkale, Turkey

    Çanakkale stands on the Asian shore of the Dardanelles, where Europe and Asia face each other across a busy strait. Its waterfront cafés, ferry traffic and Ottoman-era Çimenlik Castle offer a direct introduction to the city’s maritime past. Across the water, Gallipoli’s battlefields and memorials recall the 1915 campaign, while ancient Troy lies about 30 kilometres south. Both make compelling excursions, but leave time to walk the promenade and watch ferries cross the strait.

  10. Day 10

    Istanbul, Turkey

    Istanbul makes a compelling first impression: minarets rise above the Bosphorus, while ferries cross between Europe and Asia. On the historic peninsula, Hagia Sophia, the Blue Mosque and Topkapi Palace place centuries of empire within walking distance. Istanbul rewards curiosity beyond its landmarks. Browse the Grand Bazaar, linger over Turkish coffee, then take a ferry to the Asian shore. Allow time for traffic and queues; the city’s scale is part of the experience.

Oceania Sirena Cruises

Published September 26, 2026
Last updated October 3, 2026
Author: J. Richard


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