Spain Cruise from Barcelona to Venice — 18 Days

17 nights · Spain · Departs Barcelona (Spain) · Visiting Palamos, Sete, Toulon, Cannes, Portofino, La Spezia, Porto Cervo, Civitavecchia-Rome, Naples, Messina, Valletta, Split, Koper, Venice · Aboard Regent Seven Seas Cruises on the Seven Seas Grandeur

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Grandeur
Duration17 nights
Port calls15
Departures1 sailings
From fare$40,798 per person
Year built2023
Guests829
Cabins375
Crew542
Length223 m
Beam32 m
Cruising speed22.0 kn
  1. Day 1

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

  2. Day 2

    Palamos, Spain

    Palamós brings you to the heart of Spain’s Costa Brava, where a working fishing port meets a handsome old town. Its waterfront is famed for the prawns landed here, best sampled at a local table. Walk the promenade, visit the Fishing Museum, or follow coastal paths towards rocky coves and clear water. Girona and medieval villages lie inland, but Palamós rewards a slower day close to the sea.

  3. Day 3

    Sete, France

    Sète is France’s working Mediterranean port, set between the sea and the vast Étang de Thau. Canals cross the centre, alongside fishing boats, cafés and a covered market. Ride or walk up Mont Saint-Clair for broad views across the harbour, lagoons and coast. Sample oysters from nearby Bouzigues or choose the day’s catch at a port-side restaurant. Museums honour poet Paul Valéry and singer Georges Brassens, both born here, adding cultural depth to this lively port.

  4. Day 4

    Toulon, France

    Toulon is a working Mediterranean port, framed by limestone hills and one of Europe’s finest natural harbours. Look beyond the waterfront to the old town, where Cours Lafayette’s market fills the street with Provençal produce. For a wider view, ride the cable car up Mont Faron, then visit its memorial to the 1944 Allied landings. Nearby, the Îles d’Hyères, local beaches and cafés offer an easy-paced taste of coastal Provence.

  5. Day 5

    Cannes, France

    Arrive in Cannes and the Riviera’s polished glamour is immediately on show. Follow the palm-lined Croisette past Belle Époque hotels, designer boutiques and the Palais des Festivals, home of the film festival. Then climb into Le Suquet, the old quarter, for narrow lanes and views across the harbour. At Marché Forville, local produce and Provençal specialities offer a taste of everyday life. Ferries to the Lérins Islands make an easy escape to pine-scented shores.

  6. Day 7

    Portofino, Italy

    Portofino is a small Ligurian harbour, framed by green hills and pastel façades. On its crescent waterfront, fishing boats share the view with polished yachts. From the piazzetta, lanes climb to Castello Brown, a former fortress overlooking the harbour and coast. Walk on to the lighthouse at Punta del Capo, or take a boat to nearby Santa Margherita Ligure. A table by the water offers the best reason to linger.

  7. Day 8

    La Spezia, Italy

    La Spezia sits at the head of the Gulf of Poets. Here, Liguria’s steep hills meet a sheltered stretch of Mediterranean coast. Its working harbor gives the city a lively maritime character, while cafés and broad streets reward an easy stroll. Trains connect La Spezia with the villages of the Cinque Terre; ferries sail to Portovenere. Allow time for the city itself, not just its celebrated neighbors.

  8. Day 9

    Porto Cervo, Italy

    Porto Cervo is the Costa Smeralda’s polished heart, where Sardinia’s granite coast meets the Mediterranean’s deep blue. Its marina fills with sailing boats and superyachts, while the Piazzetta gathers cafés, boutiques and evening promenades. Built from the 1960s onward under the vision of Prince Karim Aga Khan, the resort has a distinct architectural character. Visit the whitewashed Stella Maris church, then seek clear water and quieter coves along the coast.

  9. Day 11

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  10. Day 12

    Naples, Italy

    Naples puts its history within reach: the port opens onto a compact city framed by Mount Vesuvius and the bay. UNESCO-listed streets lead to churches, palaces and the everyday theatre of southern Italian life. At the National Archaeological Museum, mosaics and objects from Pompeii and Herculaneum bring the Roman world sharply into focus. Stay close for Neapolitan pizza, or use Naples as a springboard to Pompeii, Herculaneum and Capri.

  11. Day 13

    Messina, Italy

    Messina faces Calabria across the narrow Strait of Messina, with mainland Italy visible from its waterfront. At noon, figures move across the cathedral’s clock tower, a daily spectacle best seen from the square. Nearby, Montorsoli’s 16th-century Fountain of Orion rewards a closer look. Excursions reach Taormina and Mount Etna, but Messina’s compact center also merits an unhurried walk.

  12. Day 14

    Valletta, Malta

    Valletta makes a powerful first impression, its honey-coloured walls rising above Grand Harbour. Founded by the Knights of St John in 1566, Malta’s compact capital rewards exploration on foot. Enter St John’s Co-Cathedral for Caravaggio’s monumental paintings, then follow Republic Street to cafés, palaces and the Upper Barrakka Gardens. From the terraces, watch ferries cross the harbour and look towards the Three Cities. Allow time for steep lanes and quiet side streets.

  13. Day 16

    Split, Croatia

    Split is Croatia’s second-largest city, but its heart feels remarkably intimate. Inside Diocletian’s Palace, Roman walls frame cafés, shops and homes. The cathedral and Peristyle recall the emperor’s former residence. Walk the Riva for views across the harbor and its working waterfront. Then climb Marjan Hill for a broad panorama of red roofs and Adriatic islands. Few ports make history so easy to enter on foot.

  14. Day 17

    Koper, Slovenia

    Koper rewards travellers who step ashore ready to explore on foot. Slovenia’s principal seaport opens onto a compact old town shaped by centuries of Venetian rule. At Tito Square, the Praetorian Palace and the cathedral’s bell tower frame a handsome introduction to the city. Beyond its stone lanes, the Istrian hinterland offers vineyards, olive groves and Karst landscapes. Stay awhile: Koper’s quiet confidence is part of its appeal.

  15. Day 18

    Venice, Italy

    Arrive in Venice by water, where the lagoon’s canals replace ordinary streets. St Mark’s Basilica and Doge’s Palace anchor the celebrated Piazza San Marco. Take a vaporetto along the Grand Canal, then explore a quieter neighborhood on foot. Confirm your ship’s terminal and transfer arrangements before setting out; cruise access varies. Near Rialto, the market and bridge offer a lively glimpse of the city’s trade. Give yourself time to leave the main routes and follow smaller canals.

Seven Seas Grandeur Cruises

Published August 18, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

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