Florida Cruise from Miami to Panama Canal — 24 Days

23 nights · Florida · Departs Miami (USA) · Visiting Key West, Grand Cayman Island, Santo Tomas de Castilla, Harvest Caye Belize, Cozumel, St Thomas Island USVI, Philipsburg St Maarten, Basseterre St Kitts, Willemstad Curacao, Oranjestad Aruba, Cartagena Colombia, Panama Canal, Panama City · Aboard Oceania Cruises on the Oceania Vista

Oceania Cruises logo
Cruise lineOceania Cruises
ShipOceania Vista
Duration23 nights
Port calls14
Departures1 sailings
From fare$9,499 per person
Year built2023
Guests1469
Cabins613
Crew800
Length251 m
Beam32 m
Cruising speed20.0 kn
  1. Day 1

    Miami, USA

    Miami rewards travelers who look beyond its cruise terminals. South Beach pairs pastel Art Deco hotels with Ocean Drive; Little Havana serves Cuban coffee and music along Calle Ocho. The Pérez Art Museum Miami and nearby Design District reveal the city’s creative ambition. For a change of pace, Biscayne Bay and the Everglades place vivid natural landscapes within reach.

  2. Day 2

    Key West, USA

    Key West rewards travelers who leave the ship and follow the island’s easy pace. At the southern tip of the Florida Keys, this compact city pairs pastel architecture with a maritime past. Visit the Ernest Hemingway Home and Museum, browse Duval Street, or watch the sun set from Mallory Square. Explore Fort Zachary Taylor Historic State Park, where a Civil War fort meets a beach. Its Atlantic waters offer a refreshing contrast to town.

  3. Day 4

    Grand Cayman Island

    Grand Cayman pairs clear water with an easy blend of beach and town. Ships anchor offshore; tenders land in George Town, near duty-free shops, cafés and the Cayman Islands National Museum. Boat trips reach Stingray City, where visitors can encounter southern stingrays in shallow water. Beyond town, Seven Mile Beach is known for pale sand and turquoise water. Choose a beach transfer, an island tour or time in town; Grand Cayman makes a relaxed, rewarding call.

  4. Day 6

    Santo Tomas de Castilla, Guatemala

    Santo Tomás de Castilla brings you to Guatemala’s Caribbean coast, where tropical forest meets the broad waters of Amatique Bay. The modern port lies beside Puerto Barrios, a working town with a distinctly local rhythm. Beyond the waterfront, boat journeys follow the Río Dulce toward Livingston and its Garífuna heritage. Inland, the carved Maya monuments of Quiriguá reward travelers willing to trade the coast for history.

  5. Day 7

    Harvest Caye Belize, Belize

    Harvest Caye gives cruise visitors a polished introduction to southern Belize, just offshore from Placencia. Norwegian Cruise Line developed this resort island with a long beach, a large pool and a saltwater lagoon. A swim-up bar, kayak rentals and a zip line add easy ways to fill the day. Mainland excursions reach Placencia, Maya archaeological sites and rainforest, offering a sharper sense of Belize beyond the resort.

  6. Day 9

    Cozumel, Mexico

    Cozumel, off Mexico’s Yucatán Peninsula, pairs clear Caribbean water with a lively island town. San Miguel de Cozumel offers cafés, shops and a waterfront promenade within easy reach of the cruise piers. Beyond town, reef excursions reveal why divers travel here, while San Gervasio preserves the island’s Mayan history. Choose a beach day, a guided snorkel or a drive around the coast; each shows a different side of Cozumel.

  7. Day 11

    Miami, USA

    Miami rewards travelers who look beyond its cruise terminals. South Beach pairs pastel Art Deco hotels with Ocean Drive; Little Havana serves Cuban coffee and music along Calle Ocho. The Pérez Art Museum Miami and nearby Design District reveal the city’s creative ambition. For a change of pace, Biscayne Bay and the Everglades place vivid natural landscapes within reach.

  8. Day 14

    St Thomas Island USVI

    Charlotte Amalie brings St Thomas’s history into view, from Danish colonial streets to the harbor’s busy waterfront. Explore the compact old town, where Fort Christian and pastel facades line narrow streets. Ride up to Mountain Top for broad views of Magens Bay and neighboring islands. St Thomas also offers easy access to beaches, duty-free shopping, and boat trips across the US Virgin Islands. Allow time for steep streets and port-area traffic.

