Italy Cruise from Civitavecchia to Piraeus — 17 Days

16 nights · Italy · Departs Civitavecchia-Rome (Italy) · Visiting Naples, Messina, Valletta, Split, Koper, Venice, Rijeka, Igoumenitsa, Katakolon, Gythion, Kusadasi, Milos Island, Piraeus-Athens · Aboard Regent Seven Seas Cruises on the Seven Seas Grandeur

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Grandeur
Duration16 nights
Port calls14
Departures1 sailings
From fare$37,998 per person
Year built2023
Guests829
Cabins375
Crew542
Length223 m
Beam32 m
Cruising speed22.0 kn
  1. Day 1

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  2. Day 2

    Naples, Italy

    Naples puts its history within reach: the port opens onto a compact city framed by Mount Vesuvius and the bay. UNESCO-listed streets lead to churches, palaces and the everyday theatre of southern Italian life. At the National Archaeological Museum, mosaics and objects from Pompeii and Herculaneum bring the Roman world sharply into focus. Stay close for Neapolitan pizza, or use Naples as a springboard to Pompeii, Herculaneum and Capri.

  3. Day 3

    Messina, Italy

    Messina faces Calabria across the narrow Strait of Messina, with mainland Italy visible from its waterfront. At noon, figures move across the cathedral’s clock tower, a daily spectacle best seen from the square. Nearby, Montorsoli’s 16th-century Fountain of Orion rewards a closer look. Excursions reach Taormina and Mount Etna, but Messina’s compact center also merits an unhurried walk.

  4. Day 4

    Valletta, Malta

    Valletta makes a powerful first impression, its honey-coloured walls rising above Grand Harbour. Founded by the Knights of St John in 1566, Malta’s compact capital rewards exploration on foot. Enter St John’s Co-Cathedral for Caravaggio’s monumental paintings, then follow Republic Street to cafés, palaces and the Upper Barrakka Gardens. From the terraces, watch ferries cross the harbour and look towards the Three Cities. Allow time for steep lanes and quiet side streets.

  5. Day 6

    Split, Croatia

    Split is Croatia’s second-largest city, but its heart feels remarkably intimate. Inside Diocletian’s Palace, Roman walls frame cafés, shops and homes. The cathedral and Peristyle recall the emperor’s former residence. Walk the Riva for views across the harbor and its working waterfront. Then climb Marjan Hill for a broad panorama of red roofs and Adriatic islands. Few ports make history so easy to enter on foot.

  6. Day 7

    Koper, Slovenia

    Koper rewards travellers who step ashore ready to explore on foot. Slovenia’s principal seaport opens onto a compact old town shaped by centuries of Venetian rule. At Tito Square, the Praetorian Palace and the cathedral’s bell tower frame a handsome introduction to the city. Beyond its stone lanes, the Istrian hinterland offers vineyards, olive groves and Karst landscapes. Stay awhile: Koper’s quiet confidence is part of its appeal.

  7. Day 8

    Venice, Italy

    Arrive in Venice by water, where the lagoon’s canals replace ordinary streets. St Mark’s Basilica and Doge’s Palace anchor the celebrated Piazza San Marco. Take a vaporetto along the Grand Canal, then explore a quieter neighborhood on foot. Confirm your ship’s terminal and transfer arrangements before setting out; cruise access varies. Near Rialto, the market and bridge offer a lively glimpse of the city’s trade. Give yourself time to leave the main routes and follow smaller canals.

  8. Day 9

    Rijeka, Croatia

    Rijeka is Croatia’s working seaport, set at the head of the Kvarner Gulf beneath steep green hills. From the quays, Austro-Hungarian façades and lively Korzo make a compelling first encounter. Visit the Central Market for local produce, then head to hilltop Trsat Castle for views across the harbor and islands. Beyond the waterfront, Roman remains, grand civic buildings, and everyday cafés reveal a city shaped by many eras.

  9. Day 11

    Igoumenitsa, Greece

    Igoumenitsa is western Greece’s working gateway, where ferries link the mainland with Corfu and Italy. Beyond the port, Epirus rewards a longer look. Ancient Dodona, one of Greece’s oldest oracles, lies inland. Along the coast, Parga and Sivota offer waterfront lanes, sheltered coves and clear Ionian water. Use Igoumenitsa as more than a transit stop; its setting opens a quieter route into Greece’s mountainous northwest.

  10. Day 12

    Katakolon, Greece

    Katakolon is a compact seaside port on the western Peloponnese, with cafés and shops lining its waterfront. Most visitors come for ancient Olympia, about 35 kilometres inland and readily reached by road. There, the sanctuary, archaeological museum and ancient stadium bring the story of the Olympic Games into focus. Back in Katakolon, allow time for a stroll along the harbour before returning to your ship.

  11. Day 13

    Gythion, Greece

    Gythion gives you a gentler gateway to the southern Peloponnese, where the Mani begins in stone and sea. Once Sparta’s seaport, this harbor town faces the water with neoclassical houses, fishing boats, and café-lined quays. Walk to Marathonisi, the islet linked by a causeway, or follow the coast to Mavrovouni’s long beach. From here, the Mani’s tower villages and the caves of Diros make rewarding excursions. Choose Gythion for an unhurried introduction to a rugged, less-traveled corner of Greece.

  12. Day 15

    Kusadasi, Turkey

    Kuşadası puts the Aegean within reach, with a lively waterfront and one of Turkey’s most celebrated ancient cities nearby. Ephesus lies about 20 kilometres inland, where marble avenues lead to the Library of Celsus and Great Theatre. Back in town, browse the bazaar, then follow the causeway to Pigeon Island and its historic fortress. The harbour-facing promenade offers an easy place to linger over the Aegean light.

  13. Day 16

    Milos Island, Greece

    Arrive at Adamas, Milos’s sheltered ferry port, and you step onto an island shaped by fire and sea. Its volcanic geology has carved pale cliffs, sea caves, and beaches across the coast. Visit Sarakiniko’s sculpted white rock, then climb to Plaka for island-wide views and a quiet evening. At Tripiti, visit the early Christian catacombs and ancient theater, near where the Venus de Milo was found in 1820.

  14. Day 17

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

Seven Seas Grandeur Cruises

Published August 2, 2026
Last updated October 3, 2026
Author: J. Richard


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