Argentina Cruise from Buenos Aires to Port Everglades — 42 Days

41 nights · Argentina · Departs Buenos Aires (Argentina) · Visiting Punta del Este, Puerto Madryn, Port Stanley, Ushuaia, Punta Arenas, Chilean Fjords, Puerto Chacabuco, Chiloe Island Chile, Puerto Montt, Valparaiso-Santiago, Coquimbo, Iquique, Pisco, Callao-Lima, Salaverry-Trujillo, Guayaquil, Panama City, Panama Canal, Puerto Limon, Roatan Island, Santo Tomas de Castilla, Belize City, Cozumel, Progreso, Fort Lauderdale · Aboard Crystal Cruises on the Crystal Serenity

Crystal Cruises logo
Cruise lineCrystal Cruises
ShipCrystal Serenity
Duration41 nights
Port calls26
Departures1 sailings
From fare$18,020 per person
Year built2003
Guests740
Cabins347
Crew655
Length250 m
Beam32 m
Cruising speed21.0 kn
  1. Day 1

    Buenos Aires, Argentina

    Buenos Aires is a city of broad boulevards, grand theatres and late dinners, with a distinctly Argentine pulse. From the port, explore La Boca’s vivid lanes or San Telmo’s antique market. Recoleta adds belle époque architecture; Palermo brings leafy parks, galleries and restaurants. Make time for a steakhouse and a tango performance, two traditions that give the capital its lasting character.

  2. Day 2

    Punta del Este, Uruguay

    Punta del Este makes a polished first impression, yet its appeal reaches beyond its famous beaches. Set on a narrow peninsula between the Atlantic and the Río de la Plata, Uruguay’s resort town invites exploration. At Playa Brava, La Mano’s giant fingers emerge from the sand. West of town, Carlos Páez Vilaró’s Casapueblo combines sculptural architecture with a museum and sea views. Come for the light, stay for seafood and Uruguay’s easygoing pace.

  3. Day 4

    Puerto Madryn, Argentina

    Puerto Madryn sits on sheltered Golfo Nuevo, where Patagonia’s coast meets the Atlantic. From here, Peninsula Valdés, a UNESCO World Heritage site, offers encounters with southern right whales, elephant seals and sea lions. Between June and December, whales gather in the gulf; Magellanic penguins nest at Punta Tombo farther south. In town, Welsh heritage and a waterfront promenade offer a quieter counterpoint to Patagonia’s wild scale.

  4. Day 6

    Port Stanley

    Stanley sits on East Falkland, where the South Atlantic’s wide skies frame a compact, distinctly British capital. Its painted houses, tidy gardens and sheltered harbor contrast with the islands’ open, windswept terrain. Visit Christ Church Cathedral and its whalebone arch, then explore the Falkland Islands Museum for local history. Beyond town, guided excursions reach penguin colonies and dramatic coastal landscapes.

  5. Day 8

    Ushuaia, Argentina

    Ushuaia sits between the Beagle Channel and the snow-streaked Martial Mountains, at Argentina’s far southern edge. Its harbor has long served as a gateway to Antarctica, while the town itself rewards a slower look. Ride the End of the World Train into Tierra del Fuego National Park, or tour the former prison museum. Here, wild landscapes begin just beyond the last streets.

  6. Day 9

    Punta Arenas, Chile

    At the edge of the Strait of Magellan, Punta Arenas feels like a city built for crossing oceans. Its broad avenues and ornate mansions reflect the fortunes of sheep farming and trade. The Maggiorino Borgatello Museum traces Patagonia’s natural and human history. Climb Cerro de la Cruz for views across the harbor and rooftops. From here, boats reach Magdalena Island, home to thousands of Magellanic penguins.

  7. Day 13

    Chilean Fjords, Chile

    South of Puerto Montt, Chile’s fjords form a maze of islands, channels and snowbound peaks. Glaciers descend from the Southern Patagonian Ice Field, while temperate rainforest reaches the water’s edge. Watch for dolphins and seabirds from deck; shore landings, where offered, reveal remote coastlines at close range. These are working waterways as well as wild scenery, best appreciated slowly, with camera ready and plans flexible.

