Spain Cruise from Barcelona to Piraeus — 22 Days

21 nights · Spain · Departs Barcelona (Spain) · Visiting Marseille, Livorno, Civitavecchia-Rome, Naples, Corfu Island, Dubrovnik, Kotor, Zadar, Trieste, Rijeka, Split, Santorini Island, Bodrum, Kusadasi, Istanbul, Piraeus-Athens · Aboard Holland America on the ms Oosterdam

Holland America logo
Cruise lineHolland America
Shipms Oosterdam
Duration21 nights
Port calls17
Year built2003
Guests2429
Cabins1012
Crew817
Length285 m
Beam32 m
Cruising speed22.0 kn
  1. Day 1

    Barcelona, Spain

    Barcelona is a Mediterranean port city built on Roman foundations, with Gothic lanes and striking modernist architecture. La Rambla runs from Plaça de Catalunya towards the waterfront and the old town. Gaudí’s Sagrada Família and Park Güell show the city at its most distinctive. Set aside time for a market lunch and a walk through El Born, where medieval streets meet lively cafés. Barcelona’s beaches offer a welcome pause between visits.

  2. Day 2

    Marseille, France

    Marseille is France’s oldest city, founded by Greek settlers around 600 BC, and it still faces the Mediterranean with confidence. Begin at the Vieux-Port, where fishing boats share the waterfront with cafés and ferries bound for nearby islands. Climb to Notre-Dame de la Garde for sweeping views, or explore Le Panier’s narrow lanes and lively squares. The Calanques’ limestone coves lie beyond the city; local markets bring Provençal flavors closer.

  3. Day 3

    Livorno, Italy

    Livorno rewards those who look beyond the cruise terminal. Its canals, built in the style of Venice, wind through historic Venezia Nuova. The seafront promenade leads to Terrazza Mascagni, where black-and-white paving frames the sea. At Mercato Centrale, locals shop beneath a vast iron-and-glass roof. Try cacciucco, the city’s rich fish stew. Florence and Pisa are within reach, but Livorno merits time of its own.

  4. Day 4

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  5. Day 5

    Naples, Italy

    Naples puts its history within reach: the port opens onto a compact city framed by Mount Vesuvius and the bay. UNESCO-listed streets lead to churches, palaces and the everyday theatre of southern Italian life. At the National Archaeological Museum, mosaics and objects from Pompeii and Herculaneum bring the Roman world sharply into focus. Stay close for Neapolitan pizza, or use Naples as a springboard to Pompeii, Herculaneum and Capri.

  6. Day 7

    Corfu Island, Greece

    Corfu rewards visitors who look beyond the beach resorts. Its Old Town, a UNESCO World Heritage site, bears the marks of centuries of Venetian rule. Walk the arcaded Liston, then climb to the Old Fortress for views across the rooftops and Ionian Sea. Beyond town, cypress-lined roads lead to Paleokastritsa’s coves, while the Achilleion palace recalls an imperial past. Allow time for lunch; Corfiot cooking pairs Ionian seafood with Italian and Greek influences.

  7. Day 8

    Dubrovnik, Croatia

    Spend a day inside Dubrovnik’s UNESCO-listed Old Town, best explored on foot. Walk the city walls for close views of fortifications, roofs, and harbor. Then follow Stradun to Rector’s Palace and the Franciscan monastery. Book wall access in advance during busy months, and start early in summer. Mount Srđ offers a higher view, reached by cable car or road. Leave time for side lanes; their quieter corners reveal the city’s daily rhythm.

  8. Day 9

    Kotor, Montenegro

    At the head of Montenegro’s Bay of Kotor, the old town sits beneath steep mountains. Enter through the Sea Gate and follow stone lanes to St Tryphon’s Cathedral. Venetian-era walls frame squares, churches, and cafés within a compact UNESCO-listed center. For a broader view, climb toward San Giovanni Fortress; the steps are demanding. Take water and allow time for the ascent, especially in summer heat. From the harbor, the bay’s changing light makes a memorable arrival and departure.

