Portugal Cruise from Lisbon to Barcelona — 28 Days

27 nights · Portugal · Departs Lisbon (Portugal) · Visiting Portimao, Cadiz, Valencia, Port Mahon, Ajaccio, Livorno, Civitavecchia-Rome, Salerno, Siracusa, Valletta, Souda-Chania, Nafplio, Syros Island, Piraeus-Athens, Naxos Island, Monemvasia, La Goulette-Tunis, Cagliari, Monte Carlo, Toulon, Barcelona · Aboard Crystal Cruises on the Crystal Serenity

Crystal Cruises logo
Cruise lineCrystal Cruises
ShipCrystal Serenity
Duration27 nights
Port calls22
Departures1 sailings
From fare$17,000 per person
Year built2003
Guests740
Cabins347
Crew655
Length250 m
Beam32 m
Cruising speed21.0 kn
  1. Day 1

    Lisbon, Portugal

    Lisbon is a city best approached with time and comfortable shoes. Its seven hills rise above the Tagus, linking tiled lanes, grand squares and viewpoints with wide river views. In Alfama, narrow streets preserve the feel of old Lisbon. In Belém, the Jerónimos Monastery and Tower recall Portugal’s age of discovery. Pause for coffee and a warm pastel de nata between sights.

  2. Day 2

    Portimao, Portugal

    Portimão sits where the Arade River meets the Atlantic, in Portugal’s sunlit Algarve. From the quay, Praia da Rocha’s ochre cliffs and broad sands are close at hand. In the old town, tiled façades and cafés frame the Igreja de Nossa Senhora da Conceição. Choose fresh sardines at the waterfront, or cross the river to Ferragudo for a quieter village view. Portimão makes an easy base for exploring the Algarve’s coast without sacrificing a genuine working-town feel.

  3. Day 3

    Cadiz, Spain

    Cádiz is one of Europe’s oldest continuously inhabited cities, set on a narrow peninsula where Atlantic light reaches every street. Its compact old quarter is made for unhurried exploration, with watchtowers, shaded plazas and the cathedral’s golden dome. At the Mercado Central, fishmongers display the day’s catch; nearby taverns serve fino sherry and local seafood. Beyond the walls, La Caleta beach and the seafront promenade offer a bracing taste of Cádiz’s maritime life.

  4. Day 5

    Valencia, Spain

    Valencia rewards travellers who look beyond its waterfront. Spain’s third-largest city pairs a handsome old centre with the bold architecture of the City of Arts and Sciences. Visit the Central Market for local produce, then follow the Turia Gardens towards the coast. Paella has deep roots here; seek it in its birthplace, not merely on the menu. With efficient transport and a compact historic core, Valencia is easy to explore at your own pace.

  5. Day 6

    Port Mahon, Spain

    Mahón sits at the head of one of the world’s largest natural harbours, a deep-water inlet that shaped Menorca’s history. From the waterfront, climb to the old town for Georgian façades, lively markets and views across the port. Menorca’s British-era influence appears in its architecture and in gin, still distilled locally and served with lemonade. Allow time to explore beyond Mahón: the island’s quiet coves, prehistoric stone monuments and clear waters reward an unhurried visit.

  6. Day 7

    Ajaccio, France

    Ajaccio brings Corsica’s character within easy reach of the quay. France’s island capital pairs a sheltered gulf with pastel façades, a lively old town and mountain ridges above the harbor. Napoleon Bonaparte was born here in 1769; his birthplace is now a museum. From Place Foch, browse the market before following narrow lanes to the cathedral and waterfront cafés. Allow time for a swim or a scenic drive along the coast, where coves and clear water reward exploration.

  7. Day 8

    Livorno, Italy

    Livorno rewards those who look beyond the cruise terminal. Its canals, built in the style of Venice, wind through historic Venezia Nuova. The seafront promenade leads to Terrazza Mascagni, where black-and-white paving frames the sea. At Mercato Centrale, locals shop beneath a vast iron-and-glass roof. Try cacciucco, the city’s rich fish stew. Florence and Pisa are within reach, but Livorno merits time of its own.

  8. Day 9

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  9. Day 10

    Salerno, Italy

    Salerno puts southern Italy within easy reach, with ferries and roads leading toward the Amalfi Coast. Yet the city rewards a closer look: its old lanes gather around the handsome Duomo di San Matteo. Inside, bronze doors and a richly decorated crypt recall Salerno’s medieval importance as a center of learning. Climb to Arechi Castle for broad views across the Gulf, or venture inland to the Greek temples at Paestum.

  10. Day 11

    Siracusa, Italy

    Siracusa rewards visitors who look beyond its handsome waterfront. On Ortigia, the old island heart, Greek temples, Baroque palaces and lively markets sit within an easy walk. Across the channel, Neapolis Archaeological Park preserves a Greek theatre, Roman amphitheatre and the famed Ear of Dionysius. Pause for granita or fresh seafood, then watch the light soften over the Ionian Sea.

