Greece Cruise from Piraeus to Istanbul — 10 Days

9 nights · Greece · Departs Piraeus-Athens (Greece) · Visiting Souda-Chania, Santorini Island, Mykonos Island, Bodrum, Kusadasi, Dikili, Bozcaada Island, Istanbul · Aboard Regent Seven Seas Cruises on the Seven Seas Mariner

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Mariner
Duration9 nights
Port calls9
Departures1 sailings
From fare$23,798 per person
Year built2001
Guests779
Cabins354
Crew445
Length216 m
Beam28 m
Cruising speed21.0 kn
  1. Day 1

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

  2. Day 2

    Souda-Chania, Greece

    Souda Bay places you within easy reach of Chania, one of Crete’s most compelling historic towns. A short drive leads to Chania’s Venetian harbour, with its lighthouse, waterfront cafés and narrow lanes. On the Akrotiri peninsula, monasteries and coastal views share the landscape with the Allied war cemetery overlooking Souda Bay. Make time for Cretan cooking, distinguished by fine olive oil, local cheeses and wild herbs.

  3. Day 3

    Santorini Island, Greece

    Few Greek islands make an entrance like Santorini, where whitewashed villages crown a volcanic caldera above the Aegean. Most cruise ships anchor offshore, and tenders land at the old port below Fira. Ride the cable car, or climb the steps, to reach the island’s capital and its celebrated views. Beyond Fira, Oia’s blue domes, the archaeological site of Akrotiri, and volcanic wines reward a longer day ashore.

  4. Day 4

    Mykonos Island, Greece

    Mykonos rewards an early start: whitewashed lanes, blue-domed churches and waterfront cafés are quieter before the cruise crowds arrive. In Little Venice, old captains’ houses lean over the Aegean, while the island’s windmills stand above the harbor. Beyond town, beaches range from lively Psarou to the broad sands of Elia. Take a short boat ride to Delos, where ancient sanctuaries and marble streets mark one of Greece’s great archaeological sites.

  5. Day 6

    Bodrum, Turkey

    Bodrum brings the Aegean within reach: a handsome harbor, whitewashed houses and the Crusader-built Castle of St Peter. Its Museum of Underwater Archaeology displays finds recovered from ancient shipwrecks. Explore ancient Halicarnassus, whose Mausoleum was one of the Seven Wonders of the Ancient World. Then settle at a waterfront table for grilled fish and a view across the bay.

  6. Day 7

    Kusadasi, Turkey

    Kuşadası puts the Aegean within reach, with a lively waterfront and one of Turkey’s most celebrated ancient cities nearby. Ephesus lies about 20 kilometres inland, where marble avenues lead to the Library of Celsus and Great Theatre. Back in town, browse the bazaar, then follow the causeway to Pigeon Island and its historic fortress. The harbour-facing promenade offers an easy place to linger over the Aegean light.

  7. Day 8

    Dikili, Turkey

    Dikili brings you to Turkey’s quieter Aegean shore, where pine-fringed hills meet clear water and a relaxed harbour town. Its greatest prize lies inland: Bergama, ancient Pergamon, about 30 kilometres away. Explore the Acropolis, the remains of a celebrated library, and the Asclepieion, once a major healing sanctuary. Back in Dikili, stroll the waterfront, swim at a nearby beach, or linger over fresh seafood before returning aboard.

  8. Day 9

    Bozcaada Island, Turkey

    Bozcaada lies in the northern Aegean, a short ferry ride from Geyikli on Turkey’s Çanakkale coast. Its harbor is watched by a castle, rebuilt under Ottoman rule and visible as ferries approach. Beyond the waterfront, lanes pass stone houses, cafés and churches that reflect the island’s Greek and Turkish past. Vineyards cover the inland slopes, while Ayazma Beach offers a swim in clear Aegean water.

  9. Day 10

    Istanbul, Turkey

    Istanbul makes a compelling first impression: minarets rise above the Bosphorus, while ferries cross between Europe and Asia. On the historic peninsula, Hagia Sophia, the Blue Mosque and Topkapi Palace place centuries of empire within walking distance. Istanbul rewards curiosity beyond its landmarks. Browse the Grand Bazaar, linger over Turkish coffee, then take a ferry to the Asian shore. Allow time for traffic and queues; the city’s scale is part of the experience.

Seven Seas Mariner Cruises

Published September 13, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

We work hard to make sure everything on this website is accurate and up to date. However, some information may be incomplete or inaccurate, including details supplied by third parties or otherwise outside our control, and we cannot be held responsible for such errors. We work with 41 cruise line operators, that are providing cruises on 585 ships visiting 1,731 ports across 7,194 unique cruises, creating 13,822 itineraries. This is a great deal of data to continually update daily from our suppliers. If a pricing error, misrepresentation, or omission occurs, we reserve the right to adjust the pricing, correct the information, or cancel or decline any booking made in error, with notice to you. Thank you for your understanding!