  8. Day 14

    Puerto Chacabuco, Chile

    Puerto Chacabuco is a working port on Chile’s remote Aysén coast, where forested mountains rise from the fjords. Most visitors come for the journey inland: Coyhaique, the regional capital, lies about 80 kilometres away by road. From there, Patagonia opens into river valleys, glaciers and the Río Simpson National Reserve. Near the harbour, watch daily life unfold in one of Chile’s least-visited regions.

  9. Day 15

    Chiloe Island Chile, Chile

    Chiloé rewards travelers who value character over spectacle. Its green hills, sheltered coves and wooden churches reveal a Chile apart from the mainland. In Castro, brightly painted palafitos stand above the tidal waterfront, while the island’s UNESCO-listed churches preserve centuries of local craft. Sample curanto, a traditional feast of shellfish, meat and potatoes, or browse Dalcahue’s artisan market. Allow time for the landscapes; distances are modest, but roads and ferries set an unhurried pace.

  10. Day 16

    Puerto Montt, Chile

    Puerto Montt is Chile’s working gateway to the Lake District, where the Andes rise above deep blue water. At the waterfront, fish stalls and seafood kitchens make the city’s maritime life easy to taste. Browse Angelmó market for smoked salmon, shellfish and local crafts, then look north toward the snow-covered cone of Osorno. Beyond town, lakes, forests and Chiloé’s distinctive island culture reward travelers who venture farther.

  11. Day 18

    Valparaiso-Santiago, Chile

    Valparaíso is Chile’s most characterful port, a steep-sided city rising above the Pacific in a mosaic of color. Ride a historic funicular into the hills, where murals, stairways and bright houses reward unhurried exploration. In the UNESCO-listed historic quarter, grand 19th-century architecture recalls the era when ships rounded Cape Horn. Visit La Sebastiana, poet Pablo Neruda’s house, then return to the waterfront for fresh seafood and broad Pacific views.

  12. Day 20

    Coquimbo, Chile

    Coquimbo opens onto a broad Pacific bay, where fishing boats share the water with visiting ships. Its working-port character feels distinct from neighbouring La Serena, whose colonial churches and long beaches lie just north. Climb to the Cross of the Third Millennium for sweeping coastal views, then seek fresh seafood along the waterfront. Inland, the Elqui Valley’s pisco distilleries and clear skies make an appealing day trip.

  13. Day 22

    Iquique, Chile

    Iquique lies between the Pacific and the Atacama, where desert meets a broad, surf-lined coast. Its historic centre recalls the nitrate boom, with ornate wooden façades along Baquedano Street. Plaza Prat’s clock tower anchors the district. Browse the ZOFRI free-trade zone, or linger over seafood by the waterfront. Inland, the UNESCO-listed Humberstone and Santa Laura saltpeter works reveal the harsh history behind the city’s prosperity.

  14. Day 24

    Pisco, Peru

    Pisco is Peru’s gateway to a stark coast where desert, ocean and wildlife meet. Nearby Paracas offers boat trips to the Ballestas Islands, where sea lions, Humboldt penguins and seabirds gather. The peninsula’s Paracas Candelabra, etched into a sandy hillside, is best seen from the water. In town, discover the grape brandy that shares Pisco’s name; the celebrated Nazca Lines lie farther inland to the south.

  15. Day 25

    Callao-Lima, Peru

    Callao is Peru’s working maritime gateway, but its appeal extends beyond the harbour. From here, Lima’s historic centre and museums are within reach. In Callao, explore the imposing Real Felipe Fortress, built to defend the port, then visit La Punta for Pacific views. Stay for ceviche and discover a city shaped by trade, naval history and the ocean.

  16. Day 26

    Salaverry-Trujillo, Peru

    Salaverry opens Peru’s northern coast, where ancient kingdoms and Spanish-era streets share the day. Trujillo, founded in 1534, lies about 14 kilometres inland and rewards a walk through its historic centre. Nearby, Chan Chan, the vast adobe capital of the Chimú, reveals a civilization that flourished before the Inca. At Huaca de la Luna, vivid painted reliefs bring the Moche world into view.

  17. Day 28

    Guayaquil, Ecuador

    Guayaquil is Ecuador’s largest city, a river port where the Guayas meets the Pacific-facing estuary. Start along the Malecón 2000, the broad waterfront promenade lined with gardens, museums and cafés. Then climb the steps of Las Peñas to Santa Ana Hill for rooftop views across the city and river. At Parque Seminario, iguanas roam beneath the palms in the heart of downtown. Guayaquil rewards a curious day ashore with lively streets, colonial-era façades and a distinctly coastal rhythm.

