| Cruise line | Azamara Cruises |
|---|---|
| Ship | Azamara Quest |
| Duration | 18 nights |
| Port calls | 9 |
| Departures | 1 sailings |
| From fare | $3,999 per person |
| Year built | 2000 |
| Guests | 794 |
| Cabins | 361 |
| Crew | 408 |
| Length | 181 m |
| Beam | 25 m |
| Cruising speed | 18.0 kn |
Florida Cruise from Miami to San Francisco — 19 Days
18 nights · Florida · Departs Miami (USA) · Visiting Cabo Rojo-Pedernales, Cartagena Colombia, Panama Canal, Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco · Aboard Azamara Cruises on the Azamara Quest

Image courtesy of Azamara Cruises ©
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Day 1
Miami, USA
Miami rewards travelers who look beyond its cruise terminals. South Beach pairs pastel Art Deco hotels with Ocean Drive; Little Havana serves Cuban coffee and music along Calle Ocho. The Pérez Art Museum Miami and nearby Design District reveal the city’s creative ambition. For a change of pace, Biscayne Bay and the Everglades place vivid natural landscapes within reach.
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Day 4
Cabo Rojo-Pedernales
At the Dominican Republic’s southwestern edge, Cabo Rojo leads to a coast still defined by space, sea and silence. Here, the reward is not a busy resort strip but the wild scenery of Pedernales. Bahía de las Águilas pairs clear water with a long sweep of pale sand. It lies within Jaragua National Park, part of a protected landscape that rewards unhurried exploration. Distances are considerable and services limited, so plan excursions carefully and bring water, sun protection and patience.
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Day 6
Cartagena Colombia, Colombia
A short ride from Cartagena’s cruise port brings you to its UNESCO-listed historic centre and handsome colonial streets. Inside the old walls, flower-draped balconies, shaded plazas and broad stone lanes lead to cafés, churches and lively markets. Visit Castillo San Felipe de Barajas, the great fortress built to defend the harbor, then explore colorful Getsemaní. Come early, before the midday heat settles over the plazas, and save time for a cool drink beside the Caribbean.
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Day 7
Panama Canal, Panama
Few journeys change your sense of scale like a passage through the Panama Canal. This 50-mile waterway links the Atlantic and Pacific, lifting ships through locks and across Gatun Lake. Watch the gates close, water rise, and a vast vessel move within inches of concrete walls. On deck, the engineering is the spectacle; beyond it, rainforest edges the route. Bring binoculars, and stay outside for the crossing.
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Day 9
Puntarenas
Step ashore in Puntarenas, Costa Rica’s long, narrow port city on the Pacific coast. From here, rainforest reserves, coffee country and the Nicoya Peninsula lie within reach. Walk the waterfront promenade for seafood and views across the Gulf of Nicoya. Or head inland to Monteverde’s cloud forest. Plan one excursion and allow time for the road; Puntarenas is best enjoyed at an unhurried pace.
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Day 11
Puerto Quetzal, Guatemala
Puerto Quetzal is Guatemala’s Pacific gateway, a working port backed by volcanic highlands. Most visitors head inland to Antigua, where cobbled streets, pastel façades and church ruins preserve a distinctive colonial setting. The drive takes roughly 90 minutes, depending on traffic. Closer to the coast, excursions visit fishing villages and black-sand beaches. Choose Antigua for architecture and history, or stay coastal for a closer look at everyday life in Guatemala.
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Day 14
Puerto Vallarta, Mexico
Puerto Vallarta sits between the Sierra Madre mountains and Banderas Bay. That setting brings jungle-clad slopes, broad beaches and memorable Pacific views. Begin in the historic center, where cobbled streets lead to the landmark Church of Our Lady of Guadalupe. Follow the Malecón, a seafront promenade lined with sculptures, cafés and galleries. For a taste of the coast, settle in for fresh seafood and watch the bay.
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Day 17
San Diego, USA
San Diego makes an easy first impression: a working harbor, sunlit waterfront and Pacific air. From the cruise terminal, the USS Midway Museum and lively Embarcadero are close at hand. Balboa Park brings world-class museums, gardens and the San Diego Zoo together in one grand setting. In the Gaslamp Quarter, Victorian façades frame restaurants and bars. Nearby neighborhoods reveal Mexican heritage and coastal ease.
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Day 19
San Francisco, USA
San Francisco rewards visitors who look beyond the postcard. Ride a cable car over steep streets, then explore Chinatown, North Beach, or the Ferry Building’s stalls. The Golden Gate Bridge frames the bay, while Alcatraz offers a stark look at the city’s past. For a quieter hour, walk the waterfront or cross to Sausalito by ferry. Few ports make a day ashore feel so varied—and so distinctly Californian.
