Italy Cruise from Civitavecchia to Piraeus — 15 Days

14 nights · Italy · Departs Civitavecchia-Rome (Italy) · Visiting Salerno, Messina, Kotor, Dubrovnik, Rijeka, Trieste, Zadar, Bari, Kefalonia Island, Monemvasia, Santorini Island, Mykonos Island, Piraeus-Athens · Aboard Regent Seven Seas Cruises on the Seven Seas Prestige

Regent Seven Seas Cruises logo
Cruise lineRegent Seven Seas Cruises
ShipSeven Seas Prestige
Duration14 nights
Port calls14
Departures2 sailings
From fare$32,898 per person
Year built2026
Guests822
Cabins411
Crew630
Length257 m
Beam44 m
Cruising speed19.0 kn
  1. Day 1

    Civitavecchia-Rome, Italy

    Your ship docks at Civitavecchia, Rome’s seaport, about 50 miles northwest of the capital. Rome’s great monuments are within reach, but the port town rewards a closer look. Walk the waterfront to Forte Michelangelo, a 16th-century fortress begun under Pope Julius II; explore the old streets and market. Prefer a quieter day? The town’s seafront and nearby beaches offer an easy change of pace. Choose Rome for art and antiquity, or Civitavecchia for coastal life beyond the terminal.

  2. Day 2

    Salerno, Italy

    Salerno puts southern Italy within easy reach, with ferries and roads leading toward the Amalfi Coast. Yet the city rewards a closer look: its old lanes gather around the handsome Duomo di San Matteo. Inside, bronze doors and a richly decorated crypt recall Salerno’s medieval importance as a center of learning. Climb to Arechi Castle for broad views across the Gulf, or venture inland to the Greek temples at Paestum.

  3. Day 3

    Messina, Italy

    Messina faces Calabria across the narrow Strait of Messina, with mainland Italy visible from its waterfront. At noon, figures move across the cathedral’s clock tower, a daily spectacle best seen from the square. Nearby, Montorsoli’s 16th-century Fountain of Orion rewards a closer look. Excursions reach Taormina and Mount Etna, but Messina’s compact center also merits an unhurried walk.

  4. Day 5

    Kotor, Montenegro

    At the head of Montenegro’s Bay of Kotor, the old town sits beneath steep mountains. Enter through the Sea Gate and follow stone lanes to St Tryphon’s Cathedral. Venetian-era walls frame squares, churches, and cafés within a compact UNESCO-listed center. For a broader view, climb toward San Giovanni Fortress; the steps are demanding. Take water and allow time for the ascent, especially in summer heat. From the harbor, the bay’s changing light makes a memorable arrival and departure.

  5. Day 6

    Dubrovnik, Croatia

    Spend a day inside Dubrovnik’s UNESCO-listed Old Town, best explored on foot. Walk the city walls for close views of fortifications, roofs, and harbor. Then follow Stradun to Rector’s Palace and the Franciscan monastery. Book wall access in advance during busy months, and start early in summer. Mount Srđ offers a higher view, reached by cable car or road. Leave time for side lanes; their quieter corners reveal the city’s daily rhythm.

  6. Day 7

    Rijeka, Croatia

    Rijeka is Croatia’s working seaport, set at the head of the Kvarner Gulf beneath steep green hills. From the quays, Austro-Hungarian façades and lively Korzo make a compelling first encounter. Visit the Central Market for local produce, then head to hilltop Trsat Castle for views across the harbor and islands. Beyond the waterfront, Roman remains, grand civic buildings, and everyday cafés reveal a city shaped by many eras.

  7. Day 8

    Trieste, Italy

    Trieste rewards travellers who look beyond the waterfront. At the head of the Adriatic, this Italian city carries the marks of centuries under Habsburg rule. Start in Piazza Unità d’Italia, one of Europe’s largest seafront squares, opening directly onto the sea. Visit Miramare Castle, built for Archduke Ferdinand Maximilian, then order espresso in a city shaped by its coffee trade. Trieste is compact and cosmopolitan, with a Roman theatre and grand cafés recalling its Central European past.

  8. Day 9

    Zadar, Croatia

    Zadar pairs a compact old town with a clear Adriatic setting. Roman streets, Venetian gates and medieval churches tell the story of a city shaped by centuries of trade. On the seafront, the Sea Organ turns waves into music through stone pipes. Nearby, the Sun Salutation gathers solar energy and shines after dark. Beyond the walls, Nin’s salt pans and the island-dotted coast reward a closer look.

  9. Day 10

    Bari, Italy

    Bari is Puglia’s lively capital, with a working port and a historic center close by. Enter Bari Vecchia on foot and follow its lanes toward the Basilica of Saint Nicholas. This Romanesque church draws pilgrims and visitors to the saint’s revered relics. On Arco Basso, local women have traditionally shaped orecchiette by hand. Then cross to the seafront or browse Via Sparano’s shops and cafés. Order seafood or a plate of Puglia’s distinctive pasta before returning to port.

  10. Day 11

    Kefalonia Island, Greece

    Your first view of Kefalonia may be Argostoli, a working harbor framed by hills and the Ionian Sea. From here, roads lead to traditional villages, the underground lake at Melissani, and the sweeping shore of Myrtos Beach. Argostoli merits a pause for its palm-lined waterfront, lively market, and loggerhead turtles that forage in the harbor. Choose one excursion rather than rushing the island; winding roads make distances longer than the map suggests.

  11. Day 12

    Monemvasia, Greece

    Monemvasia rises from the sea as a sheer rock, joined to the Peloponnese by a narrow causeway. Step through its medieval gate into a stone-built town of vaulted lanes, Byzantine churches and Venetian-era mansions. Cars stay outside the lower town, leaving its steep alleys to walkers. Climb to the ruined upper fortress for wide views across the Aegean, then return for local wine and seafood.

  12. Day 13

    Santorini Island, Greece

    Few Greek islands make an entrance like Santorini, where whitewashed villages crown a volcanic caldera above the Aegean. Most cruise ships anchor offshore, and tenders land at the old port below Fira. Ride the cable car, or climb the steps, to reach the island’s capital and its celebrated views. Beyond Fira, Oia’s blue domes, the archaeological site of Akrotiri, and volcanic wines reward a longer day ashore.

  13. Day 14

    Mykonos Island, Greece

    Mykonos rewards an early start: whitewashed lanes, blue-domed churches and waterfront cafés are quieter before the cruise crowds arrive. In Little Venice, old captains’ houses lean over the Aegean, while the island’s windmills stand above the harbor. Beyond town, beaches range from lively Psarou to the broad sands of Elia. Take a short boat ride to Delos, where ancient sanctuaries and marble streets mark one of Greece’s great archaeological sites.

  14. Day 15

    Piraeus-Athens, Greece

    Piraeus is Athens’ working harbour, not a resort port—and that is its appeal. From here, the capital’s ancient landmarks are within reach, while the waterfront keeps its own busy, distinctly Greek character. Visit the Archaeological Museum of Piraeus, then linger over grilled fish in Mikrolimano, a small harbour lined with tavernas. Metro connections make central Athens straightforward. Or stay near the water and watch ferries depart for the islands.

Seven Seas Prestige Cruises

Published August 27, 2026
Last updated October 3, 2026
Author: J. Richard


Cruise Disclosure

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