Cruises Visiting Portobelo

14 sailings calling at Portobelo, Panama

Cruises Visiting Portobelo

Every upcoming sailing that calls at Portobelo, earliest departure first.

14 Sailings Found
Panama City, Panama

8 Days One-Way from Panama City to Cartagena Colombia

National Geographic Quest

Departs
October 31st 2026
Duration
7 nights
From
$7,449
per person, double occupancy
Ports of call: +1 more port
Colon, Panama

8 Days One-Way from Colon to Panama City

National Geographic Quest

Departs
December 6th 2026
Duration
7 nights
From
$6,150
per person, double occupancy
Ports of call:
Fort-de-France, Martinique

13 Days One-Way from Fort-De-France to Colon

Le Laperouse

Departs
December 7th 2026
Duration
12 nights
From
$8,800
per person, double occupancy
Ports of call: +4 more ports

Why Book With Waterways Cruise?

Four decades of expertise, one dedicated advisor, and every detail handled, from your front door to the gangway and back.

Personal Service

Cruise Concierge

A dedicated advisor who learns your name, your travel style and your preferences, then stays with you from the first conversation to the day you return home. Not a call center. Never a stranger.

Tailor-Made

100% Custom‑Built

No cookie-cutter packages. Flights, hotels, transfers and shore days are designed from scratch around how you actually like to travel, then refined until the trip feels like yours.

Expertise

40+ Years in Travel

Founded by J. Richard, a four-decade veteran of the travel industry, and focused solely on premium river and ocean cruising. Decades of ship and itinerary knowledge go into every recommendation.

Security

Book With Total Confidence

A travel agency that is a proud member of Signature Travel Network, CLIA, ASTA and IATA.

Panama City, Panama

8 Days One-Way from Panama City to Colon

National Geographic Quest

Departs
December 13th 2026
Duration
7 nights
From
$6,150
per person, double occupancy
Ports of call:
land tour, train/bus travel

9 Days One-Way from Land Tour to Panama City

National Geographic Quest

Departs
January 13th 2027
Duration
8 nights
From
$6,125
per person, double occupancy
Ports of call:
Colon, Panama

8 Days One-Way from Colon to Puntarenas

Le Laperouse

Departs
January 15th 2027
Duration
7 nights
From
$6,230
per person, double occupancy
Ports of call:
Panama City, Panama

12 Days One-Way from Panama City to Oranjestad Aruba

Star Clipper

Departs
January 16th 2027
Duration
11 nights
From
$3,150
per person, double occupancy
Ports of call: +3 more ports
Colon, Panama

5 Days One-Way from Colon to Panama City

National Geographic Quest

Departs
January 17th 2027
Duration
4 nights
From
$6,125
per person, double occupancy
Ports of call:
Panama City, Panama

5 Days One-Way from Panama City to Colon

National Geographic Quest

Departs
January 21st 2027
Duration
4 nights
From
$6,125
per person, double occupancy
Ports of call:
Panama City, Panama

8 Days Panama City, Panama Round Trip

National Geographic Quest

Departs
January 29th 2027
Duration
7 nights
From
$8,000
per person, double occupancy
Ports of call:
Fort-de-France, Martinique

13 Days One-Way from Fort-De-France to Colon

Le Bougainville

Departs
November 20th 2027
Duration
12 nights
Ports of call: +6 more ports
Panama City, Panama

12 Days One-Way from Panama City to Oranjestad Aruba

Star Clipper

Departs
February 21st 2028
Duration
12 nights
From
$4,190
per person, double occupancy
Ports of call: +2 more ports
Colon, Panama

13 Days One-Way from Colon to Fort-De-France

Le Bougainville

Departs
March 4th 2028
Duration
12 nights
From
$8,170
per person, double occupancy
Ports of call: +6 more ports
Departs
April 11th 2028
Duration
12 nights
From
$7,680
per person, double occupancy
Ports of call: +6 more ports