Azamara Quest Cruises
- 11 Days One-Way from Buenos Aires to Rio De Janeiro
- 11 Days One-Way from Civitavecchia-Rome to Lisbon
- 11 Days One-Way from Copenhagen to Stockholm
- 11 Days One-Way from Lisbon to Tarragona
- 11 Days One-Way from Panama City to Valparaiso-Santiago
- 11 Days One-Way from Stockholm to Copenhagen
- 11 Days One-Way from Valparaiso-Santiago to Ushuaia
- 11 Days Copenhagen, Denmark Round Trip
- 11 Days Piraeus-Athens, Greece Round Trip
- 12 Days One-Way from Barcelona to Venice
- 12 Days One-Way from Lisbon to Portsmouth UK
- 12 Days One-Way from Portsmouth UK to Leith-Edinburgh
- 12 Days One-Way from Portsmouth UK to Lisbon
- 12 Days One-Way from Venice to Piraeus-Athens
- 12 Days Miami, USA Round Trip
- 12 Days Piraeus-Athens, Greece Round Trip
- 13 Days One-Way from Boston to Montreal
- 13 Days One-Way from Copenhagen to Portsmouth UK
- 13 Days One-Way from Miami to Lisbon
- 13 Days One-Way from Montreal to Boston
- 13 Days One-Way from Montreal to New York
- 13 Days One-Way from New York to Montreal
- 13 Days One-Way from Portsmouth UK to Reykjavik
- 13 Days One-Way from Ushuaia to Buenos Aires
- 13 Days Portsmouth Uk, United Kingdom Round Trip
- 14 Days One-Way from Incheon to Tokyo
- 14 Days One-Way from Malaga to Miami
- 13 Days One-Way from Rio De Janeiro to Bridgetown
- 15 Days One-Way from Hong Kong to Incheon
- 15 Days One-Way from London-Tilbury to Copenhagen
- 15 Days One-Way from Papeete to Auckland
- 15 Days Bridgetown, Barbados Round Trip
- 15 Days San Juan, Puerto Rico Round Trip
- 16 Days One-Way from Auckland to Sydney
- 16 Days One-Way from Copenhagen to Portsmouth UK
- 16 Days Bridgetown, Barbados Round Trip
- 16 Days San Juan, Puerto Rico Round Trip
- 17 Days One-Way from Reykjavik to New York
- 17 Days One-Way from Tarragona to Civitavecchia-Rome
- 17 Days One-Way from Villefranche-Sur-Mer to Venice
- 18 Days One-Way from Leith-Edinburgh to Copenhagen
- 18 Days One-Way from New York to Bridgetown
- 18 Days One-Way from San Diego to Miami
- 18 Days One-Way from San Juan to Miami
- 18 Days One-Way from Tokyo to Vancouver
- 19 Days One-Way from Miami to London-Tilbury
- 19 Days One-Way from San Francisco to Papeete
- 19 Days One-Way from Singapore to Hong Kong
- 20 Days One-Way from Miami to Barcelona
- 20 Days One-Way from Miami to Valparaiso-Santiago
- 20 Days One-Way from Sydney to Singapore
- 22 Days One-Way from Civitavecchia-Rome to Portsmouth UK
- 22 Days One-Way from Piraeus-Athens to Miami
- 22 Days One-Way from Portsmouth UK to Tarragona
- 23 Days One-Way from Valparaiso-Santiago to Buenos Aires
- 24 Days One-Way from Portsmouth UK to Leith-Edinburgh
- 25 Days One-Way from New York to San Juan
- 25 Days One-Way from Buenos Aires to Bridgetown
- 26 Days One-Way from Copenhagen to Portsmouth UK
- 28 Days One-Way from Miami to Civitavecchia-Rome
- 29 Days One-Way from Bridgetown to Valparaiso-Santiago
- 29 Days One-Way from Portsmouth UK to New York
- 30 Days One-Way from Barcelona to Portsmouth UK
- 32 Days One-Way from Barcelona to Piraeus-Athens
- 34 Days One-Way from Buenos Aires to Miami
- 35 Days One-Way from Stockholm to Lisbon
- 36 Days One-Way from San Diego to London-Tilbury
- 39 Days One-Way from Piraeus-Athens to Miami
- 42 Days One-Way from Miami to Buenos Aires
- 44 Days One-Way from Copenhagen to New York
- 49 Days One-Way from San Francisco to Sydney
- 49 Days One-Way from Valparaiso-Santiago to Bridgetown
- 58 Days One-Way from Valparaiso-Santiago to Miami
- 68 Days One-Way from Miami to Bridgetown
- 8 Days One-Way from Bridgetown to San Juan
- 8 Days One-Way from Civitavecchia-Rome to Venice
- 8 Days One-Way from Lisbon to Barcelona
- 8 Days One-Way from Saigon to Hong Kong
- 8 Days One-Way from San Juan to Bridgetown
- 8 Days One-Way from Tarragona to Villefranche-Sur-Mer
- 8 Days One-Way from Vancouver to San Diego
- 8 Days Piraeus-Athens, Greece Round Trip
- 77 Days Miami, USA Round Trip
- 80 Days One-Way from Stockholm to Piraeus-Athens
- 9 Days One-Way from Barcelona to Civitavecchia-Rome
- 9 Days One-Way from Miami to Panama City
- 9 Days One-Way from Piraeus-Athens to Malaga
- 9 Days One-Way from San Juan to Bridgetown
- 87 Days One-Way from San Francisco to Hong Kong
- 10 Days One-Way from Bridgetown to Miami
- 10 Days One-Way from New York to San Juan
- 10 Days One-Way from Reykjavik to Copenhagen
- 10 Days One-Way from Singapore to Saigon
- 10 Days One-Way from Venice to Piraeus-Athens
- 10 Days One-Way from Villefranche-Sur-Mer to Civitavecchia-Rome
- 91 Days One-Way from Sydney to San Diego
Published September 3, 2026
Last updated October 3, 2026
Author: J. Richard
Cruise Disclosure
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