  9. Day 10

    Zadar, Croatia

    Zadar pairs a compact old town with a clear Adriatic setting. Roman streets, Venetian gates and medieval churches tell the story of a city shaped by centuries of trade. On the seafront, the Sea Organ turns waves into music through stone pipes. Nearby, the Sun Salutation gathers solar energy and shines after dark. Beyond the walls, Nin’s salt pans and the island-dotted coast reward a closer look.

  10. Day 11

    Trieste, Italy

    Trieste rewards travellers who look beyond the waterfront. At the head of the Adriatic, this Italian city carries the marks of centuries under Habsburg rule. Start in Piazza Unità d’Italia, one of Europe’s largest seafront squares, opening directly onto the sea. Visit Miramare Castle, built for Archduke Ferdinand Maximilian, then order espresso in a city shaped by its coffee trade. Trieste is compact and cosmopolitan, with a Roman theatre and grand cafés recalling its Central European past.

  11. Day 13

    Rijeka, Croatia

    Rijeka is Croatia’s working seaport, set at the head of the Kvarner Gulf beneath steep green hills. From the quays, Austro-Hungarian façades and lively Korzo make a compelling first encounter. Visit the Central Market for local produce, then head to hilltop Trsat Castle for views across the harbor and islands. Beyond the waterfront, Roman remains, grand civic buildings, and everyday cafés reveal a city shaped by many eras.

  12. Day 14

    Split, Croatia

    Split is Croatia’s second-largest city, but its heart feels remarkably intimate. Inside Diocletian’s Palace, Roman walls frame cafés, shops and homes. The cathedral and Peristyle recall the emperor’s former residence. Walk the Riva for views across the harbor and its working waterfront. Then climb Marjan Hill for a broad panorama of red roofs and Adriatic islands. Few ports make history so easy to enter on foot.

  13. Day 16

    Santorini Island, Greece

    Few Greek islands make an entrance like Santorini, where whitewashed villages crown a volcanic caldera above the Aegean. Most cruise ships anchor offshore, and tenders land at the old port below Fira. Ride the cable car, or climb the steps, to reach the island’s capital and its celebrated views. Beyond Fira, Oia’s blue domes, the archaeological site of Akrotiri, and volcanic wines reward a longer day ashore.

  14. Day 17

    Bodrum, Turkey

    Bodrum brings the Aegean within reach: a handsome harbor, whitewashed houses and the Crusader-built Castle of St Peter. Its Museum of Underwater Archaeology displays finds recovered from ancient shipwrecks. Explore ancient Halicarnassus, whose Mausoleum was one of the Seven Wonders of the Ancient World. Then settle at a waterfront table for grilled fish and a view across the bay.

  15. Day 18

    Kusadasi, Turkey

    Kuşadası puts the Aegean within reach, with a lively waterfront and one of Turkey’s most celebrated ancient cities nearby. Ephesus lies about 20 kilometres inland, where marble avenues lead to the Library of Celsus and Great Theatre. Back in town, browse the bazaar, then follow the causeway to Pigeon Island and its historic fortress. The harbour-facing promenade offers an easy place to linger over the Aegean light.

  16. Day 19

    Istanbul, Turkey

    Istanbul makes a compelling first impression: minarets rise above the Bosphorus, while ferries cross between Europe and Asia. On the historic peninsula, Hagia Sophia, the Blue Mosque and Topkapi Palace place centuries of empire within walking distance. Istanbul rewards curiosity beyond its landmarks. Browse the Grand Bazaar, linger over Turkish coffee, then take a ferry to the Asian shore. Allow time for traffic and queues; the city’s scale is part of the experience.

  17. Day 22

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

ms Oosterdam Cruises

Published August 24, 2026
Last updated October 11, 2026
Author: J. Richard


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