  11. Day 12

    Valletta, Malta

    Valletta makes a powerful first impression, its honey-coloured walls rising above Grand Harbour. Founded by the Knights of St John in 1566, Malta’s compact capital rewards exploration on foot. Enter St John’s Co-Cathedral for Caravaggio’s monumental paintings, then follow Republic Street to cafés, palaces and the Upper Barrakka Gardens. From the terraces, watch ferries cross the harbour and look towards the Three Cities. Allow time for steep lanes and quiet side streets.

  12. Day 14

    Souda-Chania, Greece

    Souda Bay places you within easy reach of Chania, one of Crete’s most compelling historic towns. A short drive leads to Chania’s Venetian harbour, with its lighthouse, waterfront cafés and narrow lanes. On the Akrotiri peninsula, monasteries and coastal views share the landscape with the Allied war cemetery overlooking Souda Bay. Make time for Cretan cooking, distinguished by fine olive oil, local cheeses and wild herbs.

  13. Day 15

    Nafplio, Greece

    Nafplion is the Peloponnese at its most inviting: a seafront town shaped by Venetian, Ottoman and Greek histories. In the old quarter, cobbled lanes lead to Syntagma Square, lined with historic façades and cafés. Above the rooftops, Palamidi Fortress commands the view; offshore, Bourtzi guards the harbor. Come ashore for a compact, walkable city, then linger over lunch beside the water.

  14. Day 16

    Syros Island, Greece

    Above Ermoupoli’s busy harbor, Áno Sýros keeps the quieter face of Syros. Its medieval lanes climb toward the Catholic Cathedral of Saint George, past whitewashed houses and small tavernas. Go on foot in shoes with grip, pausing for views across the Aegean and down to the neoclassical capital. This is a place for unhurried exploring, not a beach day.

  15. Day 17

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

  16. Day 18

    Naxos Island, Greece

    Naxos is the largest island in the Cyclades, yet its pleasures feel refreshingly unhurried. From the harbor, the marble Portara frames the sea, while the Venetian Kastro rises above the old town’s narrow lanes. Beyond town, villages such as Halki reveal Byzantine churches, citrus groves, and the island’s distinctive kitron liqueur. Golden beaches, mountain roads, and excellent tavernas make Naxos worth exploring beyond the waterfront.

  17. Day 19

    Monemvasia, Greece

    Monemvasia rises from the sea as a sheer rock, joined to the Peloponnese by a narrow causeway. Step through its medieval gate into a stone-built town of vaulted lanes, Byzantine churches and Venetian-era mansions. Cars stay outside the lower town, leaving its steep alleys to walkers. Climb to the ruined upper fortress for wide views across the Aegean, then return for local wine and seafood.

  18. Day 21

    La Goulette-Tunis, Tunisia

    La Goulette is Tunisia’s principal cruise gateway, set on the Mediterranean just northeast of Tunis. The capital’s old medina, Carthage’s ruins and Sidi Bou Said’s white-and-blue lanes are all within reach. Choose Roman history, Ottoman-era streets or cafés overlooking the sea. Plan around traffic: these sights lie in different directions, and each merits an unhurried visit.

  19. Day 22

    Cagliari, Italy

    Cagliari rewards those who look beyond the waterfront. Sardinia’s capital rises above the Gulf of Angels, its old Castello quarter perched over a working port. Walk the bastions for broad views, then explore the Roman amphitheatre carved into limestone. Below town, Poetto’s long beach meets salt lagoons where flamingos feed. Return for fregola with seafood or bottarga, the island’s prized cured mullet roe.

  20. Day 23

    Ajaccio, France

    Ajaccio brings Corsica’s character within easy reach of the quay. France’s island capital pairs a sheltered gulf with pastel façades, a lively old town and mountain ridges above the harbor. Napoleon Bonaparte was born here in 1769; his birthplace is now a museum. From Place Foch, browse the market before following narrow lanes to the cathedral and waterfront cafés. Allow time for a swim or a scenic drive along the coast, where coves and clear water reward exploration.

  21. Day 24

    Monte Carlo, Monaco

    Monte Carlo makes a striking first impression, with superyachts in Port Hercule and the Alps rising behind the coast. A short walk leads to Casino Square, where Belle Époque architecture frames the famous casino and designer boutiques. For a quieter contrast, climb to Monaco-Ville for the Prince’s Palace, cathedral and views across the harbor. The principality is compact and easy to explore on foot, though its steep streets reward comfortable shoes.

  22. Day 26

    Toulon, France

    Toulon is a working Mediterranean port, framed by limestone hills and one of Europe’s finest natural harbours. Look beyond the waterfront to the old town, where Cours Lafayette’s market fills the street with Provençal produce. For a wider view, ride the cable car up Mont Faron, then visit its memorial to the 1944 Allied landings. Nearby, the Îles d’Hyères, local beaches and cafés offer an easy-paced taste of coastal Provence.

  23. Day 28

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

Crystal Serenity Cruises

Published August 15, 2026
Last updated October 3, 2026
Author: J. Richard


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