  18. Day 30

    Panama City, Panama

    Balboa sits at the Pacific entrance to the Panama Canal, where ocean-going ships begin their passage between continents. From the port, Panama City’s skyline rises beyond the canal’s working waters. Visit Casco Viejo for restored colonial streets, independent cafés and views across the bay. Or follow the Amador Causeway toward the Biomuseo and sweeping views of ships awaiting transit. Balboa rewards travelers who look beyond the canal to a capital shaped by trade, history and the sea.

  19. Day 32

    Panama Canal, Panama

    Few journeys change your sense of scale like a passage through the Panama Canal. This 50-mile waterway links the Atlantic and Pacific, lifting ships through locks and across Gatun Lake. Watch the gates close, water rise, and a vast vessel move within inches of concrete walls. On deck, the engineering is the spectacle; beyond it, rainforest edges the route. Bring binoculars, and stay outside for the crossing.

  20. Day 33

    Puerto Limon

    Puerto Limón is Costa Rica’s Caribbean gateway, where Afro-Caribbean heritage meets a lush tropical coast. Visit Cahuita National Park for coral reefs and rainforest trails, or travel inland through banana country toward the jungle. Limón’s markets and waterfront offer a closer look at the region’s food, music and daily life. For a longer excursion, explore Tortuguero’s canals by boat and watch for wildlife in the Caribbean lowlands.

  21. Day 35

    Roatan Island, Honduras

    Roatán, the largest of Honduras’s Bay Islands, sits beside the Mesoamerican Reef, the world’s second-largest barrier reef system. That proximity makes clear water and coral gardens the island’s chief attractions, whether you snorkel or dive. Follow the coast between West End’s lively shops and West Bay’s broad, pale-sand beach. For a quieter view of island life, head east toward villages, mangroves, and viewpoints above the Caribbean.

  22. Day 36

    Santo Tomas de Castilla, Guatemala

    Santo Tomás de Castilla brings you to Guatemala’s Caribbean coast, where tropical forest meets the broad waters of Amatique Bay. The modern port lies beside Puerto Barrios, a working town with a distinctly local rhythm. Beyond the waterfront, boat journeys follow the Río Dulce toward Livingston and its Garífuna heritage. Inland, the carved Maya monuments of Quiriguá reward travelers willing to trade the coast for history.

  23. Day 37

    Belize City, Belize

    Belize City is the country’s largest city and maritime gateway, set on the Caribbean coast. It stands at the mouth of Haulover Creek, where cruise ships anchor offshore. Tenders bring visitors to the Fort Street Tourism Village. From here, explore colonial-era landmarks and local markets, or travel inland to Maya sites and cave systems. Belize’s barrier reef offers excellent options for snorkelling and diving.

  24. Day 38

    Cozumel, Mexico

    Cozumel, off Mexico’s Yucatán Peninsula, pairs clear Caribbean water with a lively island town. San Miguel de Cozumel offers cafés, shops and a waterfront promenade within easy reach of the cruise piers. Beyond town, reef excursions reveal why divers travel here, while San Gervasio preserves the island’s Mayan history. Choose a beach day, a guided snorkel or a drive around the coast; each shows a different side of Cozumel.

  25. Day 40

    Progreso, Mexico

    Progreso gives you an easy first look at the Yucatán beyond the ship. Its long pier reaches the coast, where a broad malecón, seafood cafés and Gulf waters set an unhurried pace. Head inland to Mérida for colonial streets and Yucatecan cooking, or visit Dzibilchaltún, a Maya archaeological site near town. Progreso is a practical base for exploring the peninsula, with history and local flavor within reach.

  26. Day 42

    Fort Lauderdale, USA

    Port Everglades puts Fort Lauderdale within easy reach of the city’s waterways, beaches and cultural attractions. A short drive brings you to Las Olas Boulevard, where galleries, restaurants and boutiques line a walkable stretch. Visit the Bonnet House Museum & Gardens for a glimpse of old Florida, or head west toward the Everglades. Fort Lauderdale’s broad Atlantic beaches offer an easy counterpoint to the city’s lively dining scene.

Crystal Serenity Cruises

Published September 14, 2026
Last updated October 3, 2026
Author: J. Richard


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