| Cruise line | Holland America |
|---|---|
| Ship | ms Nieuw Amsterdam |
| Duration | 21 nights |
| Port calls | 11 |
| Departures | 1 sailings |
| From fare | $5,169 per person |
| Year built | 2010 |
| Guests | 2527 |
| Cabins | 1053 |
| Crew | 929 |
| Length | 285 m |
| Beam | 32 m |
| Cruising speed | 24.0 kn |
Chile Cruise from San Antonio to Buenos Aires — 22 Days
21 nights · Chile · Departs San Antonio (Chile) · Visiting Puerto Montt, Puerto Chacabuco, Punta Arenas, Ushuaia, Cape Horn, Port Stanley, Puerto Madryn, Punta del Este, Montevideo, Buenos Aires · Aboard Holland America on the ms Nieuw Amsterdam

Image courtesy of Holland America ©
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Day 1
San Antonio, Chile
San Antonio is Chile’s largest commercial port, a working coastal city with a distinctly local rhythm. Its appeal extends beyond the docks: Santiago lies about 110 kilometres inland. Valparaíso is north, while the Casablanca Valley’s wineries offer a rewarding excursion nearby. Begin at the fish market and waterfront, or venture to Santiago, Valparaíso and Casablanca’s vineyards.
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Day 3
Puerto Montt, Chile
Puerto Montt is Chile’s working gateway to the Lake District, where the Andes rise above deep blue water. At the waterfront, fish stalls and seafood kitchens make the city’s maritime life easy to taste. Browse Angelmó market for smoked salmon, shellfish and local crafts, then look north toward the snow-covered cone of Osorno. Beyond town, lakes, forests and Chiloé’s distinctive island culture reward travelers who venture farther.
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Day 4
Puerto Chacabuco, Chile
Puerto Chacabuco is a working port on Chile’s remote Aysén coast, where forested mountains rise from the fjords. Most visitors come for the journey inland: Coyhaique, the regional capital, lies about 80 kilometres away by road. From there, Patagonia opens into river valleys, glaciers and the Río Simpson National Reserve. Near the harbour, watch daily life unfold in one of Chile’s least-visited regions.
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Day 7
Punta Arenas, Chile
At the edge of the Strait of Magellan, Punta Arenas feels like a city built for crossing oceans. Its broad avenues and ornate mansions reflect the fortunes of sheep farming and trade. The Maggiorino Borgatello Museum traces Patagonia’s natural and human history. Climb Cerro de la Cruz for views across the harbor and rooftops. From here, boats reach Magdalena Island, home to thousands of Magellanic penguins.
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Day 8
Ushuaia, Argentina
Ushuaia sits between the Beagle Channel and the snow-streaked Martial Mountains, at Argentina’s far southern edge. Its harbor has long served as a gateway to Antarctica, while the town itself rewards a slower look. Ride the End of the World Train into Tierra del Fuego National Park, or tour the former prison museum. Here, wild landscapes begin just beyond the last streets.
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Day 9
Cape Horn, Chile
Few names in navigation carry the weight of Cape Horn. On Hornos Island, Chile, it marks the southern end of the Tierra del Fuego archipelago. Here, Atlantic and Pacific waters meet near the Drake Passage. Landing depends on weather and sea conditions, so many visitors view the island from ship. Ashore, a lighthouse, small chapel and Albatross Monument recall the mariners who navigated this formidable route.
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Day 16
Port Stanley
Stanley sits on East Falkland, where the South Atlantic’s wide skies frame a compact, distinctly British capital. Its painted houses, tidy gardens and sheltered harbor contrast with the islands’ open, windswept terrain. Visit Christ Church Cathedral and its whalebone arch, then explore the Falkland Islands Museum for local history. Beyond town, guided excursions reach penguin colonies and dramatic coastal landscapes.
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Day 18
Puerto Madryn, Argentina
Puerto Madryn sits on sheltered Golfo Nuevo, where Patagonia’s coast meets the Atlantic. From here, Peninsula Valdés, a UNESCO World Heritage site, offers encounters with southern right whales, elephant seals and sea lions. Between June and December, whales gather in the gulf; Magellanic penguins nest at Punta Tombo farther south. In town, Welsh heritage and a waterfront promenade offer a quieter counterpoint to Patagonia’s wild scale.
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Day 20
Punta del Este, Uruguay
Punta del Este makes a polished first impression, yet its appeal reaches beyond its famous beaches. Set on a narrow peninsula between the Atlantic and the Río de la Plata, Uruguay’s resort town invites exploration. At Playa Brava, La Mano’s giant fingers emerge from the sand. West of town, Carlos Páez Vilaró’s Casapueblo combines sculptural architecture with a museum and sea views. Come for the light, stay for seafood and Uruguay’s easygoing pace.
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Day 21
Montevideo, Uruguay
Uruguay’s capital faces the broad Río de la Plata, where a working port and long waterfront set the city’s pace. Walk the cobbled lanes of Ciudad Vieja to find colonial façades, galleries, and the lively stalls of Mercado del Puerto. Beyond the historic center, the Rambla traces roughly 22 kilometers of shoreline, drawing locals to cafés, beaches, and sunset views. Come for grilled beef, Tannat wine, and a capital whose relaxed rhythm rewards a day spent on foot.
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Day 22
Buenos Aires, Argentina
Buenos Aires is a city of broad boulevards, grand theatres and late dinners, with a distinctly Argentine pulse. From the port, explore La Boca’s vivid lanes or San Telmo’s antique market. Recoleta adds belle époque architecture; Palermo brings leafy parks, galleries and restaurants. Make time for a steakhouse and a tango performance, two traditions that give the capital its lasting character.
ms Nieuw Amsterdam Cruises
- 12 Days Vancouver, Canada Round Trip
- 13 Days Fort Lauderdale, USA Round Trip
- 15 Days One-Way from Buenos Aires to San Antonio
- 15 Days One-Way from San Antonio to Buenos Aires
- 15 Days Vancouver, Canada Round Trip
- 17 Days One-Way from San Diego to Fort Lauderdale
- 17 Days Fort Lauderdale, USA Round Trip
- 18 Days One-Way from Fort Lauderdale to San Diego
- 18 Days One-Way from San Antonio to Fort Lauderdale
- 20 Days Fort Lauderdale, USA Round Trip
- 22 Days One-Way from Buenos Aires to San Antonio
- 22 Days One-Way from Fort Lauderdale to Vancouver
- 22 Days One-Way from San Diego to San Antonio
- 22 Days One-Way from Vancouver to Fort Lauderdale
- 22 Days Fort Lauderdale, USA Round Trip
- 27 Days One-Way from Vancouver to San Antonio
- 32 Days One-Way from Buenos Aires to Fort Lauderdale
- 36 Days One-Way from San Diego to Buenos Aires
- 5 Days One-Way from San Diego to Vancouver
- 41 Days One-Way from Vancouver to Buenos Aires
- 6 Days One-Way from Vancouver to San Diego
- 7 Days Vancouver, Canada Round Trip
- 8 Days One-Way from Vancouver to Whittier
- 8 Days One-Way from Whittier to Vancouver
- 8 Days Fort Lauderdale, USA Round Trip
- 8 Days Vancouver, Canada Round Trip
- 9 Days Vancouver, Canada Round Trip
- 10 Days Fort Lauderdale, USA Round Trip
Published September 20, 2026
Last updated October 3, 2026
Author: J. Richard
Cruise Disclosure
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