  9. Day 15

    Philipsburg St Maarten, Netherlands

    Philipsburg rewards a shore day spent beyond the cruise terminal. It sits on a narrow strip between Great Bay and the Great Salt Pond. The Dutch-side capital is compact and easy to explore on foot. Front Street pairs duty-free shops with the 1793 courthouse, while the Boardwalk follows Great Bay Beach. Cross the open border into French Saint-Martin for French bakeries, lively markets and another stretch of coast.

  10. Day 16

    Basseterre St Kitts

    Begin in Basseterre, St Kitts’s compact capital, where Georgian buildings and busy market streets reveal the island’s layered past. At Independence Square, once a slave market, pause among mature trees before browsing nearby shops and cafés. Then leave town for Mount Liamuiga’s volcanic slopes, former sugar estates and beaches of dark volcanic sand. Brimstone Hill Fortress, a UNESCO World Heritage site, rewards the drive with stone ramparts and wide Caribbean views.

  11. Day 18

    Willemstad Curacao, Netherlands

    Willemstad is one of the Caribbean’s most distinctive ports, built around the deep inlet of St. Anna Bay. Punda and Otrobanda showcase Dutch colonial architecture and form part of the city’s UNESCO-listed historic area. Walk across the Queen Emma Bridge, a floating pontoon span linking the two districts. Beyond the harbor, Curaçao offers sheltered coves, clear water and beaches for an unhurried afternoon.

  12. Day 19

    Oranjestad Aruba, Netherlands

    Oranjestad makes a striking first impression: Dutch gables in Caribbean colors line streets beside a busy harbor. Beyond the waterfront, the capital’s compact center rewards a walk, with shops, cafés and landmarks including Fort Zoutman. Aruba’s dry, sunlit landscape feels close at hand, while beaches and clear water are an easy ride away. Come ashore for a relaxed city stroll, then choose whether to linger over lunch or head for the coast.

  13. Day 21

    Cartagena Colombia, Colombia

    A short ride from Cartagena’s cruise port brings you to its UNESCO-listed historic centre and handsome colonial streets. Inside the old walls, flower-draped balconies, shaded plazas and broad stone lanes lead to cafés, churches and lively markets. Visit Castillo San Felipe de Barajas, the great fortress built to defend the harbor, then explore colorful Getsemaní. Come early, before the midday heat settles over the plazas, and save time for a cool drink beside the Caribbean.

  14. Day 22

    Panama Canal, Panama

    Few journeys change your sense of scale like a passage through the Panama Canal. This 50-mile waterway links the Atlantic and Pacific, lifting ships through locks and across Gatun Lake. Watch the gates close, water rise, and a vast vessel move within inches of concrete walls. On deck, the engineering is the spectacle; beyond it, rainforest edges the route. Bring binoculars, and stay outside for the crossing.

  15. Day 22

    Panama City, Panama

    Balboa sits at the Pacific entrance to the Panama Canal, where ocean-going ships begin their passage between continents. From the port, Panama City’s skyline rises beyond the canal’s working waters. Visit Casco Viejo for restored colonial streets, independent cafés and views across the bay. Or follow the Amador Causeway toward the Biomuseo and sweeping views of ships awaiting transit. Balboa rewards travelers who look beyond the canal to a capital shaped by trade, history and the sea.

  16. Day 24

    Panama Canal, Panama

    Few journeys change your sense of scale like a passage through the Panama Canal. This 50-mile waterway links the Atlantic and Pacific, lifting ships through locks and across Gatun Lake. Watch the gates close, water rise, and a vast vessel move within inches of concrete walls. On deck, the engineering is the spectacle; beyond it, rainforest edges the route. Bring binoculars, and stay outside for the crossing.

Oceania Vista Cruises

Published August 27, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

Good to know: Prices are quoted per person based on double occupancy and include all applicable taxes and fees. Availability and prices can change quickly, so please continue through the booking process to confirm the latest availability and pricing before you pay.

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